1987
Treatment with verapamil and adenosine triphosphate-MgCl2 reduces cyclosporine nephrotoxicity.
Sumpio B, Baue A, Chaudry I. Treatment with verapamil and adenosine triphosphate-MgCl2 reduces cyclosporine nephrotoxicity. Surgery 1987, 101: 315-22. PMID: 2950608.Peer-Reviewed Original ResearchConceptsGlomerular filtration rateRenal perfusate flowTubular absorptionPerfusate flowUrine outputImmunosuppressive agentsVerapamil pretreatmentClearance periodMicrograms/ATP-MgCl2 treatmentControl clearance periodsUse of cyclosporineCombination of verapamilSerious side effectsTissue ATP levelsEffects of adenosineCyA treatmentCyA nephrotoxicityCyclosporine nephrotoxicityVerapamil treatmentTubular functionRenal flowNephrotoxic potentialFiltration rateATP-MgCl2
1985
Results of Aortic Grafting in Occlusive vs Aneurysmal Disease
Sumpio B, Traquina D, Gusberg R. Results of Aortic Grafting in Occlusive vs Aneurysmal Disease. JAMA Surgery 1985, 120: 817-819. PMID: 4015373, DOI: 10.1001/archsurg.1985.01390310055012.Peer-Reviewed Original ResearchConceptsOcclusive diseaseAortic aneurysmAortic graftingOCC patientsSignificant intraoperative differenceSubsequent postoperative morbidityAtherosclerotic occlusive diseasePopulation of patientsDifferent patient groupsSignificant differencesRAA patientsAortic surgeryGraft surgeryPostoperative morbidityClamp timeSmoking historyDiabetes mellitusIntraoperative differencesPulmonary diseaseUrine outputFluid administrationAneurysmal diseaseAsymptomatic aneurysmsPatient groupRetrospective study