Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsRenata Belfort De Aguiar, MD, PhD
Associate Professor AdjunctAbout
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Titles
Associate Professor Adjunct
Biography
Renata Belfort De Aguiar, MD, PhD, treats diabetes and transplant patients and has a special focus on the relationship between obesity and diabetes.
“Obesity is one of the leading preventable causes of death in the United States and one of the major risk factors for type 2 diabetes,” says Dr. Belfort De Aguiar, who is an assistant professor of medicine (endocrinology) at Yale School of Medicine. She points out that the reasons why people eat poorly is still largely misunderstood. “My research looks into the influence of changes in circulating blood glucose on the activation of brain regions associated with the desire for and intake of high-calorie foods in obese patients with type 2 diabetes.”
Research is driving treatment, and Dr. Belfort De Aguiar likes to reassure patients by telling them about the ever-expanding array of clinical and technical support for diabetes, including new medications and devices.
Appointments
Endocrinology
Associate Professor AdjunctPrimary
Other Departments & Organizations
- Diabetes Center
- Diabetes Research Center
- Endocrinology
- Internal Medicine
- MR Core
- Obesity Research Working Group
Education & Training
- Residency
- Boston University (2008)
- PhD
- Federal University of Rio de Janeiro (2004)
- MS
- Federal University of Rio de Janeiro (2000)
- MD
- Federal University of Rio de Janeiro (1993)
Research
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Overview
Medical Research Interests
ORCID
0000-0002-4357-0447
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Rajita Sinha, PhD
Dongju Seo, PhD
Janice Jin Hwang, MD
Lisa Parikh
Former YSMRobert Sherwin
Former YSMTodd Constable, PhD
Obesity
Diabetes Mellitus, Type 2
Diabetes Mellitus
Diabetes Mellitus, Type 1
Publications
2025
Association of Insulin Resistance and Insulin Secretion Indices and Glucose Metrics From Continuous Glucose Monitoring in People With Obesity.
Belfort-DeAguiar R, Yeckel C, Elshafie A, Comarella A, Hwang J. Association of Insulin Resistance and Insulin Secretion Indices and Glucose Metrics From Continuous Glucose Monitoring in People With Obesity. Diabetes Care 2025, 49: 152-160. PMID: 41418028, PMCID: PMC12719714, DOI: 10.2337/dc25-1395.Peer-Reviewed Original ResearchCitationsAltmetricMeasurement of brain glucose metabolism in obesity and diabetes
Hwang J, Bini J, Belfort-DeAguiar R. Measurement of brain glucose metabolism in obesity and diabetes. Diabetologia 2025, 68: 1879-1888. PMID: 40711543, PMCID: PMC12361331, DOI: 10.1007/s00125-025-06491-7.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsAltmetricPharmacotherapies for Binge Eating Disorder: Systematic Review and Network Meta‐Analysis
Costa G, Assunção B, Belfort‐DeAguiar R, Nunes J. Pharmacotherapies for Binge Eating Disorder: Systematic Review and Network Meta‐Analysis. Obesity Reviews 2025, 26: e13936. PMID: 40344489, DOI: 10.1111/obr.13936.Peer-Reviewed Original ResearchCitationsAltmetric
2024
Low‐calorie diet‐induced weight loss is associated with altered brain connectivity and food desire in obesity
Hoang H, Lacadie C, Hwang J, Lam K, Elshafie A, Rosenberg S, Watt C, Sinha R, Constable R, Savoye M, Seo D, Belfort‐DeAguiar R. Low‐calorie diet‐induced weight loss is associated with altered brain connectivity and food desire in obesity. Obesity 2024, 32: 1362-1372. PMID: 38831482, PMCID: PMC11211061, DOI: 10.1002/oby.24046.Peer-Reviewed Original ResearchCitationsAltmetric
