Leukemia Physician's Perspective on Transplant in Patients with TP53 Mutated Acute Myeloid Leukemia
Moreno Vanegas Y, El Khatib S, Hisrich B, Coltoff A, Shallis R, Patel A, Bewersdorf J, Oh T, Abaza Y, Foucar C, Goldberg A, Duvall A, Atallah E, Litzow M, Badar T. Leukemia Physician's Perspective on Transplant in Patients with TP53 Mutated Acute Myeloid Leukemia. Blood 2024, 144: 1487-1487. DOI: 10.1182/blood-2024-205782.Peer-Reviewed Original ResearchAcute myeloid leukemiaTP53-mAllo-HCTComplex cytogeneticsHypomethylating agentsInternational consensus classificationRefractory diseaseSecondary AMLOverall survivalMyeloid leukemiaTP53-mutated acute myeloid leukemiaDe novo acute myeloid leukemiaProgressive acute myeloid leukemiaSecondary acute myeloid leukemiaAllogeneic hematopoietic cell transplantationMedian overall survivalTP53 allelic stateIncomplete count recoveryLow-intensity regimensReviewed electronic medical recordsHematopoietic cell transplantationRate of relapseMulticenter observational studyOverall response ratePatient selection criteriaGENETIC VARIANTS OF UNCERTAIN SIGNIFICANCE IN PATIENTS WITH PRESENTATIONS CONCERNING FOR INBORN ERRORS OF IMMUNITY
Novotny S, Yoo N, Granoth M, Chen J, Osmani L, Kang I, Shin J. GENETIC VARIANTS OF UNCERTAIN SIGNIFICANCE IN PATIENTS WITH PRESENTATIONS CONCERNING FOR INBORN ERRORS OF IMMUNITY. Annals Of Allergy Asthma & Immunology 2024, 133: s60. DOI: 10.1016/j.anai.2024.08.200.Peer-Reviewed Original ResearchInborn errors of immunityClinical presentationOrganelle biogenesisGenetic resultsT cellsAssociated with distinct clinical presentationInborn errors of immunity patientsGenetic testingClinical presentation of patientsDiagnosis of inborn errors of immunityImmune functionImmune thrombocytopenic purpuraReviewed electronic medical recordsT cell immunityErrors of immunityPresentation of patientsB cell immunityGene groupsCytomegalovirus infectionVariable immunodeficiencyThrombocytopenic purpuraRate of rheumatoid arthritisPediatric patientsGenetic variantsB cells
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