HIV/AIDS (including HIV in patients with malignancies)

The Yale HIV/AIDS program, formally established in 1991 is comprised of faculty, multi-disciplinary staff and trainees who focus on: HIV-related clinical care delivery including HIV treatment and prevention; basic, translational, implementation science and clinical research occurring domestically and at international sites; clinical trials on relevant novel therapeutics and vaccines; educational programs for diverse learners in inpatient, outpatient and community-based settings.

The mission of the Yale HIV/AIDS Program is to offer high quality competent, comprehensive, compassionate, coordinated and culturally appropriate care to people with or at risk for HIV and advance understanding of disease pathogenesis, complications, treatment and prevention and to study and/or address important issues affecting persons with HIV (PWH) such as aging, comorbid conditions such as substance use and mental health disorders.

1. Provide expert consultation and state-of-the art clinical services to people at risk for or living with HIV in hospital, clinic and community settings
2. Foster collaborative research across various departments and schools within and outside Yale University to create innovative and implementable models of care to improve care for persons and communities affected by HIV and associated conditions.
3. Support and develop educational and training programs to develop, mentor and nurture the next generation of HIV providers, researchers, and patient advocates.

HIV Outpatient Clinics (formerly Nathan Smith Clinic and Haelen ID Center) are housed within the Yale-New Haven Health system and provide outpatient care services to over 1500 gender, racially and ethnically diverse PWH. The multidisciplinary care team includes physicians of various specialties (psychiatry, neurology, general medicine, addiction medicine, transplant), registered nurses, social workers, counselors, peer navigators and other support staff.

The Donaldson Firm of the Yale-New Haven Hospital, located on the 9/5 wing of the East Pavilion, is a dedicated inpatient ward staffed by Yale housestaff and other trainees and supervised by infectious diseases faculty including HIV Program faculty. Together with nursing and other support staff, the Firm specializes in providing clinical services for inpatient PWH with HIV-related (including acute HIV and opportunistic infections) and non-HIV related complications.

The Community Healthcare Van, supported by various community-based funds, provides mobile services throughout New Haven including syringe services, pre-exposure prophylaxis (PrEP) and directly observed HIV and Methadone treatment.

The Yale HIV/AIDS Program boasts many well renowned faculty of varied interests and specialties who have extensive grant-funded projects highlighted in the following areas:

International:

• Implementation science to scale up HIV prevention and treatment in Eastern Europe/Central Asia
• Innovations to promote HIV testing and PrEP in MSM and transgender women
• Trials of long-acting injectables for HIV prevention and opiate use disorder
• Integration of HIV and TB care

Domestic:

• Integrating substance use treatment research with Infectious Diseases
• Providing access to medication assisted treatment for opiate use disorder to persons in prison and jail
• Providing services focused on HIV and women’s health
• Providing community collaborative models to improve care for persons with HIV and HCV, aging PWH

Clinical Trials:

• Antivirals and vaccines research program that studies novel therapeutics and strategies for HIV treatment and prevention; vaccines for multiple infectious diseases including bacterial and viral infections (e.g. SARS-CoV-2).

The Yale HIV/AIDS Program provides a rich breadth of educational programs and activities for medical students, residents, fellows and other trainees. These include the specialized Yale HIV training track established in 2012 to train primary care residents in HIV care. Educational activities include the weekly core didactic HIV ambulatory curriculum, and monthly HIV research club. The CT site of the New England AIDS Education Training Center (AETC) is run by faculty at the Yale AIDS Program and provides timely educational programs relevant to HIV care for practitioners across CT.