2022
Eligibility of Patients with Chronic Limb Threatening Ischemia for Deep Venous Arterialization
Satam K, Aboian E, Huttler J, Zhuo H, Zhang Y, Tonnessen B, Cardella J, Guzman RJ, Ochoa Chaar CI. Eligibility of Patients with Chronic Limb Threatening Ischemia for Deep Venous Arterialization. Annals Of Vascular Surgery 2022, 86: 260-267. PMID: 35589034, DOI: 10.1016/j.avsg.2022.04.051.Peer-Reviewed Original ResearchConceptsPercutaneous deep venous arterializationChronic limb threatening ischemiaPeripheral arterial diseaseGlobal Limb Anatomic Staging SystemPatent tibial arteriesDeep venous arterializationLimb threatening ischemiaMajor amputationTibial arteryProximal diseaseLimb salvageVenous arterializationExtensive peripheral arterial diseaseAdvanced limb ischemiaAnatomic staging systemEligibility of patientsLower extremity angiogramsProportion of patientsCongestive heart failureNew therapeutic modalitiesElectronic medical recordsLimb ischemiaConsecutive patientsEndovascular therapyHeart failure
2020
Lower Extremity Revascularization for Chronic Limb-Threatening Ischemia among Patients at the Extremes of Age
Kim TI, Aboian E, Fischer U, Zhang Y, Guzman RJ, Ochoa Chaar CI. Lower Extremity Revascularization for Chronic Limb-Threatening Ischemia among Patients at the Extremes of Age. Annals Of Vascular Surgery 2020, 72: 517-528. PMID: 32927042, DOI: 10.1016/j.avsg.2020.08.135.Peer-Reviewed Original ResearchMeSH KeywordsAge of OnsetAgedAged, 80 and overAgingAmputation, SurgicalChronic DiseaseDatabases, FactualEndovascular ProceduresFemaleHumansIschemiaLimb SalvageLower ExtremityMaleMiddle AgedPeripheral Arterial DiseaseRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeVascular Surgical ProceduresConceptsChronic limb-threatening ischemiaLower extremity revascularizationExtremes of ageRisk factor profileMajor amputationPatients 51Extremity revascularizationFactor profileDistinct risk factor profilesAge groupsChronic limb threatening ischemiaLimb threatening ischemiaLimb-threatening ischemiaMajor amputation ratePeripheral artery diseaseGroup of patientsInsulin-dependent diabetesExtreme age groupsSuprainguinal bypassAmputation rateElderly patientsInfrainguinal bypassActive smokersArtery diseaseMultivariable analysis
2019
Cell therapy of critical limb ischemia-problems and prospects.
Osipova O, Saaya S, Karpenko A, Zakian S, Aboian E. Cell therapy of critical limb ischemia-problems and prospects. Vasa 2019, 48: 461-471. PMID: 30969159, DOI: 10.1024/0301-1526/a000787.Peer-Reviewed Original ResearchMeSH KeywordsAmputation, SurgicalCell- and Tissue-Based TherapyCritical IllnessGenetic TherapyHumansIschemiaLimb SalvageTreatment OutcomeVascular Surgical ProceduresConceptsCritical limb ischemiaCell therapyStem cellsHuman trial dataGene therapyIndirect revascularizationSurgical revascularizationLimb ischemiaCLI treatmentCritical limbClinical trialsParacrine effectsFuture stem cellTherapyTrial dataAngiogenesis gene therapyVasculogenic propertiesProgenitor cellsPutative mechanismsRevascularizationCellsIschemiaPatientsActive substances