2008
An Arabidopsis F-box protein acts as a transcriptional co-factor to regulate floral development
Chae E, Tan Q, Hill TA, Irish VF. An Arabidopsis F-box protein acts as a transcriptional co-factor to regulate floral development. Development 2008, 135: 1235-1245. PMID: 18287201, DOI: 10.1242/dev.015842.Peer-Reviewed Original ResearchConceptsUNUSUAL FLORAL ORGANSAP3 promoterLFY activityTranscription factorsProtein degradationFloral homeotic gene expressionLEAFY transcription factorFloral homeotic genesHomeotic gene expressionTranscriptional repressor domainF-box proteinsSCF ubiquitin ligaseF-box componentAPETALA3 (AP3) geneHomeotic genesRepressor domainFloral organsFlower developmentPlant speciesTranscriptional complexPlants flowerProtein actsFloral developmentUbiquitin ligaseEndogenous signals
2001
The Sp1-like Protein BTEB3 Inhibits Transcription via the Basic Transcription Element Box by Interacting with mSin3A and HDAC-1 Co-repressors and Competing with Sp1*
Kaczynski J, Zhang J, Ellenrieder V, Conley A, Duenes T, Kester H, van der Burg B, Urrutia R. The Sp1-like Protein BTEB3 Inhibits Transcription via the Basic Transcription Element Box by Interacting with mSin3A and HDAC-1 Co-repressors and Competing with Sp1*. Journal Of Biological Chemistry 2001, 276: 36749-36756. PMID: 11477107, DOI: 10.1074/jbc.m105831200.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid MotifsAnimalsBinding, CompetitiveBlotting, WesternCell Cycle ProteinsCHO CellsCricetinaeGenes, ReporterGlutathione TransferaseHistone Deacetylase 1Histone DeacetylasesKineticsKruppel-Like Transcription FactorsMolecular Sequence DataPlasmidsPrecipitin TestsPromoter Regions, GeneticProtein BindingProtein Structure, TertiaryRepressor ProteinsSin3 Histone Deacetylase and Corepressor ComplexSp1 Transcription FactorTrans-ActivatorsTranscription, GeneticZinc FingersConceptsCo-repressorN-terminusHDAC-1Bind GC-rich sequencesC-terminal zinc finger motifsGC-rich DNA elementsCo-repressor mSin3ASp1-like proteinsZinc finger motifsDNA-binding domainGC-rich sequencesSp1-like activityGel shift assaysMammalian cell homeostasisMechanism of repressionChinese hamster ovary cellsFinger motifDNA elementsSp1 familyRepressor domainRepressor proteinBTEB3GAL4 assayTranscriptional repressionTranscriptional repressor
1999
Regulation of parathyroid hormone-related protein gene expression in murine keratinocytes by E1A isoforms: a role for basal promoter and Ets-1 site
Foley J, Wysolmerski J, Missero C, King C, Philbrick W. Regulation of parathyroid hormone-related protein gene expression in murine keratinocytes by E1A isoforms: a role for basal promoter and Ets-1 site. Molecular And Cellular Endocrinology 1999, 156: 13-23. PMID: 10612419, DOI: 10.1016/s0303-7207(99)00151-3.Peer-Reviewed Original ResearchMeSH KeywordsAdenovirus E1A ProteinsAnimalsBase SequenceBinding SitesCell Line, TransformedEnhancer Elements, GeneticGene Expression RegulationGenes, rasGenes, ReporterKeratinocytesLuciferasesMiceParathyroid HormoneParathyroid Hormone-Related ProteinPromoter Regions, GeneticProtein IsoformsProteinsProto-Oncogene Protein c-ets-1Proto-Oncogene ProteinsProto-Oncogene Proteins c-etsRNA, MessengerTranscription FactorsTranscription, GeneticConceptsGene expressionBasal promoterReporter constructsEts-1 siteMinimal promoter regionProtein gene expressionTransient transfection assaysReporter gene activityRepressor domainE1A oncoproteinGene activityRas transformationE1A isoformsMurine keratinocyte lineSite upstreamReporter geneTransfection assaysPromoter regionParathyroid hormone-related protein gene expression
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