2020
Recognizing Emotional Expression as an Outcome Measure After Face Transplant
Dorante M, Kollar B, Obed D, Haug V, Fischer S, Pomahac B. Recognizing Emotional Expression as an Outcome Measure After Face Transplant. JAMA Network Open 2020, 3: e1919247. PMID: 31940037, PMCID: PMC6991259, DOI: 10.1001/jamanetworkopen.2019.19247.Peer-Reviewed Original Research
2019
Twenty-Four-Hour Ex Vivo Perfusion with Acellular Solution Enables Successful Replantation of Porcine Forelimbs.
Krezdorn N, Macleod F, Tasigiorgos S, Turk M D M, Wo L, Kiwanuka B A H, Lopdrup B I D R, Kollar B, Edelman E, Pomahac B. Twenty-Four-Hour Ex Vivo Perfusion with Acellular Solution Enables Successful Replantation of Porcine Forelimbs. Plastic & Reconstructive Surgery 2019, 144: 608e-618e. PMID: 31568296, DOI: 10.1097/prs.0000000000006084.Peer-Reviewed Original Research
2017
Seasonal Variability Precipitating Hand Transplant Rejection?
Lopdrup R, Turk M, Win T, Marty F, Molway D, Tullius S, Pomahac B, Talbot S. Seasonal Variability Precipitating Hand Transplant Rejection? Transplantation 2017, 101: e313. PMID: 28930103, DOI: 10.1097/tp.0000000000001877.Peer-Reviewed Original ResearchThe Effects of Lip-Closure Exercise on Lip Strength and Function Following Full Facial Transplantation: A Case Report
Perry B, Richburg B, Pomahac B, Bueno E, Green J. The Effects of Lip-Closure Exercise on Lip Strength and Function Following Full Facial Transplantation: A Case Report. American Journal Of Speech-Language Pathology 2017, 26: 682-686. PMID: 28654949, DOI: 10.1044/2017_ajslp-16-0101.Peer-Reviewed Original ResearchConceptsLip strengthFacial transplantationPatient-reported outcomesFull facial transplantationRange of motionStrength training exercisesSevere facial disfigurementPreliminary findingsExercise programAdditional researchCase reportOutcome measuresClinical measuresSingle patientMotor impairmentTransplantationClinical casesPatientsFacial disfigurementExerciseEfficacyNew optionsSpeech intelligibilityExpressionSwallowingOutcomes of Solid Organ Transplants After Simultaneous Solid Organ and Vascularized Composite Allograft Procurements
Aycart M, Alhefzi M, Sharma G, Krezdorn N, Bueno E, Talbot S, Carty M, Tullius S, Pomahac B. Outcomes of Solid Organ Transplants After Simultaneous Solid Organ and Vascularized Composite Allograft Procurements. Transplantation 2017, 101: 1381-1386. PMID: 27140518, PMCID: PMC6347371, DOI: 10.1097/tp.0000000000001262.Peer-Reviewed Original ResearchMeSH KeywordsAdultComposite Tissue AllograftsFacial TransplantationFemaleGraft SurvivalHumansMaleMiddle AgedOperative TimeOrgan TransplantationPostoperative ComplicationsRegistriesRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTissue and Organ HarvestingTissue DonorsTreatment OutcomeUnited StatesYoung AdultConceptsGraft survival ratesSolid organsSurvival rateLiver recipientsTransplant recipientsAllograft procurementSolid organ allograftsSolid organ transplantsBrain-dead donorsLong-term outcomesShort-term resultsHeart recipientsIntraoperative parametersDonor surgeryOperative durationOrgan allograftsPostoperative outcomesScientific RegistryTransplantation outcomesPopulation of subjectsCase reportOperative characteristicsUnknown causeNationwide analysisOrgan transplantsFirst Lower Two-Thirds Osteomyocutaneous Facial Allograft Perfused by a Unilateral Facial Artery
Fischer S, Lee T, Krezdorn N, Alhefzi M, Kueckelhaus M, Bueno E, Pomahac B. First Lower Two-Thirds Osteomyocutaneous Facial Allograft Perfused by a Unilateral Facial Artery. Plastic & Reconstructive Surgery 2017, 139: 1175e-1183e. PMID: 28445377, DOI: 10.1097/prs.0000000000003288.Peer-Reviewed Original ResearchConceptsFacial arteryFacial allograftImmunosuppressive therapyRejection episodesAirway volumeVenous outflowCLINICAL QUESTION/LEVELDual immunosuppressive therapyFacial allotransplantationTwo-thirdsMaintenance therapyMycophenolate mofetilSteroid pulseArtery anastomosisSurgical durationFacial functionTracheostomy tubeContralateral sideVascular anastomosisSubmental arteryTransplantationArteryAllograftsVascularization patternFacial formAcellular Hypothermic Extracorporeal Perfusion Extends Allowable Ischemia Time in a Porcine Whole Limb Replantation Model
