Tobias Walther PhD
Associate Professor of Cell Biology
Departments & Organizations
Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development: Cytoskeleton and Cell Morphogenesis; Genetics and Genomics | Biochemistry, Biophysics and Structural Biology: Cell Cycle and Signal Transduction; Membrane Biology and Motion
Cell Biology
Research Interests
Organelle homeostasis; Plasma membrane organization; Lipid metabolism; Lipid Droplets; Eisosomes; Sphingolipid metabolism; Systematic genetics; RNAi screening; Mass-spectrometry based proteomics more...
Education
- Ph.D., European Molecular Biology Laboratorium (EMBL), 2002
Selected Publications
- Krahmer N, Guo Y, Wilfling F, Hilger M, Lingrell S, Heger K, Newman HW, Schmidt-Supprian M, Vance DE, Mann M, Farese RV Jr, Walther TC. Phosphatidylcholine Synthesis for Lipid Droplet Expansion Is Mediated by Localized Activation of CTP:Phosphocholine Cytidylyltransferase. Cell Metab.2011 Oct 5;14(4):504-15.
- Farese, R.V. † and Walther, T.C†. Lipid Droplets finally get a little R-E-S-P-E-C-T. Cell (2009), 139: 855-860.
- Berchtold, D., and Walther, T.C. †: TORC2 plasma membrane localization is essential for cell viability and restricted to a distinct domain, Mol. Biol. of the Cell, (2009), 20:1565-75.
