Our Lab Team

Bio Profile

Pasko Rakic, MD, PhD

Dorys McConnell Duberg Professor of Neuroscience and Professor of Neurology

Research Interests

Central Nervous System; Neurobiology; Neurology; Apoptosis; Cell Proliferation

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Current Lab Members


Bio Profile

Albert E Ayoub, PhD

Research Interests

Congenital Abnormalities; Cerebral Cortex; Neurobiology; Prenatal Diagnosis; Mental Disorders Diagnosed in Childhood

My research is focused on transcriptional and regulatory programs that precisely orchestrate the formation of the neocortex. Disruption of these mechanisms cause neurological and psychological disorders. I apply a systems biology approach in combination with molecular genetics to decipher both conserved and species-specific developmental mechanisms.

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Bio Profile

Yury Morozov, PhD

Research Interests

Central Nervous System; Neurodegenerative Diseases

Many years of experience in worldwide laboratories (Russia, France, Norway and Hungary) lend to expertise in the methods of scanning and transmission electron microscopy including pre- and post-embedding immunolabeling. This also let me introduce to Yale the method of three-dimensional reconstruction of large cell fragments such as neuron cell bodies or processes from serial electron micrographs.

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Bio Profile

Brian Grayson Rash, PhD

Research Interests

Anatomy; Brain; Cell Biology; Embryology; Disorders of Environmental Origin; Nervous System Malformations; Neurosciences; Stem Cells; Embryo Research; Fetal Research; Genetic Research; Neurogenesis; Optogenetics; Chemicals and Drugs

My research focuses on the molecular and cellular basis of early cerebral cortex development. I study how cortical stem cells, known as radial glial cells, proliferate and differentiate into post-mitotic neurons. With modern optogenetic methods, we are uncovering key cellular dynamics of cortical stem cells during neurogenesis which are important for brain growth and gyrification—the process of cortex folding during development (see Rash BG et al., 2016, Sci. Adv., and Rash BG et al., 2013, J....

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Students


Bio Profile

Jamie Benoit

Graduate Student

Summary of Research and Future Directions: My interest is in how neurons change their connectivity and structure during the "critical period" of development and how this may be applicable to human disorders. Currently, I am investigating the possibility of inducing critical period-like synaptic plasticity in an adult

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Bio Profile

Martin H. Dominguez

Md/PhD Student

I am interested in developmental dynamics, i.e. changes to the neural stem cell niche as development proceeds through time. I am interested in neural molecular identity, differentiation, and cell fate restriction in early cortical progenitors. My thesis work focuses on the interactions between both novel and well-established transcriptional regulators in cortex development.

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Staff


Bio Profile

Katherine A Bownes

Sr. Administrative Assistant

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Bio Profile

Michelle M. Pizzuti

Cerebral Cortex Editorial Assistant

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Former Lab Members

Graduate Students (GS) and Postdoctoral Fellows (PF) in chronological order

Richard Nowakowski, GS, Prof. & Chair, Neurobiology, UFL, Tallahassee
Carla Shatz, PF, Professor & Director, Bio-X, Stanford University, Palo Alto, CA
Ivica Kostovic, PF, Director, Croatian Brain Institute, University of Zagreb, Croatia
Pat Levitt, PF, Professor, Zilkha Neurogenetic Institute, USC, LA, CA
Anthony La Mantia, GS, Prof. & Chair, Neuroscience Inst., GWU, Washington, DC
Nada Zecevic, GS, Professor, UConn Health Center, Farmington, CT
Jean-Pierre Bourgeois, PF, Researcher CNRS, Pasteur Institute, Paris, France
Rodrigo Kuljis, PF, Prof. & Chair, Neurology, University of Miami,  FL 
Robert Williams, PF, Prof. & Chair, Computational Genomics, UTHSC, Memphis, TN
Douglas Meinecke, PF, Chief, Developmental Neuroscience Program, NIMH, Bethesda, MD
Richard Cameron, PF, Assoc. Professor, Medical College of Georgia, Augusta, GA
Hitoshi Komuro, PF, Assoc. Professor, Cleveland Clinic Foundation, OH
Eva Anton, PF, Professor, University of North Carolina, Chapel Hill, NC
David Kornack, PF, Assoc. Professor, University of Rochester, NY
Maria Donoghue, PF, Assoc. Professor, GWU,  Washington, DC
Chia-Yi (Alex) Kuan, GS, PF, Associate Professor, UC, Cincinnati, OH
Tarik Haydar, PF, Professor, Boston University, MA
Nenad Sestan, GS, PF, Professor, Yale University, New Haven, CT
Skirmantas Janusonis, PF, Assoc. Professor, UC Santa Barbara, CA
Matthew Sarkisian, PF, Assist. Professor, UFL, Gainesville, FL
Xiu-Xin Liu, PF, Asst. Professor. University of Rochester, NY
Joshua Breunig, GS, PF, Assist. Professor, Cedars-Sinai MC, LA, CA
Kazue Hashimoto-Torii, PF, Assist. Professor, CNMC at GWU, Washington, DC
Masaaki Torii, PF, Assist. Professor, CNMC at GWU, Washington, DC