Sandy Chang PhD, MD

Associate Professor of Laboratory Medicine and of Pathology; Associate Director, Molecular Diagnostics Laboratory

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Medicine, Pharmacology, and Physiology

Office of Student ResearchRadiobiology & RadiotherapyPathology | Laboratory Medicine: Molecular Diagnostics

Research Interests

Mouse models of cancer; DNA damage; Telomere biology more...


  • BS, Yale University, 1988
  • Ph.D., Rockefeller University, 1996
  • M.D., Cornell University Medical College, 1997

Selected Publications

  • Chang S. 2013. Cancer chromosomes going to POT1. Nat Genet. 45(5):473-475.
  • Gu P, Deng W, Lei M, and Chang S. 2013. Single strand binding proteins 1 and 2 protect newly replicated telomeres. Cell Research 23(5):705-719. See accompanying review "Mouse models uncap novel roles of SSBs" Bain AL, Shi W, Khanna KK. 2013 Cell Res. 2013 Jun;23(6):744-5.
  • Chang S. 2012. Chromosome ends teach unexpected lessons on DNA damage signalling. EMBO J. 31:3380-3381.



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