Bulat A. Ziganshin, MD, PhD
Associate Research Scientist of Surgery (Cardiac Surgery)DownloadHi-Res Photo
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Cardiac Surgery
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Associate Research Scientist of Surgery (Cardiac Surgery)
Biography
Dr. Bulat A. Ziganshin is an Associate Research Scientist of Surgery (Cardiac Surgery) at Yale University School of Medicine. He is a Research Director at the Aortic Institute at Yale-New Haven Hospital. Dr. Ziganshin received his Medical Doctor (MD) Degree and a PhD Degree in Pharmacology from Kazan State Medical University (Kazan, Russia) where he also completed residency training in Cardiovascular Surgery. After completion of training, Dr. Ziganshin joined the faculty at Yale University in a clinical research capacity. Dr. Ziganshin’s primary research interests include aortic disease, genetics and genomics, cardiac surgery, pharmacology, and global health. He has published over 200 scientific manuscripts in peer-reviewed journals, as well as 19 chapters in textbooks, and co-authored five drug reference books. Since 2012 Dr. Ziganshin serves as an Associate Editor of AORTA Journal.
Appointments
Cardiac Surgery
Associate Research ScientistPrimary
Other Departments & Organizations
Education & Training
- PhD
- Kazan State Medical University, Pharmacology (2016)
- MD
- Kazan State Medical University, General Medicine (2007)
Research
Overview
Medical Research Interests
Aneurysm; Aortic Aneurysm, Thoracic; Aortic Diseases; Drugs, Investigational; Varicose Veins
Public Health Interests
Cardiovascular Diseases; Global Health
ORCID
0000-0002-5190-4654
Research at a Glance
Yale Co-Authors
Frequent collaborators of Bulat A. Ziganshin's published research.
Publications Timeline
A big-picture view of Bulat A. Ziganshin's research output by year.
Research Interests
Research topics Bulat A. Ziganshin is interested in exploring.
Mohammad Abdullah Zafar, MBBS
Sandip Mukherjee, MD, FACC
Allen Bale, MD
Jennifer M. Kwan, MD/PhD
John Elefteriades, MD
25Publications
211Citations
Aortic Aneurysm, Thoracic
Aneurysm
Publications
2024
Gene Commonality in Arterial Circuits Throughout the Body
Harling L, Zafar M, Ziganshin B, Elefteriades J. Gene Commonality in Arterial Circuits Throughout the Body. Aorta 2024 PMID: 39532283, DOI: 10.1055/s-0044-1791667.Peer-Reviewed Original ResearchIMPROVEMENT OF DIAGNOSTICS METHODOLOGY OF DIESEL ENGINE WITH COMMON RAIL FUEL SYSTEM IN FREE ACCELERATION MODE
Ibyatov R, Ziganshin B, Galeev D. IMPROVEMENT OF DIAGNOSTICS METHODOLOGY OF DIESEL ENGINE WITH COMMON RAIL FUEL SYSTEM IN FREE ACCELERATION MODE. Vestnik Of Kazan State Agrarin University 2024, 19: 67-74. DOI: 10.12737/2073-0462-2024-67-74.Peer-Reviewed Original ResearchConceptsAngle of inclinationCentrifugal forceChannel lengthFlow regime parametersInlet sectionCurved channelChannel wallsVelocity profilesLiquid flowInsert shapeGraphical dependencesRegime parametersGeometric characteristicsDispersion mediumMedium particlesExponent mFlow surfaceParabolic formDisk separationGap sizeVelocity diagramsNumerical calculationsCalculated resultsAcceleration modeNonlinear equationsEfficacy of beta blockers in patients with thoracic aortic aneurysm: meta-analysis of randomized controlled trials
Tanriverdi L, Barrett A, Kalyanasundaram A, Zafar M, Ziganshin B, Elefteriades J. Efficacy of beta blockers in patients with thoracic aortic aneurysm: meta-analysis of randomized controlled trials. European Heart Journal 2024, 45: ehae666.2256. DOI: 10.1093/eurheartj/ehae666.2256.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmRandomized controlled trialsPooled risk ratioB-blockersAortic aneurysmAortic dissectionControlled trialsAortic eventsRisk ratioPrimary outcomePooled risk estimatesRisk of aortic dissectionRisk of bias assessmentNo treatmentMeta-analysis of randomized controlled trialsInverse variance-weighted random-effects modelMeta-analysisLiterature searchB-blocker treatmentSystematic review protocolInternational Prospective RegisterCochrane Central Register of Controlled TrialsEfficacy of beta blockersCentral Register of Controlled TrialsSummary effect measuresA GENERAL APPROACH TO SOLVING THE PROBLEM OF ENSURING THE EFFICIENCY OF TRACTORS IN THE AGRO-INDUSTRIAL INDUSTRY
Galiev I, Ziganshin B, Kalimullin M, Adigamov N, Gabdrafikov F. A GENERAL APPROACH TO SOLVING THE PROBLEM OF ENSURING THE EFFICIENCY OF TRACTORS IN THE AGRO-INDUSTRIAL INDUSTRY. Vestnik Of Kazan State Agrarin University 2024, 19: 44-50. DOI: 10.12737/2073-0462-2024-44-50.Peer-Reviewed Original ResearchConceptsAmount of wearConsumption of aggregatesOperation of equipmentOperating conditions of machineryCondition of machineryOperating conditionsTractor unitWearTractor parametersNominal valuePlanning periodTractor systemEquipment systemResource consumptionOperation of tractorsTechnical conditionPhysical parametersTractorMechanical workOperationGenetics of aortic aneurysm disease: 10 key points for the practitioner