Kueckelhaus M, Dermietzel A, Alhefzi M, Aycart M, Fischer S, Krezdorn N, Wo L, Maarouf O, Riella L, Abdi R, Bueno E, Pomahac B. Acellular Hypothermic Extracorporeal Perfusion Extends Allowable Ischemia Time in a Porcine Whole Limb Replantation Model. Plastic & Reconstructive Surgery 2017, 139: 922e-932e. PMID: 28350667, DOI: 10.1097/prs.0000000000003208.Peer-Reviewed Original ResearchReflections on a Decade of Face Transplantation
Giatsidis G, Sinha I, Pomahac B. Reflections on a Decade of Face Transplantation. Annals Of Surgery 2017, 265: 841-846. PMID: 28032849, DOI: 10.1097/sla.0000000000001760.Peer-Reviewed Original ResearchConceptsFace transplantationSci-fi novelsEthical discussionPersonal strugglesSocial beliefsFace transplantSocietal implicationsMedical discoveriesMedical innovationScienceFace restorationPublic opinionHigh-risk trajectoriesTodayLong wayMedical communityRegulatory frameworkBeliefsStruggleSocietyReflectionAnswersQuestionsDiscussionAnniversary
2016
Guillain–Barré syndrome associated with resistant cytomegalovirus infection after face transplantation
Alhefzi M, Aycart M, Bueno E, Kueckelhaus M, Fischer S, Snook R, Sharfuddin A, Hadad I, Malla P, Amato A, Pomahac B, Marty F. Guillain–Barré syndrome associated with resistant cytomegalovirus infection after face transplantation. Transplant Infectious Disease 2016, 18: 288-292. PMID: 26910286, DOI: 10.1111/tid.12516.Peer-Reviewed Original ResearchConceptsGuillain-Barré syndromeLower extremity paresthesiasResistant cytomegalovirus infectionLower extremity weaknessSensorimotor axonal polyneuropathyExtremity weaknessIntravenous immunoglobulinAxonal polyneuropathyCMV infectionCytomegalovirus infectionExtremity paresthesiasImmune controlAxonal formTransplantationFacial allograftFace transplantationElectrophysiological evidenceMonthsSyndromeInfectionParesthesiaPolyneuropathyAllograftsRecurrenceCMVFunctional Outcomes after Bilateral Hand Transplantation
Singh M, Sisk G, Carty M, Sampson C, Blazar P, Dyer G, Earp B, Pribaz J, Pomahac B, Talbot S. Functional Outcomes after Bilateral Hand Transplantation. Plastic & Reconstructive Surgery 2016, 137: 185-189. PMID: 26710022, DOI: 10.1097/prs.0000000000001872.Peer-Reviewed Original ResearchConceptsBilateral hand transplantationHand transplantationFunctional outcomeHand scoreOutcome measuresShort Form-36 Health SurveyCLINICAL QUESTION/LEVELBilateral hand transplantMid-forearm levelFirst successful hand transplantationFunctional outcome measuresHand transplantHealth SurveyFunctional gainsTherapy measuresSystem scoreTransplantationPatientsScore systemMultiple studiesOutcomesScoresObjective scoresDisabilityConsiderable variability
2015
Noninvasive Monitoring of Immune Rejection in Face Transplant Recipients
Kueckelhaus M, Imanzadeh A, Fischer S, Kumamaru K, Alhefzi M, Bueno E, Wake N, Gerhard-Herman M, Rybicki F, Pomahac B. Noninvasive Monitoring of Immune Rejection in Face Transplant Recipients. Plastic & Reconstructive Surgery 2015, 136: 1082-1089. PMID: 26505709, DOI: 10.1097/prs.0000000000001703.Peer-Reviewed Original ResearchConceptsFace transplant recipientsTransplant recipientsChronic rejectionCLINICAL QUESTION/LEVELAllograft biopsy specimensTotal vessel diameterSolid organ allograftsAllograft lossOrgan allograftsPostsurgical monitoringFlap arteryControl subjectsBiopsy specimensIntimal thicknessClinical signsRadial arteryThicker intimaUltrasound biomicroscopyFacial arteryMedia thicknessHistologic analysisImmune rejectionArteryRecipientsInterobserver correlationInitial Experience of Dual Maintenance Immunosuppression With Steroid Withdrawal in Vascular Composite Tissue Allotransplantation
