2008
Specification of Motor Axon Trajectory by Ephrin-B:EphB Signaling: Symmetrical Control of Axonal Patterning in the Developing Limb
Luria V, Krawchuk D, Jessell T, Laufer E, Kania A. Specification of Motor Axon Trajectory by Ephrin-B:EphB Signaling: Symmetrical Control of Axonal Patterning in the Developing Limb. Neuron 2008, 60: 1039-1053. PMID: 19109910, DOI: 10.1016/j.neuron.2008.11.011.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAxonsBody PatterningChick EmbryoElectroporationEmbryo, MammalianEphrinsExtremitiesGene Expression Regulation, DevelopmentalGreen Fluorescent ProteinsHomeodomain ProteinsHorseradish PeroxidaseLIM-Homeodomain ProteinsMiceMice, KnockoutModels, BiologicalMotor NeuronsMutationNeurofilament ProteinsReceptors, Eph FamilyRNA, MessengerSignal TransductionSpinal CordTranscription Factors
2007
Lateral motor column axons execute a ternary trajectory choice between limb and body tissues
Luria V, Laufer E. Lateral motor column axons execute a ternary trajectory choice between limb and body tissues. Neural Development 2007, 2: 13. PMID: 17605791, PMCID: PMC1949814, DOI: 10.1186/1749-8104-2-13.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAxonsBody PatterningBone Morphogenetic Protein Receptors, Type ICell DifferentiationEphrinsExtremitiesGene Expression Regulation, DevelopmentalGrowth ConesHomeodomain ProteinsKruppel-Like Transcription FactorsLIM-Homeodomain ProteinsMesodermMiceMice, KnockoutMotor NeuronsMuscle, SkeletalNeuronal PlasticityPromyelocytic Leukemia Zinc Finger ProteinReceptors, Eph FamilySpinal CordTranscription FactorsConceptsLateral motor columnLMC axonsHindlimb levelsSpinal cord lateral motor columnMotor columnAxons of neuronsIntermediate choice pointsVentral flankBody tissuesMotor nervesLMC neuronsAxonal trajectoriesLimb trajectoriesAxonsTopographic map formationTarget tissuesLimbTissueTranscription factor codeVentral limbNeuronsMap formationMesenchymeInnervationNerve
1998
Targeted Disruption of the Mouse Caspase 8 Gene Ablates Cell Death Induction by the TNF Receptors, Fas/Apo1, and DR3 and Is Lethal Prenatally
Varfolomeev E, Schuchmann M, Luria V, Chiannilkulchai N, Beckmann J, Mett I, Rebrikov D, Brodianski V, Kemper O, Kollet O, Lapidot T, Soffer D, Sobe T, Avraham K, Goncharov T, Holtmann H, Lonai P, Wallach D. Targeted Disruption of the Mouse Caspase 8 Gene Ablates Cell Death Induction by the TNF Receptors, Fas/Apo1, and DR3 and Is Lethal Prenatally. Immunity 1998, 9: 267-276. PMID: 9729047, DOI: 10.1016/s1074-7613(00)80609-3.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCaspase 8Caspase 9CaspasesCell DeathCells, CulturedCysteine EndopeptidasesDNA, ComplementaryFas ReceptorFetal DeathFibroblastsGene TargetingGenes, LethalGestational AgeMiceMice, Inbred C57BLMice, KnockoutPhenotypeReceptors, Tumor Necrosis FactorReceptors, Tumor Necrosis Factor, Member 25Transcription, GeneticConceptsFas/APO1Death inductionJun N-terminal kinaseHeart muscle developmentCaspase-8 geneCell death inductionWild-type fibroblastsN-terminal kinaseTNF receptorNull embryosMuscle developmentAlpha phosphorylationHematopoietic colony-forming cellsCaspase-8Cell deathColony-forming cellsIkappaB-alpha phosphorylationTargeted disruptionNonredundant roleEmbryonal developmentEmbryosAPO1Fibroblast strainsNGF familyReceptors