2025
Protein as a preoperative predictor – Impact of hypoalbuminemia on 30-day outcomes of breast reduction surgery
Knoedler S, Klimitz F, Diatta F, Perozzo F, Sofo G, Alfertshofer M, Cherubino M, Mayer H, Panayi A, Kim B, Pomahac B, Kauke-Navarro M. Protein as a preoperative predictor – Impact of hypoalbuminemia on 30-day outcomes of breast reduction surgery. Journal Of Plastic Reconstructive & Aesthetic Surgery 2025, 100: 144-152. DOI: 10.1016/j.bjps.2024.11.011.Peer-Reviewed Original ResearchBreast reduction surgeryImpact of hypoalbuminemiaReduction surgeryBody mass indexPostoperative complicationsSurgical outcomesMass indexAmerican College of Surgeons National Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseAssociated with adverse surgical outcomesPredictor of postoperative complicationsIncreased risk of complicationsQuality Improvement Program databasePreoperative nutritional assessmentSuperficial incisional infectionNormal albumin levelsBiomarkers of malnutritionHigher body mass indexAdverse surgical outcomesRisk of complicationsImprove surgical outcomesChronic obstructive pulmonary diseaseMultivariate logistic regressionObstructive pulmonary disease
2024
Risk Factors and Outcomes after Surgery for Malignant Neoplasm of the Parotid Gland: An ACS-NSQIP Study
Knoedler L, Knoedler S, Hoch C, Safi A, Wollenberg B, Alfertshofer M, Pomahac B, Kauke-Navarro M, Clune J. Risk Factors and Outcomes after Surgery for Malignant Neoplasm of the Parotid Gland: An ACS-NSQIP Study. Journal Of Plastic Reconstructive & Aesthetic Surgery 2024 PMID: 39448324, DOI: 10.1016/j.bjps.2024.09.067.Peer-Reviewed Original ResearchBlood urea nitrogenRisk factorsRenal failureParotid glandMalignant neoplasmsAmerican College of Surgeons National Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseAssociated with higher creatinineNational Surgical Quality Improvement Program databaseMicrosurgical proceduresPre-operative risk factorsQuality Improvement Program databaseRisk of postoperative adverse eventsBlood urea nitrogen levelsHigher ASA classPostoperative adverse eventsOccurrence of complicationsPost-surgical outcomesTumor resectionComplication rateFlap surgeryPostoperative outcomesACS-NSQIPASA classHigher creatinineSurgical Management of Breast Capsular Contracture—A Multi-institutional Data Analysis of Risk Factors for Early Complications
Knoedler S, Knoedler L, Boroumand S, Alfertshofer M, Diatta F, Sofo G, Huelsboemer L, Hansen F, Könneker S, Kim B, Perozzo F, Ayyala H, Allam O, Pomahac B, Kauke-Navarro M. Surgical Management of Breast Capsular Contracture—A Multi-institutional Data Analysis of Risk Factors for Early Complications. Aesthetic Plastic Surgery 2024, 1-12. PMID: 38926252, DOI: 10.1007/s00266-024-04203-x.Peer-Reviewed Original ResearchRisk factorsPostoperative complicationsCC surgeryInpatient settingMedical complicationsAmerican College of Surgeons National Surgical Quality Improvement Program databaseRisk factors of postoperative complicationsSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseImplant-based breast surgeryMultivariate analysisPreoperative diagnosis of hypertensionFactors of postoperative complicationsQuality Improvement Program databaseLevel of Evidence IIIThis journalEvidence-Based Medicine ratingsAnalysis of risk factorsDay complication ratesDays follow-upEvidence IIIThis journalLevel of evidenceSurgical adverse eventsDiagnosis of hypertensionMulti-institutional dataTreatment of CC
2023
Racial disparities in surgical outcomes after mastectomy in 223 000 female breast cancer patients: a retrospective cohort study
