Glucosamine mitigates ischemia-reperfusion-induced acute kidney injury through anti-inflammatory mechanisms
Zhang G, Jin S, Fan X, Qi J, Liu J, Yin S, Cao Y, Du Y, Dong X, Wang Z, Tan X, Yan S. Glucosamine mitigates ischemia-reperfusion-induced acute kidney injury through anti-inflammatory mechanisms. Frontiers In Materials 2024, 11: 1438610. DOI: 10.3389/fmats.2024.1438610.Peer-Reviewed Original ResearchAcute kidney injuryTubular epithelial cellsKidney injuryI/R injuryRenal tissueEpithelial cellsInflammatory responseRenal ischemia-reperfusion (I/R) injuryIschemia-reperfusion-induced acute kidney injuryI/R-induced acute kidney injuryEndoplasmic reticulumIschemia-reperfusion (I/R) injuryProximal tubular epithelial cellsMarkers of oxidative stressEfficacy of glucosaminePotential therapeutic efficacyProximal convoluted tubular epithelial cellsRenal interstitial fibrosisI/R injury modelAnti-inflammatory actionMitigate ER stressAnti-inflammatory mechanismsAssessed in vitroOxidative stress levelsReduced oxidative stress levels