2024
Persistent bloodstream infection in children: examining the role for repeat blood cultures
Puthawala C, Feinn R, Rivera-Viñas J, Lee H, Murray T, Peaper D. Persistent bloodstream infection in children: examining the role for repeat blood cultures. Journal Of Clinical Microbiology 2024, 62: e00998-24. PMID: 39365070, PMCID: PMC11559050, DOI: 10.1128/jcm.00998-24.Peer-Reviewed Original ResearchPositive blood culturesPersistent bloodstream infectionBlood culturesBloodstream infectionsCentral venous catheterPositive culturesVenous cathetersIndex blood cultureCross-sectional study of childrenRepeated blood culturesTime of blood drawElevated inflammatory markersAssociated with persistenceGt;48 hoursIndex cultureCross-sectional studyPersistent bacteremiaImmune dysfunctionPediatric patientsInflammatory markersDiagnostic stewardshipStudy of childrenPatient characteristicsClinical valueBlood draw
2019
Shifting focus toward healthcare-associated bloodstream infections: The need for neonatal intensive care unit–specific NHSN definitions
Advani SD, Murray TS, Murdzek CM, Aniskiewicz MJ, Bizzarro MJ. Shifting focus toward healthcare-associated bloodstream infections: The need for neonatal intensive care unit–specific NHSN definitions. Infection Control And Hospital Epidemiology 2019, 41: 181-186. PMID: 31694731, DOI: 10.1017/ice.2019.310.Peer-Reviewed Original ResearchConceptsBloodstream infectionsNHSN definitionsNICU populationSite-specific definitionClinical definitionNational Healthcare Safety Network definitionsNeonatal intensive care unit populationIntensive care unit populationHealthcare-associated bloodstream infectionsYale-New Haven Children's HospitalLevel IV NICUSafety Network definitionsDirect prevention effortsMcNemar χ2 testSource of infectionGut translocationPreterm neonatesRespiratory supportPremature infantsRetrospective reviewChildren's HospitalPatient daysIncidence rateNICU teamUnit population585. Shifting Focus Toward Healthcare-Associated Bloodstream Infections: Need for More NICU-Specific NHSN Definitions
Advani S, Murray T, Bizzarro M. 585. Shifting Focus Toward Healthcare-Associated Bloodstream Infections: Need for More NICU-Specific NHSN Definitions. Open Forum Infectious Diseases 2019, 6: s276-s277. PMCID: PMC6810847, DOI: 10.1093/ofid/ofz360.654.Peer-Reviewed Original ResearchCentral line-associated bloodstream infectionsBloodstream infectionsNHSN definitionsChi-square testClinical definitionNational Healthcare Safety Network definitionsNeonatal intensive care unit populationIntensive care unit populationYale-New Haven Children's HospitalLine-associated bloodstream infectionsLevel IV NICUSafety Network definitionsMedian birth weightPercent of patientsSepsis-related mortalityHours of lifeHealthcare-Associated Bloodstream InfectionsMcNemar chi-square testPositive blood culturesSource of infectionGut translocationParenteral nutritionNICU populationRetrospective reviewGestational age