Preparation of Paeonol Ethosomes by Microfluidic Technology Combined with Gaussians and Evaluation of Biological Activity by Zebrafish
Tian M, Zhang Z, Wang L, Lei F, Wang Z, Ma X, Gong Z, Wang J, He J, Wang D. Preparation of Paeonol Ethosomes by Microfluidic Technology Combined with Gaussians and Evaluation of Biological Activity by Zebrafish. ACS Omega 2024, 9: 44425-44435. PMID: 39524614, PMCID: PMC11541796, DOI: 10.1021/acsomega.4c05830.Peer-Reviewed Original ResearchPoor water solubilityLow bioavailabilityProbability of spreadZeta potentialPolydispersity indexFourier transform infrared spectroscopyTransmission electron microscopyTransform infrared spectroscopyVesicle sizeWater solubilitySlow-release effectInfrared spectroscopyFT-IREthosomesBioavailabilityConcentrationAnti-inflammatory effectsHydroethanolic solutionTransdermal absorptionElectron microscopySkin retentionDensity functional theory analysisEvaluation of biological activityZebrafish resultsZeta