2020
Risk of peri-operative complications in children receiving preoperative steroids
Mets EJ, Chouairi F, Mirza H, Allam O, Park KE, Junn A, Alperovich M. Risk of peri-operative complications in children receiving preoperative steroids. Pediatric Surgery International 2020, 36: 1345-1352. PMID: 32918623, DOI: 10.1007/s00383-020-04742-9.Peer-Reviewed Original ResearchConceptsAdverse eventsPediatric patientsSteroid usePreoperative steroidsNational Surgical Quality Improvement Project Pediatric databaseThirty-day adverse eventsPropensity scorePostoperative adverse eventsPeri-operative complicationsPediatric surgery patientsSimilar larger studiesMore comorbiditiesPerioperative impactHospital stayPerioperative complicationsAdult patientsPatient demographicsSteroid treatmentSurgery patientsSurgical variablesWound dehiscenceSurgical outcomesPediatric databasePatientsLarger studyWhat Is the Difference in Cranial Base Morphology in Isolated and Syndromic Bicoronal Synostosis?
Lu X, Forte AJ, Wilson AT, Park KE, Allam O, Mozaffari MA, Alperovich M, Steinbacher DM, Alonso N, Persing JA. What Is the Difference in Cranial Base Morphology in Isolated and Syndromic Bicoronal Synostosis? Plastic & Reconstructive Surgery 2020, 146: 599-610. PMID: 32842109, DOI: 10.1097/prs.0000000000007068.Peer-Reviewed Original ResearchComparison of Neurocognitive Outcomes in Postoperative Adolescents with Unilateral Coronal Synostosis.
Wu RT, Gabrick KS, Singh A, Landi N, Taylor JA, Bartlett SP, Persing JA, Alperovich M. Comparison of Neurocognitive Outcomes in Postoperative Adolescents with Unilateral Coronal Synostosis. Plastic & Reconstructive Surgery 2020, 146: 614-619. PMID: 32842112, DOI: 10.1097/prs.0000000000007067.Peer-Reviewed Original ResearchConceptsPerformance intelligence quotientVisual-motor integrationVerbal intelligence quotientIntelligence quotientMean full-scale intelligence quotientMotor integrationLeft-sided patientsRight-side patientsNonsyndromic craniosynostosisLong-term functionLarge population studiesCranial vaultHigh motor coordinationMotor achievementsUnilateral coronal synostosisFull-scale intelligence quotientIndependent predictorsFemale patientsStudy cohortNeurodevelopmental assessmentAverage intelligence quotient scoresMean ageControl subjectsNeurocognitive outcomesIntelligence quotient scoresRadiographic Predictors of FACE-Q Outcomes Following Non-Operative Orbital Floor Fracture Management.
Gabrick K, Smetona J, Iyengar R, Dinis J, Chouiari F, Peck CJ, Persing J, Alperovich M. Radiographic Predictors of FACE-Q Outcomes Following Non-Operative Orbital Floor Fracture Management. Journal Of Craniofacial Surgery 2020, 31: e388-e391. PMID: 32176015, DOI: 10.1097/scs.0000000000006356.Peer-Reviewed Original ResearchConceptsOrbital floor fracture managementOrbital floor fracturesPercent of patientsNon-operative managementPsychosocial distressFloor fracturesRadiographic findingsFracture managementMaxillary sinusYale-New Haven HospitalRight-sided fracturesAppearance-related psychosocial distressInferior rectus muscleLong-term outcomesPatient-reported questionnaireRectus muscle belliesMultiple surgical subspecialtiesNew Haven HospitalMean fracture areaBony injuriesInferior rectusOperative indicationsClinical findingsCommon injuriesMean durationAssessing Facial Asymmetry in Postoperative Patients With Unilateral Coronal Craniosynostosis.