Diaz-Siso J, Fischer S, Sisk G, Bueno E, Kueckelhaus M, Talbot S, Carty M, Treister N, Marty F, Milford E, Pomahac B, Tullius S. Initial Experience of Dual Maintenance Immunosuppression With Steroid Withdrawal in Vascular Composite Tissue Allotransplantation. American Journal Of Transplantation 2015, 15: 1421-1431. PMID: 25777324, DOI: 10.1111/ajt.13103.Peer-Reviewed Original ResearchConceptsAcute rejectionVCA recipientsMaintenance immunosuppressionSteroid-resistant acute rejectionLate acute rejectionSolid organ transplantationComposite tissue allotransplantationMaintenance steroidsTopical immunosuppressionCurrent immunosuppressionSteroid withdrawalBolus treatmentOrgan transplantationLow doseImmunosuppressionTissue allotransplantationInitial experienceFurther experienceSteroidsRecipientsTacrolimusPatientsTreatmentMonthsLow levels
2012
Psychosocial Changes 6 Months after Face Transplantation
Chang G, Pomahac B. Psychosocial Changes 6 Months after Face Transplantation. Journal Of The Academy Of Consultation-Liaison Psychiatry 2012, 54: 367-371. PMID: 23194929, PMCID: PMC3593952, DOI: 10.1016/j.psym.2012.07.012.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdultFacial TransplantationFemaleFollow-Up StudiesHumansInterpersonal RelationsInterview, PsychologicalLinear ModelsMaleOutcome Assessment, Health CarePostoperative PeriodPsychiatric Status Rating ScalesQuality of LifeSelf ConceptSurveys and QuestionnairesTime FactorsConceptsMental healthComprehensive psychiatric assessmentChanges 6 monthsCommon clinical practiceFull facial transplantationNovel surgical procedureMOS SF-12Facial transplantationOverall mental healthTransplantation programPsychosocial statusSurgical proceduresEQ-5D.Life measuresPsychiatric assessmentClinical practiceTransplantationPsychosocial changesFace transplantationMonthsRecipientsSurgeryMeasures 3Assessment protocolSame periodAbdominal wall reconstruction using a non-cross-linked porcine dermal scaffold: a follow-up study
Diaz-Siso J, Bueno E, Pomahac B. Abdominal wall reconstruction using a non-cross-linked porcine dermal scaffold: a follow-up study. Hernia 2012, 17: 37-44. PMID: 22707311, DOI: 10.1007/s10029-012-0927-0.Peer-Reviewed Original ResearchConceptsAbdominal wall reconstructionWall reconstructionMulti-organ failureLong-term outcomesLarger patient populationComplicated abdominal wallAbdominal wall defectAbdominal wall repairMean followMost patientsAnalysis of demographicsPatient populationIntraperitoneal techniqueSurgical techniqueComplex abdominal wall defectsAbdominal wallProsthetic meshPatientsComplicationsWall repairSuccessful outcomeConclusionsThis studyWall defectDermal scaffoldsInitial report
2008
Routine Use of Wound Vacuum-Assisted Closure Does Not Allow Coverage Delay for Open Tibia Fractures
Bhattacharyya T, Mehta P, Smith M, Pomahac B. Routine Use of Wound Vacuum-Assisted Closure Does Not Allow Coverage Delay for Open Tibia Fractures. Plastic & Reconstructive Surgery 2008, 121: 1263-1266. PMID: 18349645, DOI: 10.1097/01.prs.0000305536.09242.a6.Peer-Reviewed Original ResearchConceptsOpen tibia fracturesVacuum-assisted closureSoft tissue coverageTibia fracturesInfection rateRoutine useGrade IIIB open fracturesOpen fracturesVacuum-assisted closure therapyVacuum-assisted closure deviceOpen fracture woundsOverall infection ratePrevention of infectionRate of infectionGreater mean timeType of fixationSurgical debridementFracture woundsTrauma registryClosure therapyFlap coverageInfected patientsMedical recordsClosure devicePositive cultures