Leonard Konrad Kaczmarek PhD

Professor of Pharmacology and of Cellular and Molecular Physiology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Neuroscience | Molecular Medicine, Pharmacology, and Physiology

Office of Student ResearchInterdepartmental Neuroscience ProgramCellular & Molecular Physiology: Membrane Proteins - Ion Channels; Membrane Biophysics; Cellular Neurophysiology; Graduate Program in Cellular and Molecular Physiology | Pharmacology: Neuropharmacology

Research Interests

Neuroscience; Learning and memory; Ion channels more...


  • Ph.D., University of London, 1971

Selected Publications

  • Barcia, G., Fleming, M.R, Deligniere, A., Gazula. V.-R., Brown, M.R., Longouet, M., Chen, H., Kronengold, J., Abhyankar, A., Kaminska, A., Boddaert, N., Casanova, J.-L., Desguerre, I., Munnich, A., Dulac, O., Kaczmarek, L.K., Colleaux, L and Nabbout, R. De novo gain of function KCNT1 channel mutations cause developmental arrest and seizures in malignant migrating partial seizures of infancy, Nature Genetics, 44: 1255-1259, 2012. PMCID: PMC 3687547
  • Brown, M.R., Kronengold, J., Gazula, V.-R., Chen, Y., Strumbos, J.G., Sigworth, F.J., Navaratnam, D. and Kaczmarek, L.K. The fragile X mental retardation protein controls gating of the sodium-activated potassium channel, Slack, Nature Neuroscience, 13: 819–821, 2010. PMCID: PMC 2893252
  • Kaczmarek LK. Non-conducting functions of ion channels. Nature Rev Neurosci, 7:761-771, 2006.



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