1999
Leptin and the Perioperative Neuroendocrinological Stress Response1
Kain Z, Zimolo Z, Heninger G. Leptin and the Perioperative Neuroendocrinological Stress Response1. The Journal Of Clinical Endocrinology & Metabolism 1999, 84: 2438-2442. PMID: 10404818, DOI: 10.1210/jcem.84.7.5850.Peer-Reviewed Original ResearchConceptsSurgical stressLeptin decreaseHigh-dose opioid techniqueCortisol increasePhase IHigh-dose fentanylSurgical stress responseTotal abdominal hysterectomyCardiac surgery patientsBaseline 2 hPossible adverse outcomesBaseline 24 hPhase IIAcute stress responseDose fentanylAbdominal hysterectomyPostoperative morbiditySurgery patientsHysterectomy patientsLeptin levelsAnesthetic techniqueAdverse outcomesAdrenocortical axisCardiac patientsNeuroendocrine hormones
1998
The Sedative and Analgesic Sparing Effect of Music
Koch M, Kain Z, Ayoub C, Rosenbaum S. The Sedative and Analgesic Sparing Effect of Music. Anesthesiology 1998, 89: 300-306. PMID: 9710387, DOI: 10.1097/00000542-199808000-00005.Peer-Reviewed Original ResearchConceptsDuration of surgeryAnalgesic requirementsIntraoperative musicPatient-controlled intravenous opioid analgesiaAnalgesic sparing effectIntravenous opioid analgesiaIntravenous propofol sedationPostanesthesia care unitEffects of musicMusic groupDuration of stayPhase 2Phase 1Operating room noiseAlfentanil requirementsOpioid analgesiaAdverse eventsLess propofolSpinal anesthesiaAwake patientsCare unitAdverse outcomesPropofol sedationSparing effectUreteral calculi