Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsChirag Parikh, MD, PhD, FACP
Professor AdjunctAbout
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Professor Adjunct
Biography
Dr. Parikh is an Adjunct Professor of Medicine, section of Nephrology. Currently at Johns Hopkins University, Dr. Parikh continues his research projects and collaborations with F. Perry Wilson, MD, MSCE, the Interim Director of the Program of Applied Translational Research (PATR) and with other faculty and collaborators within PATR.
Dr. Parikh received his MD from Mumbai, India in 1996. His post-graduate training involves Residency in Internal Medicine at Nassau University and SUNY in Stony Brook, NY, and Fellowship in Nephrology and Hypertension at the University of Colorado Health Sciences Center in Denver, CO. He also completed a PhD in Clinical Investigation and Translational Research at University of Colorado Health Sciences Center, Denver, CO in 2003. He is board certified in both Internal Medicine and Nephrology. He has received several awards, including the National Junior Physician Investigator Award from the American Federation of Medical Research and the Outstanding Investigator Award from the Society of Clinical Investigation.
Dr. Parikh conducts an active patient-oriented research program investigating the translational and epidemiological aspects of acute kidney injury (AKI) and other kidney related disorders. His major research interest is developing novel biomarkers of AKI. He is the Principal Investigator of the NIH sponsored TRIBE-AKI consortium that is conducting large studies for validating novel kidney injury biomarkers in setting of cardiac surgery, kidney transplantation, diabetic kidney disease and hepatorenal syndrome. He has authored more than 250 peer-reviewed papers, 50 book chapters and reviews, and he has given more than 50 invited lectures at scientific meetings and academic institutions around the world.
Departments & Organizations
Education & Training
- PhD
- University of Colorado at Denver (2003)
- MD
- Seth G.S. Medical College (1996)
Research
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Overview
Medical Research Interests
Public Health Interests
ORCID
0000-0001-9051-7385
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Dennis G Moledina, MD, PhD, FASN
F. Perry Wilson, MD, MSCE
Jason Greenberg, MD, MHS
Sherry Mansour, MD, MS, DO
Lloyd G. Cantley, MD
Mark Perazella, MD
Acute Kidney Injury
Kidney Diseases
Renal Insufficiency
Publications
2026
WCN26-7054 Value of Implementing Quality Metrics in Outpatient Nephrology Care
Cervantes C, Philbrook H, Bitzel J, Srialluri N, Parikh C, Jaar B. WCN26-7054 Value of Implementing Quality Metrics in Outpatient Nephrology Care. Kidney International Reports 2026, 11: 104514. DOI: 10.1016/j.ekir.2026.104514.Peer-Reviewed Original ResearchAssociations between exposure to polycyclic aromatic hydrocarbons and biomarkers of acute kidney injury among chilean agricultural workers
Tore G, DeSantiago M, Stapleton H, Obeid W, Parikh C, Kuiper J, Valenzuela M, Ferreccio C, Fazen L, Dickerson A, Cortés S, Quirós-Alcalá L. Associations between exposure to polycyclic aromatic hydrocarbons and biomarkers of acute kidney injury among chilean agricultural workers. International Journal Of Hygiene And Environmental Health 2026, 274: 114791. PMID: 41880841, DOI: 10.1016/j.ijheh.2026.114791.Peer-Reviewed Original ResearchConceptsPolycyclic aromatic hydrocarbonsPolycyclic aromatic hydrocarbon exposureAromatic hydrocarbonsParent polycyclic aromatic hydrocarbonsExposure to polycyclic aromatic hydrocarbonsUrinary polycyclic aromatic hydrocarbonsParent PAH compoundsConcentration of anthraceneInterquartile range increasePAH compoundsAssociated with higher urinary concentrationsHydroxy-PAHsExposure concentrationsRange increaseHigher urinary concentrationsUrinary concentrationsKnowledge gapsHydrocarbonsAgricultural communitiesConcentrationExposureChrysenePhenanthreneBenzo[e]pyreneBenzo[a]pyreneLow Urine Uromodulin Levels are Associated With Interstitial Fibrosis and Tubular Atrophy in Native Kidney Biopsies
Parikh M, Philbrook H, Hu D, Bitzel J, Xue J, DSouza S, Rosenberg A, Moledina D, Coca S, Parikh C, Menez S, Project K. Low Urine Uromodulin Levels are Associated With Interstitial Fibrosis and Tubular Atrophy in Native Kidney Biopsies. Kidney International Reports 2026, 11: 106351. PMID: 41883681, PMCID: PMC13010425, DOI: 10.1016/j.ekir.2026.106351.Peer-Reviewed Original ResearchConcordance of Pre-Biopsy and Post-Biopsy Diagnosis in Hospitalized Patients with Acute Kidney Injury.