Knoedler S, Kauke-Navarro M, Knoedler L, Friedrich S, Matar D, Diatta F, Mookerjee V, Ayyala H, Wu M, Kim B, Machens H, Pomahac B, Orgill D, Broer P, Panayi A. Racial disparities in surgical outcomes after mastectomy in 223 000 female breast cancer patients: a retrospective cohort study. International Journal Of Surgery 2023, 110: 684-699. PMID: 38052017, PMCID: PMC10871660, DOI: 10.1097/js9.0000000000000909.Peer-Reviewed Original ResearchAmerican Indian/Alaska Native womenBreast cancer patientsAlaska Native womenSurgical complicationsRadical mastectomyPartial mastectomyCancer patientsSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseFemale breast cancer patientsNon-home dischargeRetrospective cohort studyImprovement Program databaseLikelihood of readmissionBreast cancer mortalityBreast cancer surgeryAfrican American patientsAmerican Indians/Alaska NativesBlack/African AmericanNative Hawaiian/Pacific IslanderComplication occurrencePerioperative complicationsPerioperative outcomesAdverse eventsAn ACS-NSQIP Data Analysis of 30-Day Outcomes Following Surgery for Bell’s Palsy
Knoedler S, Knoedler L, Hoch C, Kauke-Navarro M, Kehrer A, Friedman L, Prantl L, Machens H, Orgill D, Panayi A. An ACS-NSQIP Data Analysis of 30-Day Outcomes Following Surgery for Bell’s Palsy. Journal Of Craniofacial Surgery 2023, 35: 23-28. PMID: 37695075, PMCID: PMC10841222, DOI: 10.1097/scs.0000000000009739.Peer-Reviewed Original ResearchBell's palsyHospital stayPostoperative outcomesSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseFuture large-scale prospective studiesDiagnosis of BPQuality Improvement Program databaseLarge-scale prospective studiesImprovement Program databasePoor postoperative outcomesRoutine laboratory valuesOutcome of surgeryMulti-institutional analysisBlood urea nitrogenMulti-institutional databaseMajority of proceduresMulti-institutional studyQuality of careCommon comorbiditiesFrequent complicationPerioperative protocolComplication rateMedical complicationsPreoperative evaluationIncidence and Risk Factors of Postoperative Complications After Rhinoplasty: A Multi-Institutional ACS-NSQIP Analysis
Knoedler S, Knoedler L, Wu M, Haug V, Broer P, Kauke-Navarro M, Hundeshagen G, Prantl L, Orgill D, Panayi A. Incidence and Risk Factors of Postoperative Complications After Rhinoplasty: A Multi-Institutional ACS-NSQIP Analysis. Journal Of Craniofacial Surgery 2023, 34: 1722-1726. PMID: 37487058, DOI: 10.1097/scs.0000000000009553.Peer-Reviewed Original ResearchConceptsLow serum albuminSurgical adverse eventsAdverse eventsRisk factorsPostoperative outcomesASA scoreComplication rateMale sexSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseQuality Improvement Program databasePreoperative nutritional optimizationSuperficial incisional infectionAverage patient ageHigher ASA scoreImprovement Program databasePreoperative laboratory valuesACS-NSQIP AnalysisMulti-institutional analysisSingle-institution reportsIncisional infectionPostoperative complicationsPreoperative albuminComplication occurrenceMost patientsThe surgical patient of yesterday, today, and tomorrow—a time-trend analysis based on a cohort of 8.7 million surgical patients
Knoedler S, Matar D, Friedrich S, Knoedler L, Haug V, Hundeshagen G, Kauke-Navarro M, Kneser U, Pomahac B, Orgill D, Panayi A. The surgical patient of yesterday, today, and tomorrow—a time-trend analysis based on a cohort of 8.7 million surgical patients. International Journal Of Surgery 2023, 109: 2631-2640. PMID: 37788019, PMCID: PMC10498871, DOI: 10.1097/js9.0000000000000511.Peer-Reviewed Original ResearchConceptsSurgical patientsMedian ageMedian BMISurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseACS-NSQIP databaseImprovement Program databaseObesity class IProportion of patientsCohort of patientsPrevalence of diabetesType 2 diabetesGlobal healthcare deliveryFuture surgical careField of surgeryTime trend analysisPatient ageSurgical cohortDiabetes prevalenceProgram databaseSurgical careAmerican CollegeGeneral populationPatientsEarly Outcomes and Risk Factors in Orthognathic Surgery for Mandibular and Maxillary Hypo- and Hyperplasia: A 13-Year Analysis of a Multi-Institutional Database
