Demetrios Braddock MD, PhD

Associate Professor of Pathology; Medical Director, Precipio Diagnostics

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Medicine, Pharmacology, and Physiology | Biochemistry, Biophysics and Structural Biology

Cancer Center, Yale: Prostate and Urologic Cancers Program | Hematology Program | Cancer Genetics & Genomics

Structural Biology

Pathology: Surgical Pathology: Hematopathology | Braddock Lab

Gene Regulation and Functional Genomics


Research Interests

Structural biology; Hematopathology; Genitourinary Pathology more...


Education

  • Ph.D., University of Chicago, 1994
  • M.D., University of Chicago Pritzker School of Medicine, 1996

Selected Publications

  • Albright, R.A., Ornstein, D.L., Cao, W., Chang, W.C., Robert, D., Tehan, M., Stabach, P. R., Hoyer, D., Liu, L., Yang, G., De La Cruz, E. M., Braddock, D.T., “The Molecular Basis of Purinergic Signal Metabolism by Ecto-Nucleotide Phosphatase/Phosphodiesterases 4 and 1 and Implications in Stroke” (2013) J. Biol. Chem., Dec 12 epub ahead of print, doi: 10.1074/jbc.M113.505867
  • Albright, R.A., Chang, W.C., Robert, D., Ornstein, D.L., Cao, W., Redick, M.E., Young, J.I., De La Cruz, E. M., Braddock, D.T., “NPP4 is a procoagulant enzyme on the surface of vascular endothelium” Blood, (2012) 120:4432-4440.
  • Saunders, L. P., Wenxiang Cao, W., Chang, W. C., Albright, W.A., Demetrios T. Braddock, D. T.,* De La Cruz, E.M.*, “Kinetic Analysis of Autotaxin Reveals Substrate-specific Catalytic Pathways and a Mechanism for Lysophosphatidic Acid Distribution” (2011) Journal of Biological Chemistry, Aug 26;286(34):30130-41.

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