Emily J. Gilmore, MD, FNCS, FACNS
Professor of Neurology & NeurosurgeryCards
Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileAdditional Titles
Clinical Chief, Division of Neurocritical Care and Emergency Neurology, Neurology
Co-director, Critical Care EEG Program, Neurology
Director, Neurosciences Intensive Care Unit, Neurology
Co-director, Neuorotrauma, Neurology & Neurosurgery
Contact Info
Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileAdditional Titles
Clinical Chief, Division of Neurocritical Care and Emergency Neurology, Neurology
Co-director, Critical Care EEG Program, Neurology
Director, Neurosciences Intensive Care Unit, Neurology
Co-director, Neuorotrauma, Neurology & Neurosurgery
Contact Info
Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileAdditional Titles
Clinical Chief, Division of Neurocritical Care and Emergency Neurology, Neurology
Co-director, Critical Care EEG Program, Neurology
Director, Neurosciences Intensive Care Unit, Neurology
Co-director, Neuorotrauma, Neurology & Neurosurgery
Contact Info
About
Copy Link
Titles
Professor of Neurology & Neurosurgery
Clinical Chief, Division of Neurocritical Care and Emergency Neurology, Neurology; Co-director, Critical Care EEG Program, Neurology; Director, Neurosciences Intensive Care Unit, Neurology; Co-director, Neuorotrauma, Neurology & Neurosurgery
Biography
Emily J. Gilmore, MD has been a member of the Division of Neurocritical Care and Emergency Neurology at the Yale School of Medicine and a neurointensivist and critical care EEG attending at Yale New Haven Hospital in Connecticut since 2012.
Dr. Gilmore completed her neurology residency and 3-year combined fellowship at Columbia University where she fostered a clinical and research interest in neuromonitoring. She was one of the first neurointensivists to become board certified in critical care EEG monitoring and was recruited to Yale to help build a state-of-the art Neuro-ICU where technology could be deployed to deliver cutting edge care for patients with acute brain injury.
Marrying her clinical and research interests was natural; she was an early recipient of the Yale Center for Clinical Investigation (YCCI) Clinical Scholars program and the American Brain Foundation Clinical Research Training Fellowship. She currently serves as the site-PI for several national neurotrauma trials and was recently awarded her first RO1 with colleagues from MGH and UTSW to link the relationship between biomarkers of secondary brain injury, treatment, and outcomes in patients with severe TBI. Her overarching research interests center on understanding and translating physiologic biomarkers obtained from invasive and noninvasive multimodal brain monitoring to individualize care that will improve outcomes for patients with acute brain injury.
Administratively, in addition to her role as Director of the Neuro-ICU and Director of Neuromonitoring, Dr. Gilmore is the co-Director of Neurotrauma. With colleagues in Neurosurgery, she is building a comprehensive multidisciplinary program that addresses the continuum of care needs, from the acute setting though rehabilitation and recovery, for patients with TBI. Additionally, she co-directs the Critical Care EEG program fellowship and program with Dr. Lawrence Hirsch, serves as the past-chair of the Critical Care EEG Monitoring Research Consortium (CCEMRC) and sits on the scientific advisory board for the NORSE institute.
Appointments
Neurology
ProfessorFully JointNeurosurgery
ProfessorFully Joint
Other Departments & Organizations
Education & Training
- Fellow
- Neurological Institute of New York at Columbia University (2012)
- Fellow
- Neurological Institute of New York at Columbia University (2010)
- Resident
- Neurological Institute of New York at Columbia University (2009)
- Chief Resident
- Neurological Institute of New York at Columbia University (2009)
- Intern
- Yale Primary Care Program (2006)
- MD
- University of New Mexico (2005)
- BS
- Vassar College (1998)
Research
Copy Link
Overview
Medical Research Interests
ORCID
0000-0002-4659-6861
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Kevin Sheth, MD
Lawrence Hirsch, MD
Rachel Beekman, MD
Guido J. Falcone, MD, ScD, MPH
Nils Petersen, MD, PhD, MSc
Charles Matouk, MD
Cerebral Hemorrhage
Subarachnoid Hemorrhage
Electroencephalography
Treatment Outcome
Critical Care
Status Epilepticus
Publications
2025
Super-Refractory Status Epilepticus Diagnosis, Management, and Prognostication: An International Survey Study.
