Children's Mental Health Studies Enrolling at Yale

If your child is 8 to 13 years of age and is irritable or easily frustrated, you and your child can play an important role in research by volunteering for a free and confidential study. We are looking at irritability and frustration utilizing various procedures, e.g. fMRI (functional Magnetic Resonance Imaging), measuring physiological data (e.g. heart rate), questionnaires, and interviews. The aims of the study are to identify brain mechanisms and social and environmental factors that predict irritability and its changes over two years.

Compensation up to $660.

To learn more or see if you are eligible to participate, call 203-479-0276 or email: affectiveyouth@yale.edu

Sponsored by National Institutes of Health (NIH); HIC # 2000038262

Yale is conducting a study to examine the safety, efficacy, response predictors, and post treatment trajectory of adolescents (13–17 years old) with treatment-resistant depression and high suicide risk following a conservative repeat dosing Ketamine infusion paradigm compared to an active control, Midazolam. Those who are randomized to Midazolam and remain ill have the option to cross-over to Ketamine in the open phase.

All participants will be followed closely for 4 months post-treatment and treated with standard of care depression treatment (medication management and cognitive behavioral therapy). Brain-based predictors of anti-suicidal responses will be assessed via connectome predictive modeling and examining functional brain circuits via fMRI before and after treatment.

To learn more about how this study may benefit your patients, contact Brooke Rivera, Clinical Coordinator, Yale Pediatric Depression Lab at (203) 974-2241 or email PediDepression@yale.edu.

Sponsored by the National Institute of Health; HIC# 200029003

Pro-Net Study

If your child is between the ages of 12 and 18 and has recently experienced changes in their thinking, behavior, or experiences, they may qualify for this study. These changes include confusion between reality and imagination, feeling a lack of control over your thoughts or ideas, being suspicious or paranoid, experiencing unreal sensations like hearing sounds or seeing things that aren't there, and having difficulty communicating clearly.

Participants in this study will undergo an initial screening visit, 2 MRI scans, and 2 sets of blood work. Additionally, they will be asked questions about their experiences and emotional well-being.

Total compensation of up to $1000 is provided.

To inquire further or determine eligibility for participation, please contact us at 203-200-8997 or email pronetstudy@yale.edu.

Sponsored by National Institute of Mental Health (NIMH); HIC# 2000029159

If your child is 10-16 years old with chronic tics, they may be eligible to receive neurofeedback treatment. We use a form of neurofeedback that involves monitoring brain activity via fMRI. The purpose of this study is to determine if our neurofeedback intervention can reduce tic symptoms and improve our understanding of Tourette Syndrome.

Participation can result in compensation up to $880.

If you and your child are interested in participating in this study, please click here.

If you have any further questions or concerns, please contact us at Hampson.lab@yale.edu, or (203)-737-6055.

Sponsored by National Institute of Mental Health, Department of Human Health Services HIC #: 2000033043