McGredy M, Hu D, Philbrook H, Corona-Villalobos C, Rosenberg A, Moledina D, Coca S, Parikh C, Menez S. Concordance of Pre-Biopsy and Post-Biopsy Diagnosis in Hospitalized Patients with Acute Kidney Injury. Kidney360 2026 PMID: 41671053, DOI: 10.34067/kid.0000001151.Peer-Reviewed Original ResearchAltmetricConceptsAcute interstitial nephritisAcute tubular injuryPre-biopsy clinical diagnosisFocal segmental glomerulosclerosisPercutaneous kidney biopsyKidney biopsyClinical diagnosisPre-biopsyPost-biopsyClinical diagnosis of acute interstitial nephritisDiagnosis of acute interstitial nephritisGlomerular diseaseAcute kidney injuryNon-invasive testsJohns Hopkins HospitalFinal diagnosisAbsolute contraindicationAdult patientsKidney injuryTubular injuryAlternative diagnosesHistological findingsBiopsyInterstitial nephritisDiabetic nephropathyReimagining kidney value-based care: leveraging data science for dynamic, clinician-level risk prediction
Baughman D, Nagy P, Parikh C. Reimagining kidney value-based care: leveraging data science for dynamic, clinician-level risk prediction. Current Opinion In Nephrology & Hypertension 2026, 35: 360-366. PMID: 41631380, DOI: 10.1097/mnh.0000000000001162.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsValue-based paymentValue-based payment policiesClinician-level interventionsDose-response relationshipElectronic health recordsValue-based payment structuresStandardized electronic health recordChronic kidney diseaseRisk predictionChronic kidney disease outcomesCare deliveryCKD careHealth recordsPreventive carePayment modelsPatient-level modelsClinical informaticsClaims dataRisk estimatesCareInterventionAnnual metricsCost conditionsAnnual benchmarksEvaluation frameworkChronic Psychological Stress in Mice Induces Kidney Inflammation.