Woodward M, Brown J, Kittner S, Badjatia N, Gilmore E, Johnson E, Morris N. Super-Refractory Status Epilepticus Diagnosis, Management, and Prognostication: An International Survey Study. Neurology Clinical Practice 2025, 15: e200520. PMID: 40917457, PMCID: PMC12413177, DOI: 10.1212/cpj.0000000000200520.Peer-Reviewed Original ResearchCitationsAltmetricImpact of Nimodipine-Induced Blood Pressure Reductions on Cerebral Autoregulation and Functional Outcome After Aneurysmal Subarachnoid Hemorrhage
Stoehr K, Bartolome D, Jayasundara S, Thinzar P, Vargas D, Kim J, Magid-Bernstein J, O’Keefe L, de Havenon A, Hebert R, Matouk C, Sheth K, Gilmore E, Ortega-Gutierrez S, Petersen N. Impact of Nimodipine-Induced Blood Pressure Reductions on Cerebral Autoregulation and Functional Outcome After Aneurysmal Subarachnoid Hemorrhage. Neurocritical Care 2025, 1-11. PMID: 40847251, DOI: 10.1007/s12028-025-02338-6.Peer-Reviewed Original ResearchCitationsAltmetricConceptsAneurysmal subarachnoid hemorrhageMean arterial pressureAssociated with worse functional outcomeBP reductionFunctional outcomesNimodipine administrationSubarachnoid hemorrhageHunt & Hess scoreBlood pressureAssociated with BP reductionSevere aneurysmal subarachnoid hemorrhageModified Fisher gradeResponse to nimodipineSensitive to nimodipineCerebral autoregulationDelayed Cerebral IschemiaBlood pressure reductionRegional oxygen saturationObservational cohort studyModified Rankin ScaleLimits of autoregulationFisher gradeHess scoreAneurysm securementNeurological outcomeNot All Temperature Control Is Equal: High-Quality Temperature Control Is Associated With Improved Outcomes Following Out-of-Hospital Cardiac Arrest
Beekman R, Nguyen C, Deng Y, Chakravartty A, Perman S, Wira C, Khosla A, Miller P, Sheth K, Greer D, Gilmore E. Not All Temperature Control Is Equal: High-Quality Temperature Control Is Associated With Improved Outcomes Following Out-of-Hospital Cardiac Arrest. Annals Of Emergency Medicine 2025 PMID: 40817896, DOI: 10.1016/j.annemergmed.2025.06.622.Peer-Reviewed Original ResearchAltmetricConceptsSingle-center studyInverse probability treatment weightsNeurological outcomeCardiac arrestOut-of-hospital cardiac arrestOut-of-hospital cardiac arrest patientsHospital dischargeSecondary outcomesTreatment weightingCerebral Performance Category scoreAssociated with improved outcomesNeuroprotective benefitsProspective multicenter studyFavorable neurologic outcomeSmall effect sizesSurvivors of cardiac arrestCardiac arrest patientsAdjunctive pharmacologic treatmentStandardized mean differenceAchievement of target temperatureHigh-quality groupHospital arrivalArrest patientsMulticenter studyClinical outcomesEarly CSF inflammatory markers after aneurysmal subarachnoid hemorrhage and their relationship to disease severity and shunt placement
Magid-Bernstein J, Yan J, Herman A, He Z, Johnson C, Beatty H, Choi R, Velazquez S, Sorensen G, Jayasundara S, Grychowski L, Amllay A, Falcone G, Kim J, Petersen N, O’Keefe L, Gilmore E, Matouk C, Sheth K, Sansing L. Early CSF inflammatory markers after aneurysmal subarachnoid hemorrhage and their relationship to disease severity and shunt placement. Journal Of Stroke And Cerebrovascular Diseases 2025, 34: 108395. PMID: 40639751, PMCID: PMC12333380, DOI: 10.1016/j.jstrokecerebrovasdis.2025.108395.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsPermanent shunt placementAneurysmal subarachnoid hemorrhage patientsGranulocyte-colony stimulating factorAneurysmal subarachnoid hemorrhageVascular endothelial growth factorCC motif chemokine ligand 2Shunt placementCerebrospinal fluidCerebrospinal fluid samplesInterleukin-6Interleukin-8Disease severityPreclinical modelsSubarachnoid hemorrhageModified Fisher scale scoresModels of CNS inflammationShunt-dependent hydrocephalusAssociated with clinical severityConcentrations of interleukin-6Post-hemorrhagic hydrocephalusMotif chemokine ligand 2Panel of cytokinesCSF inflammatory markersEndothelial growth factorCerebrospinal fluid concentrationsThe impact of pupil diameter on assessing illness severity and outcome after out-of-hospital cardiac arrest in patients with unreactive pupils
