Saseong Lee
Associate Research ScientistCards
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Research
Publications
2026
The therapeutic effects of the VEGF decoy receptor fusion protein VEGF-Grab in chronic inflammatory diseases
Lee Y, Lee H, Lim H, Shin J, Yang H, Lee S, Mercadante G, Cicatiello V, De Falco S, Kim H, Kim C, Lee S, Kim Y, Yoo S, Lee S, Kim W. The therapeutic effects of the VEGF decoy receptor fusion protein VEGF-Grab in chronic inflammatory diseases. EBioMedicine 2026, 126: 106216. PMID: 41861515, PMCID: PMC13015212, DOI: 10.1016/j.ebiom.2026.106216.Peer-Reviewed Original Research
2025
Asthma Alleviation by Ginsenoside Rb1 via Promotion of Treg Proliferation and Inflammatory T Cell Inhibition
Choi S, Yoo S, Ji K, Jung D, Lee S, Lee K, Kim K, Lee J, Jung M, Pyun B, Hur J, Choi J, Rhee C, Kim W, Kim T. Asthma Alleviation by Ginsenoside Rb1 via Promotion of Treg Proliferation and Inflammatory T Cell Inhibition. Allergy 2025, 80: 1647-1668. PMID: 40251907, PMCID: PMC12186593, DOI: 10.1111/all.16551.Peer-Reviewed Original Research
2024
The acute phase reactant orosomucoid-2 directly promotes rheumatoid inflammation
Kim K, Lee K, Lee S, Hong B, Yun H, Park Y, Yoo S, Kim W. The acute phase reactant orosomucoid-2 directly promotes rheumatoid inflammation. Experimental & Molecular Medicine 2024, 56: 890-903. PMID: 38556552, PMCID: PMC11058272, DOI: 10.1038/s12276-024-01188-0.Peer-Reviewed Original ResearchNuclear receptor coactivator 6 is a critical regulator of NLRP3 inflammasome activation and gouty arthritis
Lee K, Hong B, Lee S, Lee N, Kim S, Kim D, Kim W. Nuclear receptor coactivator 6 is a critical regulator of NLRP3 inflammasome activation and gouty arthritis. Cellular & Molecular Immunology 2024, 21: 227-244. PMID: 38195836, PMCID: PMC10902316, DOI: 10.1038/s41423-023-01121-x.Peer-Reviewed Original Research
2023
Identification of MYH9 as a key regulator for synoviocyte migration and invasion through secretome profiling
Lee S, Choi E, Chae S, Koh J, Choi Y, Kim J, Yoo S, Hwang D, Kim W. Identification of MYH9 as a key regulator for synoviocyte migration and invasion through secretome profiling. Annals Of The Rheumatic Diseases 2023, 82: 1035-1048. PMID: 37188496, PMCID: PMC10359537, DOI: 10.1136/ard-2022-223625.Peer-Reviewed Original ResearchRole of high-temperature requirement serine protease A 2 in rheumatoid inflammation
Jeong G, Nam M, Hur W, Heo S, Lee S, Choi E, Park J, Park Y, Kim W, Rhim H, Yoo S. Role of high-temperature requirement serine protease A 2 in rheumatoid inflammation. Arthritis Research & Therapy 2023, 25: 96. PMID: 37287073, PMCID: PMC10246393, DOI: 10.1186/s13075-023-03081-z.Peer-Reviewed Original Research
2021
Genetic deficiency of nuclear factor of activated T cells 5 attenuates the development of osteoarthritis in mice
Lee J, Lee J, Lee S, Yoo S, Kim K, Kim W, Cho C, Yoon C. Genetic deficiency of nuclear factor of activated T cells 5 attenuates the development of osteoarthritis in mice. Joint Bone Spine 2021, 89: 105273. PMID: 34537377, DOI: 10.1016/j.jbspin.2021.105273.Peer-Reviewed Original Research
2020
Development of Monitoring System for Assessing Rheumatoid Arthritis within 5 Minutes Using a Drop of Bio-Fluids
Koh J, Lee S, Kim H, Lee K, Lee C, Yoo S, Lee N, Kim W. Development of Monitoring System for Assessing Rheumatoid Arthritis within 5 Minutes Using a Drop of Bio-Fluids. Journal Of Clinical Medicine 2020, 9: 3499. PMID: 33138147, PMCID: PMC7692111, DOI: 10.3390/jcm9113499.Peer-Reviewed Original ResearchAngiogenic cytokines can reflect the synovitis severity and treatment response to biologics in rheumatoid arthritis
Kim J, Kong J, Lee S, Yoo S, Koh J, Jin J, Kim W. Angiogenic cytokines can reflect the synovitis severity and treatment response to biologics in rheumatoid arthritis. Experimental & Molecular Medicine 2020, 52: 843-853. PMID: 32461558, PMCID: PMC7272442, DOI: 10.1038/s12276-020-0443-8.Peer-Reviewed Original Research
2019
Placental growth factor regulates the generation of TH17 cells to link angiogenesis with autoimmunity
Yoo S, Kim M, Kang M, Kong J, Kim K, Lee S, Hong B, Jeong G, Lee J, Shin M, Kim Y, Apicella I, Cicatiello V, De Falco S, Yoon C, Cho C, Ryoo Z, Lee S, Kim W. Placental growth factor regulates the generation of TH17 cells to link angiogenesis with autoimmunity. Nature Immunology 2019, 20: 1348-1359. PMID: 31406382, DOI: 10.1038/s41590-019-0456-4.Peer-Reviewed Original ResearchAnimalsArthritis, ExperimentalAutoimmunityCell DifferentiationCells, CulturedEncephalomyelitis, Autoimmune, ExperimentalInterleukin-17Interleukin-6Lymphocyte ActivationMiceMice, Inbred C57BLMice, Inbred DBAMice, KnockoutNeovascularization, PathologicPlacenta Growth FactorSTAT3 Transcription FactorT-Lymphocytes, RegulatoryTh17 Cells
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