Gerald I Shulman MD, PhD

George R. Cowgill Professor of Medicine (Endocrinology) and Professor of Cellular and Molecular Physiology; Investigator, Howard Hughes Medical Institute

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Medicine, Pharmacology, and Physiology

Mouse Metabolic Phenotyping Center

Cellular & Molecular Physiology: Epithelial Transport of Ions and Solutes | Organ Physiology | Physiology of Human Disease | Physiology and Integrative Medical Biology Track | Graduate Program in Cellular and Molecular Physiology

Internal Medicine: Endocrinology: Diabetes Center | Diabetes Research Center

Center for X-Linked Hypophosphatemia, Yale

Research Interests

Molecular mechanisms responsible for insulin resistance  more...


  • BS, University of Michigan, Ann Arbor, MI, 1974
  • M.D., Wayne State University, 1979
  • Ph.D., Wayne State University, 1979

Selected Publications

  • Shulman GI, Rothman DL, Jue T, Stein P, DeFronzo RA, Shulman RG. Direct quantitation of muscle glycogen synthesis in normal man and noninsulin-dependent diabetics by 13C Nuclear Magnetic Resonance Spectroscopy. N Eng J Med, 322:223-8, 1990.
  • Rothman DL, Magnusson I, Katz LD, Shulman RG, Shulman GI. Quantitation of Hepatic Glycogenolysis and Gluconeogenesis in Humans with 13C NMR. Science, 254:573-6, 1991.
  • Dresner A, Laurent D, Marcucci M, Griffin ME, Dufour S, Cline GW, Slezak LA, Andersen DK, Hundal RS, Rothman DL, Petersen KF, Shulman GI. Effect of free fatty acids on IRS-1 associated phosphatidyl inositol 3-kinase activity. J Clin Invest, 103:253-9, 1999.



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