Beekman R, Chakravartty A, Nguyen C, Perman S, Wira C, Buckley R, Khosla A, Miller P, Greer D, Gilmore E. The impact of pupil diameter on assessing illness severity and outcome after out-of-hospital cardiac arrest in patients with unreactive pupils. Resuscitation 2025, 215: 110699. PMID: 40582484, DOI: 10.1016/j.resuscitation.2025.110699.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsOut-of-hospital cardiac arrestAbsent pupillary light reflexPupillary light reflexDilated pupilsPremorbid medical conditionsCardiac arrestPost-ROSCIllness severityClinical outcomesPupil sizeOut-of-hospital cardiac arrest patientsIndicator of poor prognosisHigher incidenceAssociated with poor outcomesMedical conditionsSingle-center studyPoor neurological outcomePrediction of brain deathIllness severity scoresBrain deathHigher illness severityIncidence of brain deathSpontaneous circulationQuantitative pupillometryNeurological outcomeAPOE ε4 and Risk of Intracranial Hemorrhage in Patients With Atrial Fibrillation Taking Apixaban
Clocchiatti-Tuozzo S, Rivier C, Renedo D, Huo S, de Havenon A, Hawkes M, Gilmore E, Schwamm L, Sheth K, Gill T, Falcone G. APOE ε4 and Risk of Intracranial Hemorrhage in Patients With Atrial Fibrillation Taking Apixaban. JAMA Neurology 2025, 82: 808-816. PMID: 40549373, PMCID: PMC12186128, DOI: 10.1001/jamaneurol.2025.0182.Peer-Reviewed Original ResearchAltmetricConceptsRisk of intracranial hemorrhagePopulation-based studyYears of follow-up dataApo E4Cox proportional hazards modelsAPOE e4 alleleIntracranial hemorrhageRisk prediction scoreCerebral amyloid angiopathyClinical decision-makingProportional hazards modelAtrial fibrillationIncreased risk of ICHMultivariate Cox proportional hazards modelMain OutcomesIncident intracranial hemorrhageEuropean ancestryCohort studyInclusion criteriaHistory of ischemic strokeAmyloid angiopathyE4 variantHazards modelIncreased riskE4 alleleRepolarisation abnormalities and outcomes among patients with cardiac arrest
Schenck C, Banna S, Kim N, Nguyen C, Gilmore E, Greer D, Beekman R, Miller P. Repolarisation abnormalities and outcomes among patients with cardiac arrest. European Heart Journal Acute Cardiovascular Care 2025, zuaf077. PMID: 40424593, DOI: 10.1093/ehjacc/zuaf077.Peer-Reviewed Original ResearchCitationsConceptsReturn of spontaneous circulationIn-Hospital MortalityAssociated with in-hospital mortalityQTc prolongationCardiac arrestInterval prolongationShockable rhythmNeurological outcomeClinical outcomesAssociated with increased in-hospital mortalityAssociated with adverse clinical outcomesTpTe intervalT-peak to T-endSusceptibility to ventricular arrhythmiasQTc interval prolongationIn-hospital cardiac arrestAdverse clinical outcomesT-end (TpTeOut-of-hospitalT-endSpontaneous circulationVentricular arrhythmiasVentricular repolarizationQTcRepolarisation abnormalitiesStatus epilepticus in older adults: A critical review
Woodward M, Armahizer M, Wang T, Badjatia N, Johnson E, Gilmore E. Status epilepticus in older adults: A critical review. Epilepsia 2025, 66: 3118-3137. PMID: 40365943, PMCID: PMC12353664, DOI: 10.1111/epi.18453.Peer-Reviewed Original ResearchAltmetricConceptsEstablished Status Epilepticus Treatment TrialStatus epilepticusOlder adultsTreatment trialsMortality associated with SEIncidence of status epilepticusAssociated with poor outcomesSensitivity to benzodiazepinesMen aged >Analysis of older adultsPhysiologic changes of agingAdults aged <Incidence of SERandomized clinical trialsEfficacy of treatmentPost Hoc AnalysisHigh morbidityPoor outcomeAntiseizure medicationsEstablished treatmentTreatment selectionChanges of agingOlder trialsHigher incidenceIncidence increasesEarly Pupil Abnormality Frequency Predicts Poor Outcomes and Enhances International Mission for Prognosis and Analysis of Clinical Trials in Traumatic Brain Injury (IMPACT) Model Prognostication in Traumatic Brain Injury
Veerapaneni D, Sakthiyendran N, Du Y, Mallinger L, Reinert A, Kim S, Nguyen C, Daneshmand A, Abdalkader M, Mohammed S, Dupuis J, Sheth K, Gilmore E, Greer D, Ong C. Early Pupil Abnormality Frequency Predicts Poor Outcomes and Enhances International Mission for Prognosis and Analysis of Clinical Trials in Traumatic Brain Injury (IMPACT) Model Prognostication in Traumatic Brain Injury. Critical Care Explorations 2025, 7: e1257. PMID: 40299976, PMCID: PMC12043342, DOI: 10.1097/cce.0000000000001257.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsTraumatic brain injuryNeurological Pupil indexUnfavorable discharge dispositionPrimary diagnosis of traumatic brain injuryDischarge dispositionPupil abnormalitiesAcute care settingInternational Mission for PrognosisDiagnosis of traumatic brain injuryQuantitative pupillometryTraumatic brain injury severityBrain injuryMultivariate logistic regressionAnalysis of clinical trialsCare settingsAssociated with unfavorable discharge outcomesTraumatic brain injury prognostic modelsClinical trialsDischarge outcomesUnfavorable discharge outcomesPrognostic modelPupillary assessmentAssociated with unfavorable outcomesDynamic prognostic informationInclusion criteriaCorrection: Evolution of EEG Findings in Patients with Acute Brain Injury
