UltraMild Synthesis

  • Some modifications require the use of UltraMild columns, phosphoramidites and reagents that allow for mild cleavage and deprotection conditions. Some of these modifications include:
cyanine dyes including Cy3, Cy3.5, Cy5 and Cy5.5
TAMRA-dT and 3'-TAMRA
 acridine
 etheno-dA
 5,6-Dihydro-dU
 5'-iodo-dT
 5'-OH-dU
 5'-OH-dC
thymidine glycol

  • The price of these UltraMild columns, phosphoramidites and reagents along with the price of any modified phosphoramidites will be added to the normal oligo price.

Please see our Modifier Pricing Page for UltraMild reagent prices.