Gabrick KS, Wu RT, Singh A, Bartlett SP, Taylor JA, Persing JA, Alperovich M. Assessing Facial Asymmetry in Postoperative Patients With Unilateral Coronal Craniosynostosis. Journal Of Craniofacial Surgery 2020, 31: 1000-1005. PMID: 32176017, DOI: 10.1097/scs.0000000000006355.Peer-Reviewed Original ResearchConceptsUnilateral craniosynostosisPatient-reported outcomesFacial asymmetrySurgical correctionPatient-reported outcome scoresPercent of patientsOrbital dystopiaSchool-aged patientsDysmorphic facial featuresUnilateral coronal craniosynostosisChin point deviationPostoperative patientsOutcome scoresChildren's HospitalPreoperative deformityPearson correlationPatientsAverage ageCranial base angulationRoot angulationOverall facial asymmetryNasal rootAngulationCoronal craniosynostosisHospitalClassification of Subtypes of Crouzon Syndrome Based on the Type of Vault Suture Synostosis.
Lu X, Sawh-Martinez R, Forte AJ, Wu R, Cabrejo R, Wilson A, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Classification of Subtypes of Crouzon Syndrome Based on the Type of Vault Suture Synostosis. Journal Of Craniofacial Surgery 2020, 31: 678-684. PMID: 32068731, DOI: 10.1097/scs.0000000000006173.Peer-Reviewed Original ResearchConceptsClass IIICrouzon syndromeClass IClass IISuture involvementSuture synostosisSimilar craniofacial characteristicsComputed tomography scanClassification of subtypesSurgical interventionMorphology of patientsAnatomic deformityTomography scanSurgical techniqueCT scanDifferent subtypesSagittal synostosisSyndromeClass IVPremature closureCraniofacial characteristicsSevere craniofacial malformationsCranial base lengthSynostosisDifferent pathologies
2019
Analysis of Airway and Midface in Crouzon Syndromes
Forte AJ, Lu X, Hashim PW, Steinbacher DM, Alperovich M, Persing JA, Alonso N. Analysis of Airway and Midface in Crouzon Syndromes. Annals Of Plastic Surgery 2019, Publish Ahead of Print: &na;. PMID: 30633021, DOI: 10.1097/sap.0000000000001740.Peer-Reviewed Original ResearchConceptsPharyngeal airway volumeComputed tomography scanAirway volumeControl subjectsTomography scanCrouzon syndromeAge-matched control subjectsAnalysis of airwaysSevere respiratory impairmentNasal airway volumePosterior pharyngeal wallEarly mixed dentitionCrouzon groupSurgical interventionRespiratory impairmentUpper airwaySoft tissue measurementsPharyngeal wallPosterior tongueMixed dentitionAirwayPatientsSyndromeVolumetric assessmentT-testAssociation of Regional Cranial Base Deformity and Ultimate Structure in Crouzon Syndrome.
Lu X, Jorge Forte A, Sawh-Martinez R, Wu R, Cabrejo R, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Association of Regional Cranial Base Deformity and Ultimate Structure in Crouzon Syndrome. Plastic & Reconstructive Surgery 2019, 143: 1233e-1243e. PMID: 31136487, DOI: 10.1097/prs.0000000000005643.Peer-Reviewed Original ResearchMandibular Spatial Reorientation and Morphological Alteration of Crouzon and Apert Syndrome.
