2010
A Novel Physiologic Model for the Study of Abdominal Compartment Syndrome (ACS)
Shah S, Jimenez F, Walker P, Xue H, Uray K, Aroom K, Fischer U, Laine G, Stewart R, Norbury K, Cox C. A Novel Physiologic Model for the Study of Abdominal Compartment Syndrome (ACS). Journal Of Trauma And Acute Care Surgery 2010, 68: 682-689. PMID: 20220423, DOI: 10.1097/ta.0b013e3181c453cb.Peer-Reviewed Original ResearchConceptsAbdominal compartment syndromeMean arterial pressureHemorrhagic shock/resuscitationShock/resuscitationUrine outputInspiratory pressureAbdominal pressureDevelopment of ACSMesenteric venous hypertensionPulmonary artery pressureCentral venous pressureDamage control surgeryPeak inspiratory pressureLarge animal modelArtery pressureVenous hypertensionArterial pressureCompartment syndromeVenous pressureControl surgeryHemodynamic measurementsHemorrhagic shockAbdominal packingIntraperitoneal instillationBase excess
2005
Resuscitation-Induced Gut Edema and Intestinal Dysfunction
Moore-Olufemi S, Xue H, Attuwaybi B, Fischer U, Harari Y, Oliver D, Weisbrodt N, Allen S, Moore F, Stewart R, Laine G, Cox C. Resuscitation-Induced Gut Edema and Intestinal Dysfunction. Journal Of Trauma And Acute Care Surgery 2005, 58: 264-270. PMID: 15706186, DOI: 10.1097/01.ta.0000133571.64393.d2.Peer-Reviewed Original ResearchConceptsMesenteric venous hypertensionGut edemaIntra-abdominal hypertensionVenous hypertensionIntestinal transitGroup BAltered gut barrier functionIschemia/reperfusion injuryBarrier functionGut barrier functionML/Mucosal injuryMyeloperoxidase activityFluid resuscitationIntestinal dysfunctionMucosal permeabilityReperfusion injurySham surgeryGut motilityGut functionHypertensionGroup AEdemaTissue resistanceInjury measurements