2009
Regulation of Endothelial Nitric Oxide Synthase (eNOS) in Myocardium Subjected to Cardioplegic Arrest
Fischer U, Klass O, Cox C, Stock U, Antonyan A, Brixius K, Fischer J, Mehlhorn U, Bloch W. Regulation of Endothelial Nitric Oxide Synthase (eNOS) in Myocardium Subjected to Cardioplegic Arrest. The Thoracic And Cardiovascular Surgeon 2009, 57: 379-385. PMID: 19795322, DOI: 10.1055/s-0029-1185873.Peer-Reviewed Original ResearchAnimalsCardiopulmonary BypassEnzyme ActivationFemaleHeart Arrest, InducedHeart VentriclesImmunohistochemistryMaleMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3Models, AnimalMyocardial ContractionMyocardiumNitric Oxide Synthase Type IIIPhosphorylationProto-Oncogene Proteins c-aktSerineSwineThreonineTime FactorsVentricular Function, Left
2004
Effect of the Na+/H+ exchange inhibitor eniporide on cardiac performance and myocardial high energy phosphates in pigs subjected to cardioplegic arrest
Klass O, Fischer U, Perez E, Easo J, Bosse M, Fischer J, Tossios P, Mehlhorn U. Effect of the Na+/H+ exchange inhibitor eniporide on cardiac performance and myocardial high energy phosphates in pigs subjected to cardioplegic arrest. The Annals Of Thoracic Surgery 2004, 77: 658-663. PMID: 14759455, DOI: 10.1016/s0003-4975(03)01604-7.Peer-Reviewed Original ResearchMeSH KeywordsAdenine NucleotidesAnimalsCardiopulmonary BypassDose-Response Relationship, DrugEnergy MetabolismGlycogenGuanidinesHeart Arrest, InducedHemodynamicsMyocardial ContractionMyocardial Reperfusion InjuryPremedicationSodium-Hydrogen ExchangersSulfonesSwineVentricular Function, LeftWater-Electrolyte BalanceConceptsIschemia/reperfusionCardiopulmonary bypassCardioplegic arrestCrystalloid cardioplegic arrestCardiac performanceMyocardial adenine nucleotidesPreload recruitable stroke workMyocardial ischemia/reperfusionLeft ventricular isovolumic relaxationCold crystalloid cardioplegic arrestRecruitable stroke workMyocardial high-energy phosphatesHigh-energy phosphate contentHealthy pig heartsVentricular isovolumic relaxationAdenine nucleotidesRelevant pig modelHigh-energy phosphatesCardiac indexStandard hemodynamicsAcute studySystemic infusionStroke workVascular pressuresIsovolumic relaxation