Knoedler S, Baecher H, Hoch C, Obed D, Matar D, Rendenbach C, Kim B, Harhaus L, Kauke-Navarro M, Hundeshagen G, Knoedler L, Orgill D, Panayi A. Early Outcomes and Risk Factors in Orthognathic Surgery for Mandibular and Maxillary Hypo- and Hyperplasia: A 13-Year Analysis of a Multi-Institutional Database. Journal Of Clinical Medicine 2023, 12: 1444. PMID: 36835979, PMCID: PMC9965345, DOI: 10.3390/jcm12041444.Peer-Reviewed Original ResearchMulti-institutional databaseRisk factorsOrthognathic surgeryJaw surgeryAdverse eventsSurgical complicationsSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseSingle-institutional reportSuperficial incisional infectionPostoperative adverse eventsACS-NSQIP databaseImprovement Program databaseCommon surgical complicationPositive safety profileHigh complication rateSingle surgeon's experienceSingle-jaw surgeryNovel risk factorsDouble-jaw surgeryEqual gender distributionWarrants further investigationIncisional infectionPostoperative complications
2022
30-Day Postoperative Outcomes in Adults with Obstructive Sleep Apnea Undergoing Upper Airway Surgery
Knoedler S, Knoedler L, Baecher H, Kauke-Navarro M, Obed D, Hoch C, Diehm Y, Vosler P, Harréus U, Kneser U, Panayi A. 30-Day Postoperative Outcomes in Adults with Obstructive Sleep Apnea Undergoing Upper Airway Surgery. Journal Of Clinical Medicine 2022, 11: 7371. PMID: 36555986, PMCID: PMC9783895, DOI: 10.3390/jcm11247371.Peer-Reviewed Original ResearchObstructive sleep apneaOSA surgeryPostoperative outcomesMedical complicationsSleep apneaSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseMulti-institutional national databaseQuality Improvement Program databaseUpper airway surgeryTotal complication rateHistory of diabetesImprovement Program databasePositive safety profileAlkaline phosphatasePostoperative complicationsComplication ratePostoperative periodAirway surgeryFrequent comorbiditiesMale sexSafety profileUpper airwaySurgery outcomesChronic disordersPerioperative Outcomes and Risk Profile of 4730 Cosmetic Breast Surgery Cases in Academic Institutions: An ACS-NSQIP Analysis
Knoedler S, Kauke-Navarro M, Haug V, Broer P, Pomahac B, Knoedler L, Panayi A. Perioperative Outcomes and Risk Profile of 4730 Cosmetic Breast Surgery Cases in Academic Institutions: An ACS-NSQIP Analysis. Aesthetic Surgery Journal 2022, 43: 433-451. PMID: 36472232, DOI: 10.1093/asj/sjac320.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseCosmetic breast surgeryObstructive pulmonary diseaseRisk factorsSurgical complicationsPulmonary diseaseSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseMulti-institutional national databaseMultiple proceduresQuality Improvement Program databaseImprovement Program databaseIndependent risk factorCongestive heart failurePositive safety profileObesity class 1ACS-NSQIP AnalysisAnesthesiology scoreBreast surgery casesPerioperative outcomesPerioperative protocolPostoperative outcomesClinical patternHeart failureFemale patientsThe modified 5-item frailty index is a predictor of perioperative risk in breast reconstruction: An analysis of 40,415 cases
Panayi AC, Foroutanjazi S, Parikh N, Haug V, Kauke-Navarro M, Diehm YF, Pomahac B. The modified 5-item frailty index is a predictor of perioperative risk in breast reconstruction: An analysis of 40,415 cases. Journal Of Plastic Reconstructive & Aesthetic Surgery 2022, 75: 2941-2954. PMID: 35599223, DOI: 10.1016/j.bjps.2022.04.035.Peer-Reviewed Original ResearchConceptsImplant-based reconstructionBreast reconstructionMFI-5Unplanned readmissionPostoperative outcomesSurgical complicationsMedical complicationsMFI scoreRisk predictorsSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseBreast reconstruction patientsFrailty index-5Powerful risk predictorImprovement Program databasePreoperative risk stratificationStrong risk predictorAutologous breast reconstructionAdverse surgical outcomesType of reconstructionHigh rateFrail patientsHospital stayPerioperative riskRacial disparities in short-term outcomes after breast reduction surgery–A National Surgical Quality Improvement Project Analysis with 23,268 patients using Propensity Score Matching
