Henry Klar Yaggi, MD, MPH

Associate Professor of Medicine (Pulmonary); Director, Yale Centers for Sleep Medicine

Research Interests

Apnea; Arrhythmias, Cardiac; Health Services Administration; Investigative Techniques; Cardiomyopathies; Therapeutics; Health Care

Public Health Interests

Respiratory Disease/Infections; Stroke

Research Organizations

Internal Medicine: Pulmonary, Critical Care & Sleep Medicine

Faculty Research

Office of Cooperative Research

Research Summary

Dr. Yaggi is an Associate Professor of Medicine at the Yale University School of Medicine and Director of the Yale Program in Sleep Medicine. He is board certified in Internal Medicine, Pulmonary Medicine, Critical Care, and Sleep Medicine. He is a Principal Investigator at the national VA Clinical Epidemiology Research Center. His research interest is the clinical epidemiology of sleep-disordered breathing, with a focus on the diverse health implications of sleep apnea and an emphasis on informing clinical care. Within this larger domain, his work has focused on 3 specific topics: sleep apnea as a risk factor for adverse cardiovascular and metabolic health outcomes; prognostic factors for adverse cardiovascular and metabolic health outcomes in patients with sleep-disordered breathing; and the impact of diagnosing and treating sleep apnea (using home-based strategies) on cardiovascular risk.

Extensive Research Description

Principal Investigator at the national VA Clinical Epidemiology Research Center. His research interest is the clinical epidemiology of sleep-disordered breathing, with a focus on the diverse health implications of sleep apnea and an emphasis on informing clinical care. Within this larger domain, his work has focused on 3 specific topics: sleep apnea as a risk factor for adverse cardiovascular and metabolic health outcomes; prognostic factors for adverse cardiovascular and metabolic health outcomes in patients with sleep-disordered breathing; and the impact of diagnosing and treating sleep apnea (using home-based strategies) on cardiovascular risk.

Agency: VA Clinical Science Research and Develop I.D.# Merit Review Award Title: “Oxygen versus PAP for treatment of sleep apnea in chronic heart failure” P.I.: Yaggi/Gottlieb Role: Principal Investigator Percent effort: 35% Direct costs per year: $250,000 Total costs for project period: $1,500,000 Project period: 10/01/2012 – 09/30/2016

Agency: National institute of Health/National Institute of Nursing Research I.D.# 1P20NR014126-01 Title Yale Center for Sleep Disturbance in Acute and Chronic Conditions P.I. Henry Klar Yaggi, M.D. M.P.H. Percent Effort: 12.5% Direct costs per year: $250,000 Total costs for project period: $1,250,000 Project period: 10/01/2012-9/30/2017

Agency: NIH National Heart Lung and Blood institute (NHLBI) I.D.# U34 HL105285-01 Title: “Sleep Apnea in TIA/ Stroke: Reducing Vascular Risk with CPAP (SLEEP TIGHT)” P.I.: Henry Klar Yaggi, M.D. M.P.H. Percent effort: 30% Direct costs per year: $500,000 Total costs for project period: $2,000,000 Project period: 10/01/2010 – 06/31/2014

Agency: NIH National Heart Lung and Blood institute (NHLBI) I.D.# R21 MD006769 Title: “Multi-Level Modeling of Social Disparities in Sleep and Health” P.I.: Andre Araujo, Ph.D Role: Co-investigator Percent effort: 5% Direct costs per year: $250,000 Total costs for project period: $500,000 Project period: 10/01/2011 – 09/30/2014

Selected Publications

Full List of PubMed Publications

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Contact Info

Henry Klar Yaggi, MD, MPH
Patient Care Locations
Yale Pulmonary & Critical Care MedicineVA Connecticut Healthcare
950 Campbell Avenue

West Haven, CT 06516
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Yale Sleep DisordersFitkin Memorial Pavilion
789 Howard Avenue, Ste Winchester Chest Clinic

New Haven, CT 06519
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Yale Sleep Medicine Centers1291 Boston Post Road, Ste Suite 202
Madison, CT 06443
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Yale Pulmonary & Critical Care MedicineYale New Haven Hospital
20 York Street

New Haven, CT 06510
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Yale Sleep Medicine Centers8 Devine Street
North Haven, CT 06473
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Mailing Address
PO Box 208057
300 Cedar Street

New Haven, CT 06520-8057

Yale Program in Sleep