2012
Regulation of glomerulotubular balance. I. Impact of dopamine on flow-dependent transport
Du Z, Yan Q, Wan L, Weinbaum S, Weinstein A, Wang T. Regulation of glomerulotubular balance. I. Impact of dopamine on flow-dependent transport. American Journal Of Physiology. Renal Physiology 2012, 303: f386-f395. PMID: 22552936, PMCID: PMC3433864, DOI: 10.1152/ajprenal.00531.2011.Peer-Reviewed Original ResearchMeSH Keywords8-Bromo Cyclic Adenosine MonophosphateAlgorithmsAnimalsBenzazepinesBicarbonatesBiological Transport, ActiveChloridesCyclic AMP-Dependent Protein KinasesDopamineDopamine AntagonistsDopamine D2 Receptor AntagonistsFemaleIsoquinolinesKidney GlomerulusKidney TubulesKidney Tubules, ProximalMacrolidesMiceMicrovilliProton-Translocating ATPasesReceptors, Dopamine D1SodiumSulfonamidesSulpirideConceptsNa/H exchanger 3Impact of dopamineNa(+) transportNa-K-ATPase activityResponse to volume expansionProximal tubules in vitroCl(-) reabsorptionPKA-mediated mechanismMicroperfused in vitroEffects of exogenous dopamineMouse proximal tubuleNa-K-ATPaseProximal tubule reabsorptionStimulation of Cl(-PKA inhibitor H89Luminal flowH-ATPase activityTubules in vitroLuminal flow rateNHE3 activityDA1 receptorsNa/H exchangeTubule reabsorptionProximal tubulesInhibitor H89
2011
DOPAMINE MODULATES FLOW‐DEPENDENT TRANSPORT BY NHE3, BUT NOT H+‐ATPASE, IN MOUSE PROXIMAL TUBULES
Du Z, Gotoh N, Weinbaum S, Weinstein A, Wang T. DOPAMINE MODULATES FLOW‐DEPENDENT TRANSPORT BY NHE3, BUT NOT H+‐ATPASE, IN MOUSE PROXIMAL TUBULES. The FASEB Journal 2011, 25: 1041.18-1041.18. DOI: 10.1096/fasebj.25.1_supplement.1041.18.Peer-Reviewed Original ResearchEffects of DAProtein kinase A inhibitor H89Proximal tubules in vitroPKA-mediated mechanismProximal tubule transportReabsorption of fluidTubules in vitroHCO3- absorptionLuminal perfusion rateTubule transportJHCO3Cl- transportProximal tubulesNHE3Perfusion rateDopamineSCH23390JNaPresence of DAInhibitory effectSignaling mechanismsH+-ATPaseDA1No effectFlow-dependent transport
2010
ROLE OF DOPAMINE IN MODULATING FLOW‐DEPENDENT SODIUM AND BICARBONATE TRANSPORT IN MOUSE PROXIMAL TUBULE
Du Z, Yan Q, Weinbaum S, Weinstein A, Wang T. ROLE OF DOPAMINE IN MODULATING FLOW‐DEPENDENT SODIUM AND BICARBONATE TRANSPORT IN MOUSE PROXIMAL TUBULE. The FASEB Journal 2010, 24: 1024.2-1024.2. DOI: 10.1096/fasebj.24.1_supplement.1024.2.Peer-Reviewed Original ResearchProximal tubule transportEffects of dopamineMouse proximal tubuleTubule transportProximal tubulesNHE3 endocytosisCAMP-dependent protein kinase inhibitor H89PKA-mediated mechanismMicroperfused in vitroProtein kinase inhibitor H89Kidney proximal tubulesReabsorption of fluidLuminal flow rateKinase inhibitor H89Sodium reabsorptionApical membraneHCO-3 absorptionInhibitor H89DopaminePerfusion rateTubulesSCH23390NHE3Net reabsorptionSulpiride