2020
Stress as tool or toxin: physiologic markers and subjective report in neonatal simulation
Redmond B, Joseph M, Ray J, Shabanova V, Gross IT, Bruno C, McPadden J, Auerbach M, Johnston L. Stress as tool or toxin: physiologic markers and subjective report in neonatal simulation. Pediatric Research 2020, 88: 784-791. PMID: 32045934, DOI: 10.1038/s41390-020-0806-9.Peer-Reviewed Original Research
2018
Reducing Radiation Exposure in Cardiac Catheterizations for Congenital Heart Disease
Patel C, Grossman M, Shabanova V, Asnes J. Reducing Radiation Exposure in Cardiac Catheterizations for Congenital Heart Disease. Pediatric Cardiology 2018, 40: 638-649. PMID: 30542920, DOI: 10.1007/s00246-018-2039-9.Peer-Reviewed Original ResearchConceptsCatheterization labRadiation exposureCardiac catheterizationYale-New Haven Children's HospitalDAP/Patent ductus arteriosusAtrial septal defectCongenital heart diseaseDose area productSystems-based interventionsCardiac catheterization labCongenital cardiac catheterizationTotal air kermaPost-intervention dataRadiation dose reductionAir kermaQuality improvement strategiesDuctus arteriosusTranscatheter pulmonaryChildren's HospitalDA dosesSeptal defectHeart diseaseLow fluoroscopyProcedure type
2017
Ventricular arrhythmias immediately following transcatheter pulmonary valve implantation: A cause for concern?
Simmons MA, Elder RW, Shabanova V, Hellenbrand W, Asnes J. Ventricular arrhythmias immediately following transcatheter pulmonary valve implantation: A cause for concern? Catheterization And Cardiovascular Interventions 2017, 91: 920-926. PMID: 29280541, DOI: 10.1002/ccd.27454.Peer-Reviewed Original ResearchConceptsTranscatheter pulmonary valve implantationRight ventricular outflow tractNative outflow tractsSignificant ventricular arrhythmiasPulmonary valve implantationVentricular arrhythmiasOutflow tractValve implantationAnti-arrhythmic medicationsBeta-blocker therapySingle-center studyVentricular outflow tractLong-term therapySudden cardiac deathCare of patientsChange of doseHemodynamic instabilityHemodynamic compromiseCardiac deathMedian ageMedical therapyPediatric patientsSignificant arrhythmiasCenter studyTerm therapyComparison of valvar and right ventricular function following transcatheter and surgical pulmonary valve replacement
Li WF, Pollard H, Karimi M, Asnes JD, Hellenbrand WE, Shabanova V, Weismann CG. Comparison of valvar and right ventricular function following transcatheter and surgical pulmonary valve replacement. Congenital Heart Disease 2017, 13: 140-146. PMID: 29148206, PMCID: PMC5796854, DOI: 10.1111/chd.12544.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBioprosthesisCardiac CatheterizationChildChild, PreschoolEchocardiographyFemaleFollow-Up StudiesHeart Valve Prosthesis ImplantationHeart VentriclesHumansMaleMiddle AgedPulmonary ValvePulmonary Valve InsufficiencyRetrospective StudiesTime FactorsTreatment OutcomeVentricular Function, RightVentricular RemodelingYoung AdultConceptsRight ventricular outflow tract obstructionPulmonary valve replacementSurgical pulmonary valve replacementRight ventricular functionPulmonic insufficiencyVentricular functionTC groupRV functionSurgical groupValve replacementRV sizeVentricular outflow tract obstructionYale-New Haven HospitalOutflow tract obstructionTract obstructionPatient ageRetrospective reviewSurgical valvesPostoperative declinePulmonary valveHigh riskValve functionPatientsFirst choiceTime pointsRisk factors for tracheostomy requirement in extremely low birth weight infants
