1988
Variceal Bleeding, Hypersplenism, and Systemic Mastocytosis: Pathophysiology and Management
Sumpio BE, O'Leary G, Gusberg RJ. Variceal Bleeding, Hypersplenism, and Systemic Mastocytosis: Pathophysiology and Management. JAMA Surgery 1988, 123: 767-769. PMID: 3130825, DOI: 10.1001/archsurg.1988.01400300113020.Peer-Reviewed Original ResearchConceptsSystemic mastocytosisType of shuntTissue mast cellsPortal pressure measurementsIntrahepatic fibrosisSatisfactory blockadePortal hypertensionVariceal bleedingPortal pressureShunt surgerySplenic bloodHistamine releaseSurgical diseaseHemodynamic issuesHistamine antagonistsMast cellsDisodium cromoglycateSystemic circulationSystemic effectsAbnormal proliferationMastocytosisUltrastructural studyPressure measurementsHypersplenismHypertension
1984
Accelerated functional recovery of isolated rat kidney with ATP-MgCl2 after warm ischemia
Sumpio BE, Chaudry IH, Clemens MG, Baue AE. Accelerated functional recovery of isolated rat kidney with ATP-MgCl2 after warm ischemia. American Journal Of Physiology 1984, 247: r1047-r1053. PMID: 6334446, DOI: 10.1152/ajpregu.1984.247.6.r1047.Peer-Reviewed Original ResearchConceptsRenal perfusate flow rateMM ATP-MgCl2Min of perfusionIsolated rat kidneyATP-MgCl2Renal functionWarm ischemiaWhole kidney inulin clearanceRat kidneyAccelerated functional recoveryMin of reperfusionMin of ischemiaUrine flow rateTissue ATP levelsFractional absorptionFunctional recoveryNormothermic ischemiaIschemia resultsMin ischemiaPerfusate flow rateInulin clearanceEarly recoverySystemic effectsIschemiaSodium values