Rastegar T, Patel S, Kapoor R, Matsuura R, Freiman J, Bullock B, Welling P, Pluznick J, Parikh C, Crews D, Noel S, Tamashiro K, Rabb H. Chronic Psychological Stress in Mice Induces Kidney Inflammation. Kidney360 2026 PMID: 41538290, DOI: 10.34067/kid.0000001111.Peer-Reviewed Original ResearchConceptsNeutrophil Gelatinase-Associated LipocalinKidney inflammationT cellsElevated levels of cystatin CCystatin CPercentage of CD4+ T cellsChronic stressCD4+ T cellsLevels of cystatin CRegulatory T cellsSustained systemic inflammationT helper 17Elevated levelsTNF-a levelsChronic kidney diseaseMale C57BL/6J miceSpectral flow cytometryChronic psychological stressSerum creatinineStressed miceSystemic inflammationCS miceImmunological changesImmune cellsC57BL/6J mice
2025
Kidney Biorepositories
Gewin L, Parikh C, Jain S, Hung A, Bajwa A, Okusa M, Kumar S, Mansour S. Kidney Biorepositories. Kidney360 2025, 7: 426-434. PMID: 41348489, PMCID: PMC12935355, DOI: 10.34067/kid.0000001085.Peer-Reviewed Original ResearchAssociations of Blood Mitochondrial DNA Quality and Quantity with Risk of Kidney Function Decline
Eswarappa M, Katz R, Arking D, Shi W, Newcomb C, Tranah G, Ix J, Parikh C, Cummings S, Waikar S, Parikh S, Sarnak M, Shlipak M, Jotwani V. Associations of Blood Mitochondrial DNA Quality and Quantity with Risk of Kidney Function Decline. Clinical Journal Of The American Society Of Nephrology 2025, 21: 242-250. PMID: 41269922, PMCID: PMC12889926, DOI: 10.2215/cjn.0000000893.Peer-Reviewed Original ResearchConceptsMeasurement of mitochondrial DNAMtDNA heteroplasmyMtDNA-CNCopy numberAge-associated accumulationConsequences of mtDNA mutationsHigher mtDNA-CNMitochondrial DNA heteroplasmyMitochondrial DNA copy numberAccumulation of somatic mutationsDNA copy numberRisk of kidney function declineMitochondrial DNAMtDNA mutationsHeteroplasmyKidney function declineDNA qualityMitochondrial healthSomatic mutationsAssociated with higher incidenceHighest risk of kidney function declineMutationsBuffy coat specimensLow riskHigh riskRisk for Scrotal Surgery After Laparoscopic Donor Nephrectomy : A Population-Based Cohort Study.
Garg A, McArthur E, Sontrop J, Boudville N, Connaughton D, Cuerden M, Feldman L, Lam N, Lentine K, Nguan C, Parikh C, Segev D, Sener A, Smith G, Wang C, Weir M, Yohanna S, Young A, Naylor K. Risk for Scrotal Surgery After Laparoscopic Donor Nephrectomy : A Population-Based Cohort Study. Annals Of Internal Medicine 2025, 179: 23-31. PMID: 41213151, DOI: 10.7326/annals-25-02257.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPotential long-term complicationsScrotal surgeryLaparoscopic nephrectomyAdministrative health care databasesCanadian InstitutesPopulation-based cohort studyLiving Kidney DonorsCanadian Institutes of Health ResearchHealth care databasesFluid collectionKidney donorsLaparoscopic donor nephrectomyInguinal hernia repairCare databaseCohort entryHealth researchRural residentsLong-term riskCohort studyGeneral populationPrimary outcomeDonor nephrectomyScrotal swellingSurgery ratesMedian timeAssessing Deceased-Donor Kidneys Through Posttransplant Survival Prediction Algorithms
Potluri V, Rubin J, Zee J, Ratcliffe S, Harhay M, Abt P, Vail E, Parikh C, Bloom R, Gasparini A, Crowther M, Goldberg D, Reese P. Assessing Deceased-Donor Kidneys Through Posttransplant Survival Prediction Algorithms. American Journal Of Kidney Diseases 2025, 87: 18-30. PMID: 41135690, DOI: 10.1053/j.ajkd.2025.07.016.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsAllograft survivalKidney Donor Risk IndexDeceased-donor kidneysGraft functionLongitudinal laboratory dataRecipient variablesClinical variablesPrimary outcomeHepatitis C virus statusAdult kidney recipientsLaboratory dataDelayed graft functionRetrospective cohort studyDonor risk indexTransplantation Network dataAllograft functionAllograft failureSerum creatinineKidney recipientsAbstractText Label="ConclusionsCohort studyDonor raceSecondary outcomesSurvival prediction modelDeceased-donor
Academic Achievements & Community Involvement
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Honors
honor Jeff Gray Memorial "Translating to Management in AKI"
03/09/2017National AwardAKI and CRRT 2017 22nd International ConferenceDetailsUnited Stateshonor Dr. MD Motashaw Oration and Award for Research Accomplishment
04/24/2013International AwardSeth G.S. Medical College and KEM HospitalDetailsIndia
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