Kinetics, competition, and selectivity of tubular absorption of proteins
Sumpio BE, Maack T. Kinetics, competition, and selectivity of tubular absorption of proteins. American Journal Of Physiology 1982, 243: f379-f392. PMID: 7124951, DOI: 10.1152/ajprenal.1982.243.4.f379.Peer-Reviewed Original ResearchConceptsBeta 2MTubular absorptionHuman growth hormoneLow perfusate calcium concentrationsPerfusate calcium concentrationMorphologic damageTubular epitheliumProximal tubulesGrowth hormoneRat kidneyCationic proteinCalcium concentrationSaturable processSaturating loadSelective effectLuminal wallLow apparent affinityTubulesImportant determinantReversible mannerApparent affinityMicrovilliProteinKidney