Narrett J, Byrnes M, Gilmore E, Hirsch L, Punia V, Sivaraju A. Correction: Evolution of EEG Findings in Patients with Acute Brain Injury. Neurocritical Care 2025, 43: 361-361. PMID: 40229634, DOI: 10.1007/s12028-025-02266-5.Peer-Reviewed Original Research
Clinical Trials
Current Trials
Biomarker and Edema Attenuation in IntraCerebral Hemorrhage (BEACH)
HIC ID2000031665RoleSub InvestigatorPrimary Completion Date12/01/2025Recruiting ParticipantsGenderBothAge18+ yearsBrain Oxygen Optimization in Severe TBI, Phase 3 (BOOST3)
HIC ID2000024956RolePrincipal InvestigatorPrimary Completion Date07/01/2023Recruiting ParticipantsGenderBothAge14+ yearsAnticoagulation for Stroke Prevention and Recovery After ICH (ASPIRE)
HIC ID2000026409RoleSub InvestigatorPrimary Completion Date04/30/2028Recruiting ParticipantsGenderBothAge18+ yearsTransforming Acute Stroke Detection through Real Time Neurological Monitoring
HIC ID1605017863RoleSub InvestigatorPrimary Completion Date07/01/2017Recruiting ParticipantsGenderBothAge18+ yearsMultimodal Outcome CHAracterization (MOCHA) in comatose cardiac arrest patients
HIC ID1506016080REGRoleSub InvestigatorPrimary Completion Date12/31/2025Recruiting ParticipantsGenderBothAge18+ years
Academic Achievements & Community Involvement
Copy Link
Honors
honor Board Member
04/20/2022National AwardAmerican Board of Clinical NeurophysiologyDetailsUnited Stateshonor Fellow
10/31/2020National AwardNeurocritical Care SocietyDetailsUnited Stateshonor A.B. Baker Teacher Recognition Award
04/01/2020National AwardAmerican Academy of NeurologyDetailsUnited Stateshonor Fellow
02/01/2019National AwardAmerican Clinical Neurophysiology SocietyDetailsUnited States
Clinical Care
Copy Link
Overview
Emily Gilmore, MD, is a critical care neurologist at Yale Medicine with subspecialty training in critical care EEG (brain wave) monitoring. She has a particular interest in patients with traumatic brain injury, cardiac arrest and subarachnoid hemorrhage.
During medical school, Dr. Gilmore developed an interest in end-of-life and palliative care through her work with hospice and caring for children with devastating neurologic disorders. The combination of these experiences eventually led her to the field of critical care neurology, which drew upon all her interests. “I found the combination of helping to save a patient’s life using advanced technology and also the privilege of assisting families in that critical time of transition a really satisfying aspect of doing critical care neurology,” she says.
Dr. Gilmore helps her patients by reassuring them or their loved ones that her team is going to do everything they can to get them through a life changing event. “The patients and their families are the most rewarding and inspiring parts of my job,” says Dr. Gilmore. “Seeing peoples’ resilience and how their families support them through that and help us in the decision-making process is really powerful.”
In addition to seeing patients, Dr. Gilmore is an associate professor in the divisions of neuro-critical care and emergency neurology as well as epilepsy at the Yale School of Medicine. She is involved in studies assessing new treatments for refractory status epilepticus as well as biomarkers of epileptogenesis (the process in which the brain develops epilepsy) in severe traumatic brain injury. Dr Gilmore hopes her research on brain wave activity and how it is affected by neurologic injury will help improve functional and cognitive outcomes for survivors of acute brain injury.
Clinical Specialties
Fact Sheets
Brain Injury
Learn More on Yale Medicine
Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileNews
Copy Link
Get In Touch
Copy Link
Contacts
Locations
Patient Care Locations
Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.