2023
A global research priority agenda to advance public health responses to fatty liver disease
Lazarus J, Mark H, Allen A, Arab J, Carrieri P, Noureddin M, Alazawi W, Alkhouri N, Alqahtani S, Arrese M, Bataller R, Berg T, Brennan P, Burra P, Castro-Narro G, Cortez-Pinto H, Cusi K, Dedes N, Duseja A, Francque S, Hagström H, Huang T, Wajcman D, Kautz A, Kopka C, Krag A, Miller V, Newsome P, Rinella M, Romero D, Sarin S, Silva M, Spearman C, Tsochatzis E, Valenti L, Villota-Rivas M, Zelber-Sagi S, Schattenberg J, Wong V, Younossi Z, Livers H, Lazarus J, Mark H, Allen A, Arab J, Carrieri P, Noureddin M, Alazawi W, Alkhouri N, Alqahtani S, Arrese M, Bataller R, Berg T, Brennan P, Burra P, Castro-Narro G, Cortez-Pinto H, Cusi K, Dedes N, Duseja A, Francque S, Hagström H, Huang T, Wajcman D, Kautz A, Kopka C, Krag A, Miller V, Newsome P, Rinella M, Romero D, Sarin S, Silva M, Spearman C, Tsochatzis E, Valenti L, Villota-Rivas M, Zelber-Sagi S, Schattenberg J, Wong V, Younossi Z, Aberg F, Adams L, Al-Naamani K, Albadawy R, Alexa Z, Allison M, Alnaser F, Alswat K, Alvares-da-Silva M, Alvaro D, Alves-Bezerra M, Andrade R, Anstee Q, Awuku Y, Baatarkhuu O, Baffy G, Bakieva S, Bansal M, Barouki R, Batterham R, Behling C, Belfort-DeAguiar R, Berzigotti A, Betel M, Bianco C, Bosi E, Boursier J, Brunt E, Bugianesi E, Byrne C, Cabrejos M, Caldwell S, Carr R, Fernández M, Castera L, Castillo-López M, Caussy C, Cerda-Reyes E, Ceriello A, Chan W, Chang Y, Charatcharoenwitthaya P, Chavez-Tapia N, Chung R, Colombo M, Coppell K, Cotrim H, Craxi A, Crespo J, Dassanayake A, Davidson N, De Knegt R, de Ledinghen V, Demir M, Desalegn H, Diago M, Dillon J, Dimmig B, Dirac M, Dirchwolf M, Dufour J, Dvorak K, Ekstedt M, El-Kassas M, Elsanousi O, Elsharkawy A, Elwakil R, Eskridge W, Eslam M, Esmat G, Fan J, Ferraz M, Flisiak R, Fortin D, Fouad Y, Freidman S, Fuchs M, Gadano A, Gastaldelli A, Geerts A, Geier A, George J, Gerber L, Ghazinyan H, Gheorghe L, Kile D, Girala M, Bee G, Goossens N, Graupera I, Grønbæk H, Hamid S, Hebditch V, Henry Z, Hickman I, Hobbs L, Hocking S, Hofmann W, Idilman R, Iruzubieta P, Isaacs S, Isakov V, Ismail M, Jamal M, Jarvis H, Jepsen P, Jornayvaz F, Sudhamshu K, Kakizaki S, Karpen S, Kawaguchi T, Keating S, Khader Y, Kim S, Kim W, Kleiner D, Koek G, Komas N, Kondili L, Koot B, Korenjak M, Kotsiliti E, Koulla Y, Kugelmas C, Kugelmas M, Labidi A, Lange N, Lavine J, Lazo M, Leite N, Lin H, Lkhagvaa U, Long M, Lopez-Jaramillo P, Lozano A, Macedo M, Malekzadeh R, Marchesini G, Marciano S, Martinez K, Vázquez S, Mateva L, Mato J, Nlombi C, McCary A, McIntyre J, McKee M, Mendive J, Mikolasevic I, Miller P, Milovanovic T, Milton T, Moreno-Alcantar R, Morgan T, Motala A, Muris J, Musso C, Nava-González E, Negro F, Nersesov A, Neuschwander-Tetri B, Nikolova D, Norris S, Novak K, Ocama P, Ong J, Ong-Go A, Onyekwere C, Padilla M, Pais R, Pan C, Panduro A, Panigrahi M, Papatheodoridis G, Paruk I, Patel K, Gonçalves C, Figueroa M, Pérez-Escobar J, Pericàs J, Perseghin G, Pessoa M, Petta S, de Oliveira C, Prabhakaran D, Pyrsopoulous N, Rabiee A, Ramji A, Ratziu V, Ravendhran N, Ray K, Roden M, Romeo S, Romero-Gómez M, Rotman Y, Rouabhia S, Rowe I, Sadirova S, Alkhatry M, Salupere R, Satapathy S, Schwimmer J, Sebastiani G, Seim L, Seki Y, Serme A, Shapiro D, Sharvadze L, Shaw J, Shawa I, Shenoy T, Shibolet O, Shimakawa Y, Shubrook J, Singh S, Sinkala E, Skladany L, Skrypnyk I, Song M, Sookoian S, Sridharan K, Stefan N, Stine J, Stratakis N, Sheriff D, Sundaram S, Svegliati-Baroni G, Swain M, Tacke F, Taheri S, Tan