Elefteriades J, Zafar M, Ziganshin B. Genetics of aortic aneurysm disease: 10 key points for the practitioner. JTCVS Open 2024, 21: 58-63. PMID: 39534337, PMCID: PMC11551243, DOI: 10.1016/j.xjon.2024.07.014.Peer-Reviewed Original ResearchSomatic Variants Acquired Later in Life Associated with Thoracic Aortic Aneurysms: JAK2 V617F
Waldron C, Zafar M, Ma D, Zhang H, Dykas D, Ziganshin B, Popa A, Jha A, Kwan J, Elefteriades J. Somatic Variants Acquired Later in Life Associated with Thoracic Aortic Aneurysms: JAK2 V617F. Genes 2024, 15: 883. PMID: 39062663, PMCID: PMC11276600, DOI: 10.3390/genes15070883.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmDevelopment of thoracic aortic aneurysmAortic aneurysmJAK2 V617FMyeloproliferative neoplasmsSomatic variantsPrevalence of thoracic aortic aneurysmsDescending thoracic aortic aneurysmJAK2 V617F burdenAortic valve diseaseTarget of therapyDriver of myeloproliferative neoplasmsSurgical aortic replacementVariant allele fractionAscending thoracic aortic aneurysmAortic replacementAneurysm sizeAneurysm patientsValve diseaseVariant carriersIncreased riskJAK2 geneExome sequencing databaseAllele fractionAneurysmPatient-specific ascending aortic intervention criteria
Kalogerakos P, Zafar M, Li Y, Ellauzi H, Mukherjee S, Ziganshin B, Rizzo J, Elefteriades J. Patient-specific ascending aortic intervention criteria. European Journal Of Cardio-Thoracic Surgery 2024, 65: ezae162. PMID: 38632077, DOI: 10.1093/ejcts/ezae162.Peer-Reviewed Original ResearchCitationsConceptsAdverse aortic eventsRisk of adverse eventsAortic eventsAortic rootAneurysm patientsAscending aortaAdverse eventsIncreased risk of adverse eventsThoracic aortic aneurysm patientsAscending aortic aneurysmHigher risk of adverse eventsAortic aneurysm patientsAscending thoracic aortic aneurysm patientsBody surface areaGeneral populationPersonalized risk stratificationAortic diameterAneurysm locationRisk stratificationAortic aneurysmIncreased riskAscending diameterPatientsHigh riskZ-score
2023
DETERMINING THE ENERGY CONSUMPTION OF THE PROCESS OF GRINDING BY CUTTING IN A FEED GRINDER
Popoldnev R, Ziganshin B, Aleshkin A, Dmitriev A, Haliullin D, Gayfullin I. DETERMINING THE ENERGY CONSUMPTION OF THE PROCESS OF GRINDING BY CUTTING IN A FEED GRINDER. Vestnik Of Kazan State Agrarin University 2023, 18: 82-88. DOI: 10.12737/2073-0462-2023-82-88.Peer-Reviewed Original ResearchConceptsGrinding processCutting workTheory of elasticityTheory of shellsAngle of inclinationCutting zoneRotor speedFracture mechanicsRotor driveEnergy consumptionWorking chamberTechnological parametersRotorGrindingGeometric characteristicsUnloaded chamberChopperMathematical modelOriginal shapeZootechnical requirementsTruncated coneAnalytical expressionsNutritive value of feedsFeeds of plant originUniform supplyMidterm follow-up of composite graft replacement of the aortic root (30-year experience)—remarkably safe, effective, and durable
Jeoffrey S, Zafar M, Velasco J, Khattak A, Ellauzi H, Nasir A, Kalyanasundaram A, Ziganshin B, Elefteriades J. Midterm follow-up of composite graft replacement of the aortic root (30-year experience)—remarkably safe, effective, and durable. JTCVS Open 2023, 17: 1-13. PMID: 38420531, PMCID: PMC10897671, DOI: 10.1016/j.xjon.2023.11.007.Peer-Reviewed Original ResearchAltmetricConceptsAortic root replacementOperative mortalityTerm outcomesDistal aortic segmentsLong-term bleedingAortic root diseaseComposite graft replacementType A DissectionFirst-time operationsAge/genderARR patientsConcomitant CABGLate reoperationAcute typeRoot replacementAdverse eventsGraft failureGraft replacementRedo proceduresCabrol procedureUrgent operationAortic rootAortic segmentsPatientsOperative choiceEvidence Accumulates: Patients with Ascending Aneurysms Are Strongly Protected from Atherosclerotic Disease
Waldron C, Zafar M, Ziganshin B, Weininger G, Grewal N, Elefteriades J. Evidence Accumulates: Patients with Ascending Aneurysms Are Strongly Protected from Atherosclerotic Disease. International Journal Of Molecular Sciences 2023, 24: 15640. PMID: 37958625, PMCID: PMC10650782, DOI: 10.3390/ijms242115640.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsThoracic aortic aneurysmAortic aneurysmCarotid intima-media thicknessLow-density lipoprotein levelsIntima-media thicknessDevelopment of atherosclerosisMatrix metalloproteinase proteinsAscending aneurysmAortic calcificationAtherosclerotic diseaseLipoprotein levelsMyocardial infarctionLeading causeAneurysmsMetalloproteinase proteinsGrowth factorProtective relationshipDiseasePossible mechanismCurrent understandingMorbidityInfarctionAtherosclerosisPatientsPathophysiology
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