Noninvasive Monitoring of Immune Rejection in Face Transplant Recipients
Kueckelhaus M, Imanzadeh A, Fischer S, Kumamaru K, Alhefzi M, Bueno E, Wake N, Gerhard-Herman M, Rybicki F, Pomahac B. Noninvasive Monitoring of Immune Rejection in Face Transplant Recipients. Plastic & Reconstructive Surgery 2015, 136: 1082-1089. PMID: 26505709, DOI: 10.1097/prs.0000000000001703.Peer-Reviewed Original ResearchConceptsFace transplant recipientsTransplant recipientsChronic rejectionCLINICAL QUESTION/LEVELAllograft biopsy specimensTotal vessel diameterSolid organ allograftsAllograft lossOrgan allograftsPostsurgical monitoringFlap arteryControl subjectsBiopsy specimensIntimal thicknessClinical signsRadial arteryThicker intimaUltrasound biomicroscopyFacial arteryMedia thicknessHistologic analysisImmune rejectionArteryRecipientsInterobserver correlationUtility of Sentinel Flaps in Assessing Facial Allograft Rejection
Kueckelhaus M, Fischer S, Lian C, Bueno E, Marty F, Tullius S, Pribaz J, Murphy G, Pomahac B. Utility of Sentinel Flaps in Assessing Facial Allograft Rejection. Plastic & Reconstructive Surgery 2015, 135: 250-258. PMID: 25255116, DOI: 10.1097/prs.0000000000000797.Peer-Reviewed Original ResearchConceptsFacial allograftRejection monitoringFasciocutaneous radial forearm flapCLINICAL QUESTION/LEVELSevere rejection episodesFurther surgical proceduresFacial allotransplantationFree fasciocutaneous radial forearm flapRadial forearm flapAxial blood supplyFunctional flapNonfacial sitesRejection episodesLimited skin areaSevere rejectionAllograft rejectionClinical findingsFacial dermatitisFrequent biopsiesBiopsy pairsBiopsy specimensHistologic evaluationSkin biopsiesBlood supplySurgical procedures