2021
High expression of cell adhesion molecule 2 unfavorably impacts survival in non-small cell lung cancer patients with brain metastases
Dai L, Li YH, Liang YY, Zhao J, Chen G, Yin J, Postmus PE, Addeo A, Blasberg JD, Onesti CE, Liao ZW, Rao XG, Long HD. High expression of cell adhesion molecule 2 unfavorably impacts survival in non-small cell lung cancer patients with brain metastases. Journal Of Thoracic Disease 2021, 13: 2437-2446. PMID: 34012591, PMCID: PMC8107517, DOI: 10.21037/jtd-21-307.Peer-Reviewed Original ResearchNon-small cell lung cancer patientsCell lung cancer patientsBrain metastasesKaplan-Meier analysisNSCLC patientsLung cancer patientsCell adhesion molecule 2Overall survivalCox analysisPoor prognosisCancer patientsAffiliated Cancer HospitalHigh expressionIndependent risk factorSolid organ malignanciesOS of patientsCADM2 expressionLymph node metastasisTumor T stagePotential prognostic significanceGuangzhou Medical UniversityExpression levelsReal-time polymerase chain reactionQuantitative real-time polymerase chain reactionChi-square test
2020
Invasive Staging Procedures Do Not Prevent Nodal Metastases From Being Missed in Stage I Lung Cancer
Resio BJ, Canavan M, Mase V, Dhanasopon AP, Blasberg JD, Boffa DJ. Invasive Staging Procedures Do Not Prevent Nodal Metastases From Being Missed in Stage I Lung Cancer. The Annals Of Thoracic Surgery 2020, 110: 390-397. PMID: 32283084, DOI: 10.1016/j.athoracsur.2020.03.026.Peer-Reviewed Original ResearchConceptsStage I lung cancerI lung cancerMissed nodal metastasisClinical stage I lung cancerNodal metastasisLung cancerPositron emission tomographyStaging evaluationCancer patientsEndobronchial ultrasoundInvasive nodalClinical stage I patientsEarly-stage lung cancer patientsOccult lymph node metastasisEmission tomographyThoracic Surgeons General Thoracic Surgery DatabaseInvasive staging proceduresClinical stage IStage I patientsTreatment-naive patientsGeneral Thoracic Surgery DatabaseLow-risk cohortOccult nodal metastasisLymph node metastasisLung cancer patients
2019
Quantitative FDG PET/CT may help risk-stratify early-stage non-small cell lung cancer patients at risk for recurrence following anatomic resection
Harmon S, Seder CW, Chen S, Traynor A, Jeraj R, Blasberg JD. Quantitative FDG PET/CT may help risk-stratify early-stage non-small cell lung cancer patients at risk for recurrence following anatomic resection. Journal Of Thoracic Disease 2019, 11: 1106-1116. PMID: 31179052, PMCID: PMC6531752, DOI: 10.21037/jtd.2019.04.46.Peer-Reviewed Original ResearchDisease-free survivalSquamous cell carcinomaNon-small cell lung cancer patientsStandardized uptake valueCell lung cancer patientsEarly-stage NSCLCLung cancer patientsDisease recurrenceAnatomic resectionOverall survivalCancer patientsF-fluorodeoxyglucose positron emission tomography/computerized tomographyEarly stage non-small cell lung cancer patientsStage I/II NSCLC patientsPositron emission tomography/computerized tomographyCox proportional hazards regressionFDG PET/CTTomography/computerized tomographyQuantitative FDG-PET/CTPathologic node statusYears of resectionPreoperative risk factorsHigh-risk patientsSignificant univariate predictorsPrimary tumor volume
2018
Variable impact of prior cancer history on the survival of lung cancer patients
Monsalve AF, Hoag JR, Resio BJ, Chiu AS, Brown LB, Detterbeck FC, Blasberg JD, Boffa DJ. Variable impact of prior cancer history on the survival of lung cancer patients. Lung Cancer 2018, 127: 130-137. PMID: 30642541, DOI: 10.1016/j.lungcan.2018.11.040.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerPrior cancer historyNational Cancer DatabaseCancer historyOverall survivalNSCLC patientsMultivariable Cox proportional hazards regression modelsTreatment approachesCox proportional hazards regression modelProportional hazards regression modelsKaplan-Meier survival curvesNSCLC patient survivalCell lung cancerHazards regression modelsLung cancer patientsPrior cancerPrior malignancyNSCLC survivalPatient survivalCancer patientsLung cancerCancer DatabasePatient's potentialPrior historyPatientsProgress in the Management of Early-Stage Non–Small Cell Lung Cancer in 2017
Donington JS, Kim YT, Tong B, Moreira AL, Bessich J, Weiss KD, Colson YL, Wigle D, Osarogiagbon RU, Zweig J, Wakelee H, Blasberg J, Daly M, Backhus L, Van Schil P. Progress in the Management of Early-Stage Non–Small Cell Lung Cancer in 2017. Journal Of Thoracic Oncology 2018, 13: 767-778. PMID: 29654928, DOI: 10.1016/j.jtho.2018.04.002.Peer-Reviewed Original ResearchConceptsCell lung cancerLung cancerEarly-stage non-small cell lung cancerNon-small cell lung cancerEarly-stage lung cancer patientsSmall cell lung cancerEarly-Stage NonEarly-stage diseaseLung cancer patientsQuality of lifeAdvanced diseaseAdjuvant therapyCancer patientsThoracic oncologyFocused updateSurgical techniqueTailor treatmentCancerDiseaseLandscape of careCareMultiple areasAnnual updateUnpublished dataNovel unpublished data
2017
Fate of Pneumonectomy Patients Variably Captured by Non-Small Cell Lung Cancer Staging System
Dhanasopon AP, Salazar MC, Hoag JR, Rosen JE, Kim AW, Detterbeck FC, Blasberg JD, Boffa DJ. Fate of Pneumonectomy Patients Variably Captured by Non-Small Cell Lung Cancer Staging System. The Annals Of Thoracic Surgery 2017, 104: 1829-1836. PMID: 29074151, DOI: 10.1016/j.athoracsur.2017.06.073.Peer-Reviewed Original ResearchConceptsLung cancer staging systemCancer (AJCC) staging systemPneumonectomy patientsLung cancerMortality riskStage IStaging systemLobectomy patientsCox modelNon-small cell lung cancerMultivariable Cox modelNational Cancer DatabaseTreatment-naive patientsOverall survival curvesCell lung cancerLung cancer patientsBenefits of treatmentHigher mortality riskStage-specific survivalRight pneumonectomyLeft pneumonectomyCancer patientsCancer DatabaseInclusion criteriaPneumonectomy