2010
Prostaglandin receptors EP2 and IP are detectable in atherosclerotic arteries and plaques.
Muto A, Nishibe T, Miyauchi Y, Kondo Y, Yamamoto Y, Dardik A, Shigematsu H. Prostaglandin receptors EP2 and IP are detectable in atherosclerotic arteries and plaques. International Angiology 2010, 29: 43-8. PMID: 20357748.Peer-Reviewed Original ResearchConceptsArteriosclerosis obliteransAtherosclerotic femoral arteriesPharmacological treatmentFemoral arteryReceptor EP2IP receptorAtherosclerotic plaquesMedial layerAtherosclerotic arteriesWestern blottingSevere arteriosclerosis obliteransFemoropopliteal bypass surgeryCOX-2 expressionProstaglandin receptor agonistsProstaglandin receptor EP2Pharmacological managementBypass surgeryReceptor agonistArterial intimaIntimal layerPG receptorsArteryPlatelet aggregationPatientsEP2
2006
Presence of prostacyclin receptor in arteriosclerotic human femoral artery.
Muto A, Kondo Y, Yamamoto Y, Yamada H, Washimi O, Miyauchi Y, Kudo F, Dardik A, Nishibe T. Presence of prostacyclin receptor in arteriosclerotic human femoral artery. International Angiology 2006, 25: 175-8. PMID: 16763535.Peer-Reviewed Case Reports and Technical NotesMeSH KeywordsAged, 80 and overAtherosclerosisBiomarkersFemaleFemoral ArteryHumansImmunohistochemistryReceptors, EpoprostenolSeverity of Illness IndexConceptsFemoral arteryVascular endothelial cellsEndothelial cellsArteriosclerosis obliteransHuman femoral arteriesProstacyclin analogueIP receptorProstacyclin receptorLuminal sideVon Willebrand factorIschemic symptomsVascular eventsRelaxant effectLower extremitiesCardiovascular homeostasisLimb amputationAtherosclerotic lesionsPositive cellsArterySingle immunohistochemistryWillebrand factorReceptorsStrong expressionObliteransPatients