Bio Profile

Elias Lolis, PhD, BA

Professor of Pharmacology

Director of Graduate Studies

Research Interests

Education; Immune System Diseases; Inflammation; Neoplasms; Parasitic Diseases; Pharmacology; Crystallography, X-Ray; Enzymes and Coenzymes; High-Throughput Screening Assays

Elias Lolis received his PhD in 1989 from MIT in Chemistry/Biochemistry studying the three-dimensional structure and mechanism of triosephosphate isomerase. He was a postdoctoral associate at the Laboratory of Medical Biochemistry at Rockefeller University studying the functional interaction between advanced glycation end products (AGEs) and the immune system. He joined the Yale faculty in 1991 as an Assistant Professor focusing on the structure, mechanism, and inhibition of chemokines,...

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Gregg V Crichlow, PhD

Visiting Research Scientist in Pharmacology

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Leepakshi Khurana

Postdoctoral Associate

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James W Murphy, PhD

Associate Research Scientist in Pharmacology

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Georgios Pantouris

Associate Research Scientist

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Deepa Rajasekaran, PhD

Visiting Research Scientist

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Matthew R Dean


Zachary Gannam

Graduate Student

Cali Inferrera


Georgia Loucopoulos

Postgraduate Student

Eric Rosenberg

Graduate Student

Pre & Post Graduate Alumni

Trainee Period Type Prior Degree Research Project Current Position
Natalie Drucker 2013-2014   BS, Yale University CXCR4 small molecule ligands Yale Club, NYC
Mansur Ghani 2012-2014   BS, Yale University pKa of D-dopachrome tautomerase Yale MD Student
Yoonsang Cho 2005-2012 Post PhD, 2005, Texas A&M Univ. Parasitic and human MIF inhibition Assistant Prof, Dept of Biochem, St. Louis Univ.
Gregg Crichlow 2002-2011 Post PhD, 2002, Univ. of CT Human MIF inhibition Dir Structural Biology, Innovimmune Biotherapeutics
Swen Zierow 2006-2009 Pre\Post PhD, 2008, Univ. of Aachen, Germany Parasitic MIF, human D-dopachrome tautomerase Lab Head, DSP-Development, Sandoz, Austria
Kai Kevin Jin 2002-2004 Post PhD, 2002, Univ. of Southern California MIF-MIF receptor Basic Life Sci Res Assoc, Stanford University
Thomas Scheuermann 1999-2004 Pre BS, 1996, Gordon College, Wenham, MA Thiopurine methyltransferase structure Field Applications Specialist, GE Life Sciences
Jodi Lubetsky (Yellin) 1997-2002 Pre BS, 1996, MIT MIF structure-function Director, Science Policy, American Association of Medical Colleges
Aristidis Sachpatzidis 1997-2002 Pre BS, 1996, Aristotle University of Thessaloniki, Greece Chemokine structure-function Assoc Res Sci, Orthopaedics, Yale University
Michael Sachsmanoglou  2000-2002 Post MD, 1994, Aristotle University of Thessaloniki, Greece eNOS-caveolin-complex; Cytoplasmic cytokine domains M.D. – Greece
Sanjeev Jain 2000-2001 Post MD/PhD, 1990, Univ. of Wisconsin, Madison eNOS-caveolin complex; GATA-3 Columbia Asthma & Allergy Clinic
Marc Deller 2000-2001 Post PhD, 2000, University of Oxford, UK Cytoplasmic cytokine domains Research Associate, Scripps Institute
Michael Hodsdon 2000-2001 Post MD/PhD 1997, Washington University, St. Louis, MO vMIP-II interactions with chemokine receptors Associate Professor, Yale University
Chris Dealwis 1996-1999 Post PhD, 1993. Birkbeck College, England Stromal cell-derived factor-1a (SDF-1a) structure-function Associate Professor, Case Western Reserve University
Elias Fernandez 1996-2001 Post PhD, 1995, Loyola University of Chicago SDF-1a and viral macrophage inflammatory protein II (vMIP-II) Associate Professor, University of Tennessee
Theodora Pinou 1994-1996 Post PhD, 1993, New York University Chemokine receptors Associate Professor, Western Connecticut State University
Melissa Swope (Willis) 1993-1998 Pre BS, 1992, Central Missouri State University MIF structure-function Project Officer, Division of CBRN Countermeasures, US Department of Health and Human Services U.S.
L. Fred Jerva 1993-1996 Pre BS, 1990, College of Notre Dame Macrophage inflammatory protein-2 structure-function Clinical Information Science Directory, AstraZeneca
Hong-Wei Sun 1992-1996 Post PhD, 1992, University of Iowa MIF structure-function Chief, Biodata Mining & Discovery NIAMS, NIH

