2023
Tunable Mesoscopic Collagen Island Architectures Modulate Stem Cell Behavior
Nguyen R, Cabral A, Rossello‐Martinez A, Zulli A, Gong X, Zhang Q, Yan J, Mak M. Tunable Mesoscopic Collagen Island Architectures Modulate Stem Cell Behavior. Advanced Materials 2023, 35: e2207882. PMID: 36895051, PMCID: PMC10166061, DOI: 10.1002/adma.202207882.Peer-Reviewed Original ResearchConceptsStem cell behaviorCell behaviorPluripotent stem cellsMesenchymal stem cell behaviorMammalian cellsMesodermal differentiationCell migrationExtracellular matrixStem cellsOsteogenic differentiationRegional enrichmentCollagen-based hydrogelsPhysiological tissuesBioactive cuesDifferentiationBiophysical environmentCollagen hydrogelsCellsIslandsComplex architectureTissue engineering applicationsTissueCollagen architectureEnrichmentGel
2021
Enrichment of Disease-Associated Genes in Cortical Areas Defined by Transcriptome-Based Parcellation
Gryglewski G, Murgaš M, Klöbl M, Reed MB, Unterholzner J, Michenthaler P, Lanzenberger R. Enrichment of Disease-Associated Genes in Cortical Areas Defined by Transcriptome-Based Parcellation. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2021, 7: 10-23. PMID: 33711548, DOI: 10.1016/j.bpsc.2021.02.012.Peer-Reviewed Original ResearchConceptsGenome-wide association studiesGene setsEnrichment analysisAssociation studiesDistinct gene expression profilesCortical areasDisease-associated genesGene expression profilesEnrichment patternsSimilar enrichment patternsExpert-curated databasesNovel disease mechanismsTranscriptome dataBrain disordersPleiotropic genesSpecific genesExpression profilesGenesMicroarray dataSpecific cortical areasAmyotrophic lateral sclerosisInferior parietal lobuleFunctional differentiationTranscriptomeRegional enrichment
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