Stephen M Strittmatter MD, PhD

Vincent Coates Professor of Neurology and Professor of Neurobiology; Director, Cellular Neuroscience, Neurodegeneration and Repair; Director, Memory Disorders Clinic

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Neuroscience | Molecular Cell Biology, Genetics and Development

Yale Medical Group

Office of Student ResearchProgram in Cellular Neuroscience, Neurodegeneration and RepairInterdepartmental Neuroscience ProgramNeurobiology: Kavli Institute for Neuroscience; Strittmatter LabNeurology: Alzheimer's Disease/Dementia and Neuro-degenerative DisordersNational Gaucher Disease Treatment Center

Research Interests

Axon Guidance; Axon Regeneration; Spinal Cord Injury; Molecular Biology; Stroke; Neurodegenerative Disease; Alzheimer's Disease; Fronto-Temporal Dementia more...


  • AB, Harvard College, 1980
  • M.D., Johns Hopkins University, 1986
  • Ph.D., Johns Hopkins University, 1986

Selected Publications

  • Kaufman AC, Salazar SV, Haas LT, Yang J, Kostylev MA, Jeng AT, Robinson SA, Gunther EC, van Dyck CH, Nygaard HB, Strittmatter SM. Fyn inhibition rescues established memory and synapse loss in Alzheimer mice. Ann Neurol. 2015 Feb 23. doi: 10.1002/ana.24394.
  • Um JW, Kaufman AC, Kostylev M, Heiss JK, Stagi M, Takahashi H, Kerrisk ME, Vortmeyer A, Wisniewski T, Koleske AJ, Gunther EC, Nygaard HB, Strittmatter SM. Metabotropic Glutamate Receptor 5 is a Co-Receptor for Alzheimer Aß Oligomer Bound to Cellular Prion Protein. Neuron, 79:887-902 (2013).
  • Akbik FV, Bhagat SM, Patel PR, Cafferty WB, Strittmatter SM. Anatomical plasticity of adult brain is titrated by nogo receptor 1. Neuron. 6:859-866 (2013).



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