The Research Pathology and Histology Core offers an array of routine and specialized services that support research using rodent and other animal models.
The Histology Core specializes in producing high quality sections using approaches customized to specialized projects, such as embryo studies, neuroanatomical studies or construction of tissue microarrays. In addition, the Histology Core offers a wide array of routine services such as tissue embedding, frozen sectioning and routine or special stains.
The Phenotyping Core offers fee-for-service and collaborative support. This includes custom tissue collection, as well as whole mouse phenotyping, and study design or slide review by an anatomic pathologist.
Recent publications supported by the Research Pathology and Histology Core
Senejani AG, Liu Y, Kidane D, Maher SE, Zeiss CJ, Park HJ, Kashgarian M, McNiff JM, Zelterman D, Bothwell AL, Sweasy JB. Mutation of POLB causes lupus in mice. Cell Rep. 2014 Jan16;6(1):1-8
Belperron AA, Liu N, Booth CJ, Bockenstedt LK. Dual role for Fcy receptors in host defense and disease in Borrelia burgdorferi-infected mice. Front Cell Infect Microbiol. 2014 Jun 11;4:75.
Caporizzo DJ, Kwiatkowski AE, Chen MK, Beck AP, Booth CJ, Zeiss C, Smith PC, Carlson Scholz JA, Wilson SR. Use of (18)F-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography to Aid in Diagnosing Intestinal Adenocarcinoma in 2 Rhesus Macaques (Macaca mulatta). Comp Med. 2014;64(3):211-20.
Cao J, Liu A, Cheung WK, Zhao M, Chen SY, Chan SW, Booth CJ, Nguyen DX, Yan Q. Histone demethylase R8P2 is critical for brease cancer progression and metastasis. Cell Rep. 2014 Mar13;6(5):868-77.
Beck AP, Erdelyi I, Zeiss CJ. Endometrial decidualization and deciduosis in aged rhesus macaques (Macaca mulatta). Comp Med. 2014 Apr;64(2):148-56.
Go GW, Srivastava R, Hernandez-Ono A, Gang G, Smith SB, Booth CJ, Ginsberg HN, Mani A. The combined hyperlipidemia caused by impaired Wnt-LRP6 signaling is reversed by Wnt3a rescue. Cell Metab. 2014 Feb 4;19(2):209-20.
Juneja SC, Vonica A, Zeiss C, Lezon-Geyada K, Yatsula B, Sell DR, Monnier VM, Lin S, Ardito T, Eyre D, Reynolds D, Yao Z, Awad HA, Yu H, Wilson M, Honnons S, Boyce BF, Xing L, Zhang Y, Perkins AS. Deletion of Mecom in mouse results in early-onset spinal deformity and osteopenia. Bone. 2014 Mar;60:148-61.