Ashwani Kumar, PhD
Associate Research ScientistCards
About
Research
Publications
2026
APOL1-risk alleles modulate T-cell receptor signaling to promote allograft rejection
Pell J, Tanvir E, Sun Z, Chernova I, Reghuvaran A, Nagata S, Guerra M, Choi J, Al Chaar S, Mizuno H, Dong K, Tian X, Ishibe R, Franchin B, Cravedi P, Kumar A, Barsotti G, Shi H, De Kumar B, Smithson S, Song W, He J, Chong A, Pober J, Somlo S, Gibson I, Popik W, Zhang Z, Craft J, Azzi J, Murakami N, Ishibe S, Heeger P, Menon M. APOL1-risk alleles modulate T-cell receptor signaling to promote allograft rejection. Journal Of Clinical Investigation 2026 PMID: 42262888, DOI: 10.1172/jci193173.Peer-Reviewed Original ResearchConcurrent Manifestation of Crescentic Anti-glomerular Basement Membrane Nephritis and Membranous Nephropathy
Vellaisamy G, Kumar A, Singh J, Nada R. Concurrent Manifestation of Crescentic Anti-glomerular Basement Membrane Nephritis and Membranous Nephropathy. Indian Journal Of Kidney Diseases 2026, 5: 123-126. DOI: 10.4103/ijkd.ijkd_6_26.Peer-Reviewed Original Research
2025
Design of precision therapeutics for a CKD risk allele by targeting Shroom3-Rock interaction
Reghuvaran A, Kumar A, Lin Q, Rajeevan N, Banu K, Sun Z, Shi H, Barsotti G, Tanvir E, Pell J, Perincheri S, Wei C, Bharathan B, Planoutene M, Eichmann A, Mas V, Zhang W, Cantley L, Xu L, Das B, He J, Menon M. Design of precision therapeutics for a CKD risk allele by targeting Shroom3-Rock interaction. Nature Communications 2025, 17: 1086. PMID: 41469391, PMCID: PMC12852734, DOI: 10.1038/s41467-025-67854-7.Peer-Reviewed Original ResearchDesign and development of a urinary cell pellet mRNA PCR-based assay for progressive kidney disease: Nephro-Dx.
Kumar A, Barsotti G, Yi Z, Sun Z, Reghuvaran A, Tanvir EM, Pell J, Shi H, Perincheri S, Shaw M, Kent C, Javed D, Leite P, Jayaram D, Turner J, Meliambro K, Luciano R, He JC, Moledina D, Wilson P, Zhang W, Menon MC. Design and development of a urinary cell pellet mRNA PCR-based assay for progressive kidney disease: Nephro-Dx. MedRxiv 2025 PMID: 41282816, DOI: 10.1101/2025.10.31.25338655.Peer-Reviewed Original ResearchImmunotactoid Glomerulonephritis Unmasked From C3 Glomerulopathy: A Diagnostic Dilemma in Spectrum of MGRS
Vellaisamy G, Lad D, Ramachandran R, Kumar A, Nada R. Immunotactoid Glomerulonephritis Unmasked From C3 Glomerulopathy: A Diagnostic Dilemma in Spectrum of MGRS. Indian Journal Of Kidney Diseases 2025, 4: 149-151. DOI: 10.4103/ijkd.ijkd_29_25.Peer-Reviewed Original ResearchVincristine in FSGS: Rediscovering an Old Therapeutic for FSGS
Kumar A, Prasad P, Menon M. Vincristine in FSGS: Rediscovering an Old Therapeutic for FSGS. Kidney International Reports 2025, 10: 3727-3729. PMID: 41278331, PMCID: PMC12640027, DOI: 10.1016/j.ekir.2025.09.018.Commentaries, Editorials and LettersA T-cell intrinsic Role for APOL1 Risk Alleles in Allograft Rejection.
Pell J, Tanvir EM, Sun Z, Chernova I, Reghuvaran A, Nagata S, Guerra M, Choi J, Chaar SA, Mizuno H, Dong K, Tian X, Ishibe R, Franchin B, Cravedi P, Kumar A, Barsotti G, Shi H, Kumar B, Song W, He C, Pober JS, Somlo S, Gibson IW, Popik W, Zhang Z, Craft J, Azzi J, Murakami N, Ishibe S, Heeger P, Menon MC. A T-cell intrinsic Role for APOL1 Risk Alleles in Allograft Rejection. BioRxiv 2025 PMID: 40791557, DOI: 10.1101/2025.07.14.664793.Peer-Reviewed Original ResearchAuthor Correction: LILRB3 genetic variation is associated with kidney transplant failure in African American recipients
Sun Z, Yi Z, Wei C, Wang W, Ren T, Cravedi P, Tedla F, Ward S, Azeloglu E, Schrider D, Li Y, Khan A, Zanoni F, Fu J, Ali S, Liu S, Liang D, Liu T, Li H, Xi C, Vy T, Mosoyan G, Sun Q, Kumar A, Zhang Z, Farouk S, Campell K, Ochando J, Lee K, Coca S, Xiang J, Connolly P, Gallon L, O’Connell P, Colvin R, Menon M, Nadkarni G, He J, Kraft M, Jiang X, Zhang X, Kiryluk K, Cherukuri A, Lakkis F, Zhang W, Chen S, Heeger P, Zhang W. Author Correction: LILRB3 genetic variation is associated with kidney transplant failure in African American recipients. Nature Medicine 2025, 31: 1712-1712. PMID: 40234733, DOI: 10.1038/s41591-025-03706-7.Commentaries, Editorials and LettersLILRB3 genetic variation is associated with kidney transplant failure in African American recipients
Sun Z, Yi Z, Wei C, Wang W, Ren T, Cravedi P, Tedla F, Ward S, Azeloglu E, Schrider D, Li Y, Khan A, Zanoni F, Fu J, Ali S, Liu S, Liang D, Liu T, Li H, Xi C, Vy T, Mosoyan G, Sun Q, Kumar A, Zhang Z, Farouk S, Campell K, Ochando J, Lee K, Coca S, Xiang J, Connolly P, Gallon L, O’Connell P, Colvin R, Menon M, Nadkarni G, He J, Kraft M, Jiang X, Zhang X, Kiryluk K, Cherukuri A, Lakkis F, Zhang W, Chen S, Heeger P, Zhang W. LILRB3 genetic variation is associated with kidney transplant failure in African American recipients. Nature Medicine 2025, 31: 1677-1687. PMID: 40065170, PMCID: PMC12527113, DOI: 10.1038/s41591-025-03568-z.Peer-Reviewed Original Research
2024
Clinical Characteristics and Outcomes of Neural Epidermal Growth Factor-like 1 Protein-Associated Membranous Nephropathy
Narayanasami S, Vijayakumar N, Trivedi M, Sekar A, Sulaiman S, Nayak S, Inamdar N, Sharma S, Parthasarathy R, Kadam V, Keskar V, Bagai S, Kumar A, Reen B, Kurien A, Sharma A, Khullar D, Hafeeq B, Krishnakumar A, Rahman Kv S, Na I, Nair S, Divyaveer S, Rathi M, Kohli H, Nada R, Ramachandran R. Clinical Characteristics and Outcomes of Neural Epidermal Growth Factor-like 1 Protein-Associated Membranous Nephropathy. Kidney International Reports 2024, 9: 1513-1516. PMID: 38707806, PMCID: PMC11068952, DOI: 10.1016/j.ekir.2024.02.1405.Peer-Reviewed Original Research
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Yale School of Medicine
Internal Medicine-Nephrology, The Anlyan Center, 1 Gilbert Street
New Haven, Connecticut 06519
United States