2024
Immune modulation in transplant medicine: a comprehensive review of cell therapy applications and future directions
Knoedler L, Dean J, Diatta F, Thompson N, Knoedler S, Rhys R, Sherwani K, Ettl T, Mayer S, Falkner F, Kilian K, Panayi A, Iske J, Safi A, Tullius S, Haykal S, Pomahac B, Kauke-Navarro M. Immune modulation in transplant medicine: a comprehensive review of cell therapy applications and future directions. Frontiers In Immunology 2024, 15: 1372862. PMID: 38650942, PMCID: PMC11033354, DOI: 10.3389/fimmu.2024.1372862.Peer-Reviewed Original ResearchConceptsRegulatory myeloid cellsSolid organ transplantationVascularized composite allotransplantationMesenchymal stromal cellsT cellsTransplant patientsCellular therapyChimeric antigen receptor T cellsTransplant surgerySide effectsIncreased risk of malignancyProgression to chronic rejectionAcute rejection ratesPerioperative treatment strategiesRegulatory T cellsPromote immune toleranceRisk of malignancySystemic side effectsRelated side effectsCell typesImprove transplant survivalCAR-TCell therapy applicationsImmunosuppressive regimensChronic rejection
2008
Facial Transplantation and Immunosuppressed Patients: A New Frontier in Reconstructive Surgery
Pomahac B, Aflaki P, Chandraker A, Pribaz J. Facial Transplantation and Immunosuppressed Patients: A New Frontier in Reconstructive Surgery. Transplantation 2008, 85: 1693-1697. PMID: 18580458, DOI: 10.1097/tp.0b013e318176b29e.Peer-Reviewed Original ResearchConceptsPartial face transplantationOrgan transplant recipientsFace transplantationTransplant recipientsLife-long immunosuppressionPatient selection criteriaRisk of malignancyComposite tissue transplantationFacial transplantationAlternative reconstructive methodImmunosuppressive regimenImmunosuppressive therapyAdditional immunosuppressionSurgical resectionImmunosuppressed patientsOrgan recipientsPatient populationWomen's HospitalReconstructive surgeryTransplantationIRB approvalSkin cancerReconstructive methodsControversial procedureTissue transplantation