Levit OL, Shabanova V, Bazzy-Asaad A, Bizzarro MJ, Bhandari V. Risk factors for tracheostomy requirement in extremely low birth weight infants. The Journal Of Maternal-Fetal & Neonatal Medicine 2017, 31: 447-452. PMID: 28139937, DOI: 10.1080/14767058.2017.1287895.Peer-Reviewed Original ResearchMeSH KeywordsAirway ExtubationCase-Control StudiesFemaleGestational AgeHumansInfantInfant, Extremely Low Birth WeightInfant, Extremely PrematureInfant, NewbornIntubation, IntratrachealMalePregnancyRespiration, ArtificialRetrospective StudiesRisk FactorsSeverity of Illness IndexTime FactorsTracheostomyConceptsLow birth weight infantsOdds of tracheostomyBirth weight infantsELBW infantsWeight infantsEndotracheal tubeRisk of tracheostomyPresence of comorbiditiesUse of steroidsCase-control studyConditional logistic regressionNumber of intubationsGreater cumulative exposureIntubation episodesTracheostomy requirementExtubation attemptGestational ageEpisodes/Risk factorsTracheostomyPrevious episodesCumulative exposurePoisson regressionCumulative daysInfants
2015
The relationship between voice climate and patients’ experience of timely care in primary care clinics
Nembhard IM, Yuan CT, Shabanova V, Cleary PD. The relationship between voice climate and patients’ experience of timely care in primary care clinics. Health Care Management Review 2015, 40: 104-115. PMID: 24589927, PMCID: PMC5428896, DOI: 10.1097/hmr.0000000000000017.Peer-Reviewed Original ResearchConceptsTimeliness of carePrimary care clinicsTimely carePatient care experiencesCare clinicsPatient experienceCare experiencesCross-sectional studyLess patientsStaff work environmentPatient reportsPatientsQuality careClinicAppointment timeCareClinical leadersAdministrative staffReportProfessional groupsWork environmentStaffAnalysis of varianceLeaders' reportsVoice climate
2014
The Temporal Kinetics of Circulating Angiopoietin Levels in Children With Sepsis
Giuliano JS, Tran K, Li FY, Shabanova V, Tala JA, Bhandari V. The Temporal Kinetics of Circulating Angiopoietin Levels in Children With Sepsis. Pediatric Critical Care Medicine 2014, 15: e1-e8. PMID: 24141659, PMCID: PMC3947338, DOI: 10.1097/pcc.0b013e3182a553bb.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAngiopoietin-1Angiopoietin-2BiomarkersCase-Control StudiesChildChild, PreschoolFemaleHumansIntensive Care Units, PediatricLength of StayMalePredictive Value of TestsProspective StudiesSepsisSeverity of Illness IndexShock, SepticSystemic Inflammatory Response SyndromeTime FactorsConceptsSevere sepsis/shockSepsis/shockSystemic inflammatory response syndrome/sepsisPediatric patientsShock groupAngiopoietin-2Day 2Angiopoietin-1Days of illnessHours of admissionIll pediatric patientsInflammatory response syndromeRisk stratification scoresProspective observational studyCritical care physiciansVascular growth factorsEnzyme-linked immunosorbentAngiopoietin levelsPICU lengthPICU patientsSevere sepsisSepsis severityResponse syndromeStratification scoresCare physicians
2013
Neutrophil CD64 with Hematologic Criteria for Diagnosis of Neonatal Sepsis
Streimish I, Bizzarro M, Northrup V, Wang C, Renna S, Koval N, Li FY, Ehrenkranz RA, Rinder HM, Bhandari V. Neutrophil CD64 with Hematologic Criteria for Diagnosis of Neonatal Sepsis. American Journal Of Perinatology 2013, 31: 021-030. PMID: 23456906, DOI: 10.1055/s-0033-1334453.Peer-Reviewed Original ResearchConceptsCulture-proven sepsisClinical sepsisNeutrophil CD64CD64 indexNeonatal sepsisHematologic criteriaSingle-centre neonatal intensive care unitEarly-onset clinical sepsisNeonatal intensive care unitNeutrophil CD64 indexProspective observational cohortAbsolute neutrophil countNormal birth weightIntensive care unitAbsolute band countNegative predictive valueAdditional markersSepsis evaluationNeutrophil countObservational cohortCare unitBirth weightHematologic parametersSepsisCD64
2011
“Change, before you have to.”–Jack Welch, Former CEO, General Electric*
