Holly Grossetta Nardini, AHIP
Associate DirectorCards
About
Research
Publications
2025
Improving peer review of systematic reviews and related review types by involving librarians and information specialists as methodological peer reviewers: a randomised controlled trial
Rethlefsen M, Schroter S, Bouter L, Kirkham J, Moher D, Ayala A, Blanco D, Brigham T, Nardini H, Kirtley S, Nyhan K, Townsend W, Zeegers M. Improving peer review of systematic reviews and related review types by involving librarians and information specialists as methodological peer reviewers: a randomised controlled trial. BMJ Evidence-Based Medicine 2025, 30: 241-249. PMID: 40074237, PMCID: PMC12320611, DOI: 10.1136/bmjebm-2024-113527.Peer-Reviewed Original ResearchRisk of biasQuality of reportingIntervention groupSystematic reviewPeer reviewMonths post-studyRandomised controlled trialsSystematic review searchControl groupReview typesPRISMA itemsInformation specialistsPost-peer reviewImprove peer reviewGroup allocationReview searchPost-studyInclusion criteriaStudy enrollmentSecondary outcomesJournal peer review processControlled TrialsPrimary outcomePeer review processAdequate reportingSystematic review and meta-analysis of the genetics of peripheral arterial disease
Chaar C, Kim T, Alameddine D, DeWan A, Guzman R, Dardik A, Nardini H, Wallach J, Kullo I, Murray M. Systematic review and meta-analysis of the genetics of peripheral arterial disease. Journal Of Vascular Surgery 2025, 81: a13-a14. DOI: 10.1016/j.jvs.2024.10.063.Peer-Reviewed Original Research
2023
Systematic review and meta-analysis of the genetics of peripheral arterial disease
Ochoa Chaar C, Kim T, Alameddine D, DeWan A, Guzman R, Dardik A, Grossetta Nardini H, Wallach J, Kullo I, Murray M. Systematic review and meta-analysis of the genetics of peripheral arterial disease. JVS Vascular Science 2023, 5: 100133. PMID: 38314202, PMCID: PMC10832467, DOI: 10.1016/j.jvssci.2023.100133.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsGenome-wide association studiesDNA variantsWide association studyRecent genome-wide association studiesSmall candidate gene studiesCandidate gene studiesGWAS studiesCandidate genesAssociation studiesGene studiesGenetic researchGeneticsOnly variantVariantsHepatic lipaseGenesProgressionSignificant variation
2021
Evidence synthesis papers would benefit from segmented peer review
Nyhan K, Nardini H. Evidence synthesis papers would benefit from segmented peer review. Translational Oncology 2021, 14: 101060. PMID: 33706230, PMCID: PMC7944096, DOI: 10.1016/j.tranon.2021.101060.Commentaries, Editorials and Letters
2020
Information Loss in Harmonizing Granular Race and Ethnicity Data: Descriptive Study of Standards
Wang K, Nardini H, Post L, Edwards T, Nunez-Smith M, Brandt C. Information Loss in Harmonizing Granular Race and Ethnicity Data: Descriptive Study of Standards. Journal Of Medical Internet Research 2020, 22: e14591. PMID: 32706693, PMCID: PMC7399950, DOI: 10.2196/14591.Peer-Reviewed Original ResearchLong-term natural history of visual acuity in eyes with choroideremia: a systematic review and meta-analysis of data from 1004 individual eyes
Shen LL, Ahluwalia A, Sun M, Young BK, Nardini H, Del Priore LV. Long-term natural history of visual acuity in eyes with choroideremia: a systematic review and meta-analysis of data from 1004 individual eyes. British Journal Of Ophthalmology 2020, 105: 271-278. PMID: 32471821, PMCID: PMC7704705, DOI: 10.1136/bjophthalmol-2020-316028.Peer-Reviewed Original ResearchConceptsBest-corrected visual acuityLong-term natural historyHorizontal translation factorPrimary endpointVisual acuityNatural historyCommon primary endpointBCVA declineYounger patientsUntreated eyesFuture trialsTreatment trialsAge 39Transition ageSystematic reviewFunction of ageIndividual eyesChoroideremiaAgeEndpointSole endpointEyesPatientsAcuityDisease biomarkersProgression of Unifocal versus Multifocal Geographic Atrophy in Age-Related Macular Degeneration A Systematic Review and Meta-analysis