Haug V, Kadakia N, Wang AT, Dorante MI, Panayi AC, Kauke-Navarro M, Hundeshagen G, Diehm YF, Fischer S, Hirche C, Kneser U, Pomahac B. Racial disparities in short-term outcomes after breast reduction surgery–A National Surgical Quality Improvement Project Analysis with 23,268 patients using Propensity Score Matching. Journal Of Plastic Reconstructive & Aesthetic Surgery 2022, 75: 1849-1857. PMID: 35131191, DOI: 10.1016/j.bjps.2022.01.001.Peer-Reviewed Original ResearchConceptsBreast reduction surgeryPropensity scoreSurgical complicationsPreoperative variablesReduction surgerySurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseMajor surgical complicationsImprovement Program databaseMinor surgical complicationsShort-term outcomesNon-white patientsNumber of patientsEthnic health inequalitiesNon-white cohortsPostoperative outcomesDiabetes mellitusMajor complicationsMedical complicationsSurgical outcomesPatient ethnicityProgram databaseInclusion criteriaSurgical care
2021
The modified 5-item frailty index is a predictor of perioperative risk in head and neck microvascular reconstruction: An analysis of 3795 cases
Panayi AC, Haug V, Kauke-Navarro M, Foroutanjazi S, Diehm YF, Pomahac B. The modified 5-item frailty index is a predictor of perioperative risk in head and neck microvascular reconstruction: An analysis of 3795 cases. American Journal Of Otolaryngology 2021, 42: 103121. PMID: 34171698, DOI: 10.1016/j.amjoto.2021.103121.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnastomosis, SurgicalDiabetes MellitusFemaleForecastingFrailtyHeadHeart FailureHumansHypertensionLength of StayMaleMicrovesselsMiddle AgedNeckOperative TimePlastic Surgery ProceduresPostoperative ComplicationsPulmonary Disease, Chronic ObstructiveSeverity of Illness IndexSurgical FlapsTreatment OutcomeConceptsNeck microvascular reconstructionMFI-5Microvascular reconstructionMFI scoreSubgroup analysisNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseChronic obstructive pulmonary diseaseFrailty index-5Non-home dischargeImprovement Program databaseAverage operative timeCongestive heart failureObstructive pulmonary diseasePost-operative outcomesPre-operative identificationPost-operative supportTerms of demographicsHospital stayPerioperative riskUnplanned readmissionHome dischargePostoperative outcomesYounger patientsFrailty index
2020
Combined (endo-)vascular intervention and microsurgical lower extremity free flap reconstruction—A propensity score matching analysis in 5386 ACS-NSQIP patients
Haug V, Kadakia N, Panayi AC, Kauke M, Hundeshagen G, Diehm Y, Fischer S, Hirche C, Kneser U, Pomahac B. Combined (endo-)vascular intervention and microsurgical lower extremity free flap reconstruction—A propensity score matching analysis in 5386 ACS-NSQIP patients. Journal Of Plastic Reconstructive & Aesthetic Surgery 2020, 74: 1031-1040. PMID: 33436337, DOI: 10.1016/j.bjps.2020.10.045.Peer-Reviewed Original ResearchConceptsFree flap reconstructionLower extremity free flap reconstructionFlap reconstructionLimb amputationNational Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseAnesthesiology physical status classificationQuality Improvement Program databaseMicrosurgical free flap reconstructionPropensity scoreACS-NSQIP patientsLower limb perfusionPreoperative steroid usePropensity-matched cohortImprovement Program databaseModifiable risk factorsPeripheral artery diseasePhysical status classificationCareful preoperative assessmentSick patient populationLower limb amputationLower extremity salvageLower limb reconstructionFree flap transferFree tissue transfer