High School and Undergraduate Alumni

Student Period Status Degree Research Project Current Position
Danielle Katz 1992-1993 Yale Undergrad Thesis Student BS, Yale College, 1993 MD, SUNY, Albany Med. School, 1997 MIP-2 mutants Associate Professor, Department of Orthopedic Surgery, Upstate Medical University
Sophia Tsaklakrides 1993-1994 Yale Undergrad BS, Yale College, 1994  MIP-1alpha Senior Study Director, Health Studies at Westat, Rockville, MD
Yonhee Cha 1994-1995 Undergrad BS, Wesleyan Univ., 1995 MD, SUNY Downstate Medical School, 1999  MIP-1alpha MD, Long Island Jewish Med Ctr
Robert M Turner, Jr. Summer, 1994 Biostep BS, Morehouse College, 1995 Interactions of the Erythropoietin Receptor Accenture Consulting
PhD, Yale Univ., 2002
Rani Lopez 1995-1996 Postgrad
Akilah F Weber Summer, 1997 Biostep BS, Xavier Univ., 2000 MD, Univ of Rochester Medical School, 2004 Expression and Purification of Macrophage Inflammatory Protein-2 Assistant Professor, UT Southwestern Medical Center
Migdelisel Colon Summer, 1998 Biostep University of Puerto Rico, Mayaguez Campus deoxycytidine kinase
Andre Matthews 1999-2005 Biostep MD Thesis BS, Morehouse College 2000 MD, Yale School of Medicine, 2005 Emory Univ, Emergency Medicine Residency, 2005-2008 vMIP-II Mutagenesis: Locating the Binding Site of a Novel Viral Protein Associated with HHV-8 Associate Professor, Emory School of Medicine, Emergency Medicine
Robert Peace 2001-2 Yale Undergrad BS, Yale College, 2002 Enzymatic studies of MIF Deceased
Alvaro Huerta 2003 Yale Undergrad BS, Yale College, 2003 NEMO cloning and mutagenesis Stanford Law School
Jason W Gilleylen Summer, 2004 Summer, 2005 Biostep BS, Morehouse College, 2006, MD, Columbia School of Physicians and Surgeons, 2012 Co-crystallization of Mus Musculus Mitogen Activated Protein Kinase Phosphatase-1 With P38 and ERK-1  Resident, Beth Israel Deaconess Medical Center
Kemunto Makaya 2004-2005 Yale Undergrad Thesis student BS, Yale College MD, Yale School of Medicine, 2009 Insights from the SDF-1/CXCR4 system in yeast Resident, UCSF
Catherine Chen 2005 Biostep BS, Johns Hopkins Univ, 2005 MS, Yale School of Medicine, 2010 An Inside Look at Cancer Metastasis: Protein Interactions with CXCR4 via SDF-1 Mediated Signaling Pharmacology Grad Student, Yale Univ
Michelle Kim 2006-2007 High School Kinetic analysis of parasitic MIF Undergrad, Boston University
Ajala Osagie 2008 Biostep BS, Rutgers Univ., 2009 Mapping of CXCR4 N-terminus residues critical for ligand binding and activation. Grad Student, University of Medicine and Dentistry of New Jersey
Trent Worrell 2008-2009 Postgrad BS, 2008, Tufts Univ. AMPA receptor regulatory protein
Jeeha Park 2008-2011 Undergrad Kinetic and migration assay of MIF Undergrad, University of Connecticut
Demetra Sklaviadis Summer, 2009 High School Anatolia College (HS), 2010 Hookworm MIF co-crystallization MIT undergrad
Rubi Luna 2010 Biostep BS, Johns Hopkins Univ., 2012 Real-time MIF-CXCR2 signaling Undergrad, Johns Hopkins Univ
Kevin Kim 2010-2011 High School Gene Cloning Undergrad, Brown University
Srujana Saibiwar 2011-present Grad MS, 2005, Kakatiya University, India Cellular studies of MIF receptors MS, University of New Haven

ee Eun Park

2011 High School Purification of MIF Cheshire High School
Gee Young Jung 2011 Undergrad Cell line studies with MIF Undergrad, University of Connecticut
Malin Havstadius Summer 2013, 2014 High School CXCR4 mutants/tyrosylprotein sulfotransferase  
Gabrielle Hummel Summer 2014 High School Ras-like domain  
Richard Nelli Summer 2014 High School Enterokinase purification