Shen LL, Sun M, Grossetta Nardini HK, Del Priore LV. Progression of Unifocal versus Multifocal Geographic Atrophy in Age-Related Macular Degeneration A Systematic Review and Meta-analysis. Ophthalmology Retina 2020, 4: 899-910. PMID: 32423772, PMCID: PMC7483721, DOI: 10.1016/j.oret.2020.03.020.Peer-Reviewed Original ResearchConceptsMultifocal geographic atrophyGeographic atrophyMacular Degeneration A Systematic ReviewNonexudative age-related macular degenerationAge-related macular degenerationHorizontal translation factorPrognosis Studies toolSignificant prognostic factorsA Systematic ReviewColor fundus photographyGA growth rateMultifocal groupPrognostic factorsFundus autofluorescenceGA patientsFundus photographyEgger's testMacular degenerationStudy qualityFunnel plotSystematic reviewMeta-analysisPublication biasGA lesionsLesion perimeterLong-term Natural History of Atrophy in Eyes with Choroideremia—A Systematic Review and Meta-analysis of Individual-Level Data
Shen LL, Ahluwalia A, Sun M, Young BK, Grossetta Nardini HK, Del Priore LV. Long-term Natural History of Atrophy in Eyes with Choroideremia—A Systematic Review and Meta-analysis of Individual-Level Data. Ophthalmology Retina 2020, 4: 840-852. PMID: 32362554, PMCID: PMC7415675, DOI: 10.1016/j.oret.2020.03.003.Peer-Reviewed Original ResearchConceptsResidual retinal pigment epitheliumLong-term natural historyHorizontal translation factorFundus autofluorescenceRPE areaNatural historyUntreated eyesSystematic reviewPrognosis Studies toolRisk of biasRetinal pigment epitheliumLog-transformed areaAnatomic endpointsPatient ageRPE changesTreatment trialsDisease progressionAnatomic measuresPigment epitheliumMeta-analysisLiterature databasesIndividual eyesCross-sectional dataChoroideremiaAtrophyUpdating insights into rosiglitazone and cardiovascular risk through shared data: individual patient and summary level meta-analyses
Wallach JD, Wang K, Zhang AD, Cheng D, Grossetta Nardini HK, Lin H, Bracken MB, Desai M, Krumholz HM, Ross JS. Updating insights into rosiglitazone and cardiovascular risk through shared data: individual patient and summary level meta-analyses. The BMJ 2020, 368: l7078. PMID: 32024657, PMCID: PMC7190063, DOI: 10.1136/bmj.l7078.Peer-Reviewed Original ResearchConceptsIndividual patient-level dataCardiovascular related deathsCardiovascular riskMyocardial infarctionRelated deathsSummary-level dataHeart failureOdds ratioSystematic reviewIncreased cardiovascular riskMore myocardial infarctionsHeart failure eventsCochrane Central RegistryAcute myocardial infarctionMyocardial infarction eventsPatient-level dataRandom-effects modelWeb of ScienceAnalysis of trialsEligible trialsComposite outcomeAdverse eventsContinuity correctionControlled TrialsRosiglitazone treatmentTopographic Variation of the Growth Rate of Geographic Atrophy in Nonexudative Age-Related Macular Degeneration: A Systematic Review and Meta-analysis
Shen LL, Sun M, Khetpal S, Nardini H, Del Priore LV. Topographic Variation of the Growth Rate of Geographic Atrophy in Nonexudative Age-Related Macular Degeneration: A Systematic Review and Meta-analysis. Investigative Ophthalmology & Visual Science 2020, 61: 2. PMID: 31995152, PMCID: PMC7205189, DOI: 10.1167/iovs.61.1.2.Peer-Reviewed Original Research
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