S, Tapper E, Targher G, Tcaciuc E, Thiele M, Tiniakos D, Tolmane I, Torre A, Torres E, Treeprasertsuk S, Trenell M, Turcan S, Turcanu A, Valantinas J, van Kleef L, Velasco J, Vesterhus M, Vilar-Gomez E, Waked, Wattacheril J, Wedemeyer H, Wilkins F, Willemse J, Wong R, Yilmaz Y, Yki-Järvinen H, Yu M, Yumuk V, Zeybel M, Zheng K, Zheng M. A global research priority agenda to advance public health responses to fatty liver disease. Journal Of Hepatology 2023, 79: 618-634. PMID: 37353401, DOI: 10.1016/j.jhep.2023.04.035.Peer-Reviewed Original ResearchCitationsAltmetric
2022
Approach to the Patient With Nonalcoholic Fatty Liver Disease
Belfort-DeAguiar R, Lomonaco R, Cusi K. Approach to the Patient With Nonalcoholic Fatty Liver Disease. The Journal Of Clinical Endocrinology & Metabolism 2022, 108: 483-495. PMID: 36305273, DOI: 10.1210/clinem/dgac624.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsAltmetric
2021
PPAR‐γ‐induced changes in visceral fat and adiponectin levels are associated with improvement of steatohepatitis in patients with NASH
Gastaldelli A, Sabatini S, Carli F, Gaggini M, Bril F, Belfort‐DeAguiar R, Positano V, Barb D, Kadiyala S, Harrison S, Cusi K. PPAR‐γ‐induced changes in visceral fat and adiponectin levels are associated with improvement of steatohepatitis in patients with NASH. Liver International 2021, 41: 2659-2670. PMID: 34219361, PMCID: PMC9290929, DOI: 10.1111/liv.15005.Peer-Reviewed Original ResearchCitationsAltmetricImplementing a pharmacist-led transition of care model for posttransplant hyperglycemia
Do V, Haakinson D, Belfort-DeAguiar R, Cohen E. Implementing a pharmacist-led transition of care model for posttransplant hyperglycemia. American Journal Of Health-System Pharmacy 2021, 78: 1207-1215. PMID: 33821878, PMCID: PMC8083386, DOI: 10.1093/ajhp/zxab151.Peer-Reviewed Original ResearchCitationsAltmetric
2019
Differential resting state connectivity responses to glycemic state in type 1 diabetes
Parikh L, Seo D, Lacadie C, Belfort-DeAguiar R, Groskreutz D, Hamza M, Dai F, Scheinost D, Sinha R, Constable R, Sherwin R, Hwang J. Differential resting state connectivity responses to glycemic state in type 1 diabetes. The Journal Of Clinical Endocrinology & Metabolism 2019 DOI: 10.1210/jcem/dgz004.Peer-Reviewed Original ResearchCitationsIn a Free-Living Setting, Obesity Is Associated With Greater Food Intake in Response to a Similar Premeal Glucose Nadir
Kim J, Lam W, Wang Q, Parikh L, Elshafie A, Sanchez-Rangel E, Schmidt C, Li F, Hwang J, Belfort-DeAguiar R. In a Free-Living Setting, Obesity Is Associated With Greater Food Intake in Response to a Similar Premeal Glucose Nadir. The Journal Of Clinical Endocrinology & Metabolism 2019, 104: 3911-3919. PMID: 31087061, PMCID: PMC6667277, DOI: 10.1210/jc.2019-00240.Peer-Reviewed Original ResearchCitationsAltmetric
Academic Achievements & Community Involvement
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Activities
activity Journal of Clinical Endocrinology and Metabolism
2013 - PresentJournal ServiceRevieweractivity Archives of Endocrinology and Metabolism
2015 - PresentJournal ServiceRevieweractivity Diabetes, Obesity and Metabolism
2017 - PresentJournal ServiceRevieweractivity International Journal of Obesity
2018 - PresentJournal ServiceRevieweractivity Section of Endocrinology Gender Equity Task Force
2018 - PresentCommitteesCommittee Member
Honors
honor Mentor-Based Minority Postdoctoral Fellowship Program
08/01/2007National AwardAmerican Diabetes Assoc. / Takeda PharmaceuticalsDetailsUnited States
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