Jacob V.P. Eswarakumar Ph.D.

Associate Professor of Orthopaedics and Rehabilitation and Assistant Professor of Pharmacology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Medicine, Pharmacology, and Physiology | Biochemistry, Biophysics and Structural Biology

Office of Student ResearchPharmacologyOrthopaedics and Rehabilitation

Research Interests

Fibroblast Growth Factor Receptors (FGFRs) more...


  • Ph.D., Madurai Kamaraj University, 1999

Selected Publications

  • Eswarakumar VP and Schlessinger J. Skeletal overgrowth is mediated by deficiency in a specific isoform of fibroblast growth factor receptor-3. Proc Natl Acad Sci U S A. 104(10):3937-42 (2007)
  • Fox MA, Sanes JR, Borza D, Eswarakumar VP, Fassler R, Hudson B, John SW, Ninomiya Y, Pedchenko V, Rheault M, Sado Y, Segal Y, Werle MJ and Umemori H. Distinct target-derived signals organize formation, maturation and maintenance of motor nerve terminals. Cell 129(1):179-93 (2007)
  • Eswarakumar VP, Özcan F, Lew ED, Bae JH, Tomé F, Booth CJ, Adams DJ, Lax I, and Schlessinger J. Attenuation of signaling pathways stimulated by pathologically activated FGFR2 mutants prevents craniosynostosis. Proc Natl Acad Sci U S A. 103 (49), 18063-8 (2006)



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