Satinder Kaur Singh, PhD

Assistant Professor of Cellular And Molecular Physiology

Departments & Organizations

Cellular & Molecular Physiology

Faculty Research

Interdepartmental Neuroscience Program

Structural Biology

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Biochemistry, Biophysics and Structural Biology: Membrane Biology and Motion; Neurobiology | Molecular Medicine, Pharmacology, and Physiology: Ion Channels, Pumps and Transporters; Neurobiology, Neural Networks and Neuropharmacology; Receptors and Signal Transduction; Structural Biology

Office of Cooperative Research


Satinder was born in Boston, MA and moved, as a teenager, to Minneapolis, MN, with her family. She received her doctoral degree in Biochemistry & Molecular Biophysics from the University of Minnesota – Twin Cities, supported by an HHMI Predoctoral Fellowship. She has had a long-standing interest in the molecular mechanisms of neuropsychiatric disease, particularly in the role that the biogenic amines play. As a postdoctoral fellow, she combined her knowledge of neuropsychopharmacology and enzymology with X-ray crystallography to develop molecular models of transport and inhibition for LeuT, a bacterial orthologue of neurotransmitter sodium symporters (NSS). At Yale, Satinder has been concentrating on eukaryotic NSS members, specifically those that transport the biogenic amines serotonin (SERT) and dopamine (DAT).

Education & Training

PhD University of Minnesota (2002)
BS University of Minnesota (1995)
Postdoctoral Fellow Oregon Health and Science University
Postdoctoral Fellow Columbia University

Honors & Recognition

  • NARSAD Independent Investigator AwardBrain and Behavior Research Foundation (2015)

  • Sloan Research Fellowship AwardAlfred P. Sloan Foundation (2012)

  • Goodman & Gilman Yale Scholar AwardYale University School of Medicine (2010)

  • NIH/NIMH K99/R00 "Pathway to Independence Award"National Institutes of Health (2008)

  • NIH/NINDS Individual NRSA Postdoctoral FellowshipNational Institutes of Health (2003)

  • NSF Graduate Research Fellowship (declined)National Science Foundation (1997)

  • HHMI Predoctoral FellowshipHoward Hughes Medical Institute (1997)

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Contact Info

Satinder Kaur Singh, PhD
Office Location
Sterling Hall of Medicine, B-Wing
333 Cedar Street, Ste Room SHM BE11A

New Haven, CT 06510
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Mailing Address
333 Cedar Street, SHM B147
P.O. Box 208026

New Haven, CT 06520
Research Image 1

Crystal structure of LeuT, a bacterial orthologue of the serotonin transporter, complexed with the tricyclic antidepressant clomipramine