Lu X, Sawh-Martinez R, Forte AJ, Wu R, Cabrejo R, Wilson A, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Mandibular Spatial Reorientation and Morphological Alteration of Crouzon and Apert Syndrome. Annals Of Plastic Surgery 2019, 83: 568-582. PMID: 31008788, DOI: 10.1097/sap.0000000000001811.Peer-Reviewed Original ResearchUnderstanding the Learning Disabilities Linked to Sagittal Craniosynostosis
Cabrejo R, Lacadie C, Brooks E, Beckett J, Sun A, Yang J, Chuang C, Eilbott J, Duncan C, Steinbacher D, Alperovich M, Ventola P, Pelphrey K, Constable T, Persing J. Understanding the Learning Disabilities Linked to Sagittal Craniosynostosis. Journal Of Craniofacial Surgery 2019, 30: 497-502. PMID: 30676447, DOI: 10.1097/scs.0000000000005194.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderFunctional magnetic resonance imagingSagittal nonsyndromic craniosynostosisSagittal craniosynostosisDifferent neural connectionsPrimary visual cortexVisual association cortexMagnetic resonance imagingStatistical parametric mappingDeficit hyperactivity disorderBrodmann area 11Association cortexVisual cortexResonance imagingNeurocognitive deficitsNeural connectionsPatientsFMRI scansHyperactivity disorderNonsyndromic craniosynostosisParametric mappingControl adolescentsAuditory processingArea 11CraniosynostosisSpatial and temporal changes of midface in Apert’s syndrome
Lu X, Forte AJ, Sawh-Martinez R, Wu R, Cabrejo R, Wilson A, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Spatial and temporal changes of midface in Apert’s syndrome. Journal Of Plastic Surgery And Hand Surgery 2019, 53: 130-137. PMID: 30782083, DOI: 10.1080/2000656x.2018.1541324.Peer-Reviewed Original Research
2018
Orbit, zygoma, and maxilla growth patterns in Crouzon syndrome
Lu X, Forte AJ, Sawh-Martinez R, Wu R, Cabrejo R, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Orbit, zygoma, and maxilla growth patterns in Crouzon syndrome. International Journal Of Oral And Maxillofacial Surgery 2018, 48: 309-321. PMID: 30389113, DOI: 10.1016/j.ijom.2018.10.013.Peer-Reviewed Original ResearchConceptsCrouzon syndromeCT scanAnteroposterior lengthWidth of maxillaPreoperative CT scanMonths-2 yearsMonths of agePrincipal deformityControl subjectsGlobe projectionAge subgroupsMaxillary wideningSecondary deformitiesOrbital wallAnterior protrusionSyndromeFacial malformationsMonthsDeformityAnteroposterior positionZygomatic regionCranial baseZygomaMalformationsMaterialise software
2016
Outpatient Alveolar Bone Grafting
Farber SJ, Runyan CM, Stern MJ, Massie JP, Alperovich M, Flores RL. Outpatient Alveolar Bone Grafting. Journal Of Craniofacial Surgery 2016, 27: 1661-1664. PMID: 27438449, DOI: 10.1097/scs.0000000000002899.Peer-Reviewed Original ResearchConceptsAlveolar bone graftTotal direct costsVariable direct costsInpatient stayObservation groupSite painDirect costsOutpatient costsRetrospective single-institution reviewDonor site painGroup of patientsSame-day dischargeSingle-institution reviewPostoperative inpatient stayOperating room costsCost-efficient treatmentHospital stayInpatient costsOutpatient groupTrephine techniqueAlveolar boneABG surgeryBone graftStayRoom costsLong-Term Surgical and Speech Outcomes Following Palatoplasty in Patients With Treacher–Collins Syndrome
Golinko MS, LeBlanc EM, Hallett AM, Alperovich M, Flores RL. Long-Term Surgical and Speech Outcomes Following Palatoplasty in Patients With Treacher–Collins Syndrome. Journal Of Craniofacial Surgery 2016, 27: 1408-1411. PMID: 27607112, DOI: 10.1097/scs.0000000000002821.Peer-Reviewed Original ResearchConceptsTreacher Collins syndromeVelopharyngeal dysfunctionCleft palateSurgical outcomesSpeech outcomesSpeech pathologistsCleft palate typeChallenging patient populationMajority of patientsCleft palate repairTime of palatoplastyLong-term speechPruzansky classificationVeau IVeau IIVeau IIIFurther surgeryPharyngeal surgeryUnderwent repairRetrospective reviewPatient populationSingle institutionPalate repairHigh incidencePatients