Faustino EV, Lawson KA, Northrup V, Higgerson RA. “Change, before you have to.”–Jack Welch, Former CEO, General Electric*. Critical Care Medicine 2011, 40: 2227-2228. PMID: 21336130, PMCID: PMC3101274, DOI: 10.1097/ccm.0b013e31820eb8a1.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge FactorsCase-Control StudiesCatheterization, Central VenousCause of DeathChildChild, PreschoolCritical CareCritical IllnessFemaleHospital MortalityHumansInfantIntensive Care Units, PediatricMalePrognosisReference ValuesRespiration, ArtificialRetrospective StudiesRisk AssessmentSex FactorsSurvival AnalysisTime FactorsTreatment OutcomeVenous ThrombosisConceptsVentilator-free daysIntensive care unitCentral venous lineDeep venous thrombosisDeep vein thrombosisIndex patientsVenous thrombosisCare unitMechanical ventilationIll childrenControl patientsVein thrombosisVenous lineIntensive care unit-free daysIntensive care unit stayPrevious prospective observational studyPediatric intensive care unitCentral venous line insertionSymptomatic venous thromboembolismVenous thrombosis studyProspective observational studyAlternative outcome measuresUnit stayVenous thromboembolismCohort studyAntibiotic Exposure in the Newborn Intensive Care Unit and the Risk of Necrotizing Enterocolitis
Alexander VN, Northrup V, Bizzarro MJ. Antibiotic Exposure in the Newborn Intensive Care Unit and the Risk of Necrotizing Enterocolitis. The Journal Of Pediatrics 2011, 159: 392-397. PMID: 21489560, PMCID: PMC3137655, DOI: 10.1016/j.jpeds.2011.02.035.Peer-Reviewed Original ResearchConceptsRisk of NECAntibiotic exposureControl subjectsRisk factorsNewborn intensive care unitCulture-proven sepsisFull enteral feedingCases of NECIndependent risk factorDiagnosis of NECRespiratory distress syndromeIntensive care unitRisk factor dataPrior sepsisEnteral feedingNecrotizing enterocolitisDistress syndromeCare unitGestational ageBirth weightAntibiotic useCase subjectsSepsisMultivariate analysisNeonates
2010
Type and Timing of Ventilation in the First Postnatal Week is Associated with Bronchopulmonary Dysplasia/Death
Dumpa V, Northrup V, Bhandari V. Type and Timing of Ventilation in the First Postnatal Week is Associated with Bronchopulmonary Dysplasia/Death. American Journal Of Perinatology 2010, 28: 321-330. PMID: 21082539, DOI: 10.1055/s-0030-1268708.Peer-Reviewed Original ResearchConceptsNasal intermittent positive pressure ventilationNasal continuous positive airway pressureBPD/deathFirst postnatal weekGestational ageEndotracheal tubeBronchopulmonary dysplasiaPostnatal weekBronchopulmonary dysplasia/deathContinuous positive airway pressureIntermittent positive pressure ventilationFirst weekHealth consensus definitionRespiratory support modesMean gestational agePositive airway pressurePositive pressure ventilationWeeks gestational ageData of infantsAirway pressureRespiratory supportPremature infantsPressure ventilationConsensus definitionBody weight
2009
Comparison of Neurocognitive Functioning in Children Previously Randomly Assigned to Intrathecal Methotrexate Compared With Triple Intrathecal Therapy for the Treatment of Childhood Acute Lymphoblastic Leukemia
Kadan-Lottick NS, Brouwers P, Breiger D, Kaleita T, Dziura J, Northrup V, Chen L, Nicoletti M, Bostrom B, Stork L, Neglia JP. Comparison of Neurocognitive Functioning in Children Previously Randomly Assigned to Intrathecal Methotrexate Compared With Triple Intrathecal Therapy for the Treatment of Childhood Acute Lymphoblastic Leukemia. Journal Of Clinical Oncology 2009, 27: 5986-5992. PMID: 19884541, PMCID: PMC2793042, DOI: 10.1200/jco.2009.23.5408.Peer-Reviewed Original ResearchMeSH KeywordsAntimetabolites, AntineoplasticAntineoplastic Combined Chemotherapy ProtocolsAttentionChildChild, PreschoolCognitionCross-Sectional StudiesCytarabineFemaleHumansHydrocortisoneInfantInjections, SpinalIntelligence TestsLinear ModelsMaleMemoryMethotrexateNeuropsychological TestsPrecursor Cell Lymphoblastic Leukemia-LymphomaPsychomotor PerformanceTime FactorsTreatment OutcomeUnited StatesConceptsAcute lymphoblastic leukemiaIT therapyIntrathecal methotrexateMethotrexate groupLymphoblastic leukemiaChildhood acute lymphoblastic leukemiaTriple intrathecal therapyPost-therapy periodLong-term neurotoxicityNeurocognitive functioningAssociation of treatmentMajority of childrenCNS prophylaxisFull-scale intelligence quotientIntrathecal therapyNeurologic eventsPsychotropic medicationsVisual-motor integrationTherapy groupAttention/concentrationNeurocognitive evaluationIndex scoreTherapyPatientsMethotrexate