ESCRT-III activation by parallel action of ESCRT-I/II and ESCRT-0/Bro1 during MVB biogenesis
Tang S, Buchkovich N, Henne W, Banjade S, Kim Y, Emr S. ESCRT-III activation by parallel action of ESCRT-I/II and ESCRT-0/Bro1 during MVB biogenesis. ELife 2016, 5: e15507. PMID: 27074665, PMCID: PMC4865371, DOI: 10.7554/elife.15507.Peer-Reviewed Original ResearchMeSH KeywordsCell MembraneEndosomal Sorting Complexes Required for TransportGene Expression Regulation, FungalMultivesicular BodiesMutationProtein DomainsProtein Structure, SecondaryProtein TransportSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSignal TransductionUbiquitinated ProteinsUbiquitinationConceptsESCRT-III activityESCRT-IIIESCRT-III-mediated membrane remodelingESCRT-III subunit Snf7N-terminal core domainESCRT-III subunitsMembrane remodeling eventsEndosomal Sorting ComplexUbiquitin-dependent pathwayUpstream ESCRTsFunctional divergenceMVB biogenesisESCRT componentsSorting complexMembrane remodelingC-terminusSnf7Molecular explanationRemodeling eventsCore domainOrthologsPolymerization stateYeastX-ray crystal structurePathway
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