2023
2023 Vascular Research Initiatives Conference: Structural and Immune Cells in Vascular Disease
Thaxton C, Gallagher K, Dardik A. 2023 Vascular Research Initiatives Conference: Structural and Immune Cells in Vascular Disease. JVS Vascular Science 2023, 4: 100117. PMID: 37649474, PMCID: PMC10463243, DOI: 10.1016/j.jvssci.2023.100117.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsVascular diseaseImmune cellsNovel immunotherapeutic targetAtherosclerotic cardiovascular diseaseAmerican Heart AssociationBasic science researchersImmune checkpointsVenous diseaseImmunotherapeutic targetHeart AssociationCardiovascular diseaseVascular conditionsImmune systemDiseaseVascular regenerationVascular cliniciansFirst dayNational InstituteAtherosclerosisTranslational scienceStem cellsResident researchCellsTranslational fieldAortopathy
2021
Stem cell therapy in vascular diseases
Navarro T, Lopes L, Dardik A. Stem cell therapy in vascular diseases. Revista Ciências Em Saúde 2021, 11: 1-2. DOI: 10.21876/rcshci.v11i4.1247.Commentaries, Editorials and LettersChapter 12 Induced pluripotent stem cells in wound healing
Gao X, Gorecka J, Cheema U, Gu Y, Wu Y, Dardik A. Chapter 12 Induced pluripotent stem cells in wound healing. 2021, 269-290. DOI: 10.1016/b978-0-12-822229-4.00003-6.ChaptersPluripotent stem cellsCell-free extracellular vesiclesIdeal delivery platformSomatic donor cellsStem cellsDestruction of embryosPluripotent stem cell populationDelivery platformDelivery scaffoldsRegenerative medicineIPSC technologyWidespread clinical adoptionTissue regenerationStem cell sourceTremendous advantagesCell sourceCell therapyPromising approachExciting new strategyIPSCsStem cell populationNew strategyExtracellular vesiclesUndifferentiated cellsTranslational potential
2020
Stem Cell Delivery Techniques for Stroke and Peripheral Artery Disease
Lee S, Fereydooni A, Dardik A. Stem Cell Delivery Techniques for Stroke and Peripheral Artery Disease. 2020, 69-103. DOI: 10.1007/978-3-030-56954-9_3.ChaptersPeripheral artery diseaseArtery diseaseImpact of patientStem cellsVascular diseaseTherapeutic effectHuman trialsOptimal doseTarget organsPharmaceutic agentsCell therapyDiseaseCell delivery techniquesStrokeCell factorPatientsTherapyDelivery techniquesDiverse populationsDelivery methodsCellsDelivery optionsDoseTrialsStem Cell Therapy for Thromboangiitis Obliterans (Buerger’s Disease)
Dash B, Peyvandi H, Duan K, Richardson E, Ndon S, Gabrick K, Faz A, Persing J, Dardik A, Hsia H. Stem Cell Therapy for Thromboangiitis Obliterans (Buerger’s Disease). Processes 2020, 8: 1408. DOI: 10.3390/pr8111408.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsThromboangiitis obliteransYoung male smokersBuerger's diseaseImmunomodulatory approachesMale smokersSurgical bypassPathological findingsTreatment modalitiesVascular diseaseDefinitive cureLower extremitiesMedium arteriesLesion treatmentTherapeutic modalitiesTAO treatmentTherapeutic angiogenesisCell therapyDiseaseObliteransStem cellsCurrent knowledgeModalitiesTreatmentPotential optionVasculitisInduced pluripotent stem cell-derived smooth muscle cells increase angiogenesis and accelerate diabetic wound healing
Gorecka J, Gao X, Fereydooni A, Dash BC, Luo J, Lee SR, Taniguchi R, Hsia HC, Qyang Y, Dardik A. Induced pluripotent stem cell-derived smooth muscle cells increase angiogenesis and accelerate diabetic wound healing. Regenerative Medicine 2020, 15: 1277-1293. PMID: 32228292, PMCID: PMC7304438, DOI: 10.2217/rme-2019-0086.Peer-Reviewed Original ResearchConceptsSmooth muscle cellsMuscle cellsDiabetic wound healingWound healingPro-angiogenic cytokinesMurine AdiposeStem cellsType macrophagesCollagen scaffoldsCultured mediumM2-type macrophagesCellsNumber of totalNew candidatesAngiogenesisNude miceDiabetic woundsPromising new candidateScaffoldsHealingCytokinesExpressionSecreteWoundsAdipose