Sandy Chang, MD, PhD

Professor of Laboratory Medicine and Molecular Biophysics and Biochemistry; Associate Director, Molecular Diagnostics Laboratory

Departments & Organizations

Laboratory Medicine: Molecular Diagnostics

Office of Student Research


Radiobiology & Radiotherapy

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Biochemistry, Biophysics and Structural Biology: DNA Dynamics | Molecular Medicine, Pharmacology, and Physiology: Cancer Biology and Therapeutics; Genetics, Genomics and Proteomics; Stem Cell Biology

Yale Medical Group


Dr. Chang graduated with a BS from Yale College in 1988, and obtained his MD from Cornell University Medical College and his PhD from Rockefeller University in 1997. He completed residency in Clinical Pathology at the Brigham and Women's Hospital, and did his postdoctoral fellowship with Dr. Ronald DePinho at the Dana Farber Cancer Institute, Harvard Medical School. He was an Assistant and then Associate Professor in the Department of Genetics, MD Anderson Cancer Center, before joining the faculty at Yale Medical School as a tenured Associate Professor in 2010. Dr. Chang's research interests focuses on how telomeres, protein/DNA structures at the ends of chromosomes, are properly maintained to protect chromosome ends from engaging a DNA damage response.

Dr. Chang is the recipient of numerous awards, including those from the Howard Hughes Medical Institute, the Ellsion Medical Foundation, the Sidney Kimmel Foundation for Cancer Research, and the Ellis Benson Award from the Academy of Clinical Laboratory Physicians and Scientists. He was elected into the American Society of Clinical Investigation in 2009.

Education & Training

MD Cornell University Medical College (1997)
PhD Rockefeller University (1996)
BS Yale University (1988)
Resident Brigham & Women's Hospital
Resident Brigham & Women's Hospital

Honors & Recognition

  • Election into the American Society of Clinical InvestigationAmerican Society of Clinical Investigation (2009)

  • Ellis Benson AwardAcademy of Clinical Laboratory Physicians and Scientists (2007)

  • Sidney Kimmel Foundation for Cancer Research Scholar AwardSidney Kimmel Foundation (2005)

  • New Scholar in Aging AwardEllison Medical Foundation (2001)

International Activity

  • Invited speaker to many international conferences (2002 - 2011)

    Invited speaker to many international conferences

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Contact Info

Sandy Chang, MD, PhD
Patient Care Locations
Clinic Building
789 Howard Avenue

New Haven, CT 06519
Yale Laboratory MedicineYale-New Haven Hospital
20 York Street, Wing North Pavilion Fl 8th Floor Ste Apheresis

New Haven, CT 06510
Mailing Address
PO Box 208035
New Haven, CT 06520-8035