2015
Trends in Treatment Patterns and Outcomes for Ductal Carcinoma in Situ
Worni M, Akushevich I, Greenup R, Sarma D, Ryser M, Myers E, Hwang E. Trends in Treatment Patterns and Outcomes for Ductal Carcinoma in Situ. Journal Of The National Cancer Institute 2015, 107: djv263. PMID: 26424776, PMCID: PMC4707192, DOI: 10.1093/jnci/djv263.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBiomarkers, TumorBreast NeoplasmsCarcinoma, Intraductal, NoninfiltratingConfounding Factors, EpidemiologicDisease-Free SurvivalFemaleHumansMastectomyMastectomy, Modified RadicalMastectomy, SegmentalMiddle AgedNeoplasm GradingNeoplasm StagingOdds RatioProportional Hazards ModelsRadiotherapy, AdjuvantReceptors, EstrogenReceptors, ProgesteroneSEER ProgramSentinel Lymph Node BiopsySurvival AnalysisTreatment OutcomeUnited StatesConceptsOverall survivalTreatment patternsPre-invasive breast cancerSentinel lymph node biopsyCox proportional hazards regressionLocoregional treatment optionsNational treatment trendsEnd Results registryLymph node biopsyBreast cancer outcomesLong-term outcomesProportional hazards regressionPatient selection biasCochran-Armitage trend testInverse probability weightsDCIS patientsNode biopsyBilateral mastectomyDuctal carcinomaHazards regressionCancer outcomesTreatment optionsBreast cancerTreatment trendsLumpectomy
2013
New Treatment Paradigms for Patients with Ductal Carcinoma In Situ
Mackey A, Greenup R, Hwang E. New Treatment Paradigms for Patients with Ductal Carcinoma In Situ. Current Breast Cancer Reports 2013, 5: 86-98. DOI: 10.1007/s12609-013-0109-9.Peer-Reviewed Original ResearchDuctal carcinomaDiagnosis of DCISNew treatment paradigmMolecular prognostic toolsMagnitude of benefitDCIS subtypesAdjuvant treatmentClinical factorsActive surveillanceTreatment paradigmTreatment strategiesBreast cancerIndividualized therapyPrognostic toolHeterogeneous lesionsClinical diagnosisDCISPatientsCarcinomaInvasive potentialDiagnosisLumpectomyMalignancyTherapyLesions