Phospholipase C: A Putative Mechanotransducer for Endothelial Cell Response to Acute Hemodynamic Changes
Brophy CM, Mills I, Rosales O, Isales C, Sumpio BE. Phospholipase C: A Putative Mechanotransducer for Endothelial Cell Response to Acute Hemodynamic Changes. Biochemical And Biophysical Research Communications 1993, 190: 576-581. PMID: 8427600, DOI: 10.1006/bbrc.1993.1087.Peer-Reviewed Original ResearchConceptsEndothelial cellsAcute hemodynamic changesPhospholipase C activationHemodynamic changesProduction of inositolAcute decreaseAcute increaseIP3 generationEndothelial cell responsesCell responsesIP3 productionPutative mechanotransducersTransient increaseSpecific signal transduction pathwaysOngoing studiesCardiac cycleC activationSignal transduction pathwaysTransduction pathways